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GlossaryTopical Finasteride

medication applied to the scalp to treat hair loss

Topical Finasteride is a medication applied directly to the scalp to treat hair loss, particularly androgenetic alopecia (male or female pattern baldness). Unlike oral finasteride, which can have systemic side effects, the topical form aims to reduce these risks by delivering the drug directly to the affected area, thereby minimizing its absorption into the bloodstream.

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Research

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Patient-Reported Outcomes of Topical Finasteride/Minoxidil Treatment for Male Androgenetic Alopecia: A Retrospective Study Using Telemedical Data

research Patient‐reported outcomes of topical finasteride/minoxidil treatment for male androgenetic alopecia: A retrospective study using telemedical data

May 2024 in “Journal of cosmetic dermatology”

Topical finasteride/minoxidil is effective but not better than oral finasteride for hair loss.

Efficacy of Topical Minoxidil and Finasteride Combination Versus Monotherapy in Men With Androgenetic Alopecia: A Prospective, Randomized, Controlled, Assessor-Blinded, 3-Arm, Pilot Trial

research Faculty Opinions recommendation of Efficacy of the association of topical minoxidil and topical finasteride compared to their use in monotherapy in men with androgenetic alopecia: A prospective, randomized, controlled, assessor blinded, 3-arm, pilot trial.

October 2023 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature”

Using both minoxidil and finasteride together on the scalp works better for male hair loss than using either one alone.

Comparative Efficacy of Topical Finasteride (0.25%) in Combination With Minoxidil (5%) Against 5% Minoxidil or 0.25% Finasteride Alone in Male Androgenetic Alopecia: A Pilot, Randomized Open-Label Study

research Comparative efficacy of topical finasteride (0.25%) in combination with minoxidil (5%) against 5% minoxidil or 0.25% finasteride alone in male androgenetic alopecia: A pilot, randomized open-label study

March 2023 in “International Journal of Trichology”

Using both minoxidil and finasteride together is more effective for male hair loss than using either one alone.

The Efficacy and Safety of Finasteride Combined with Topical Minoxidil for Androgenetic Alopecia: A Systematic Review and Meta-Analysis

research The Efficacy and Safety of Finasteride Combined with Topical Minoxidil for Androgenetic Alopecia: A Systematic Review and Meta-analysis

8 citations , March 2020 in “Aesthetic Plastic Surgery”

Finasteride and minoxidil together safely and effectively increase hair growth and density for androgenetic alopecia.

Hair Growth Effects of Oral Administration of Finasteride, a Steroid 5 Alpha-Reductase Inhibitor, Alone and in Combination with Topical Minoxidil in the Balding Stumptail Macaque

research Hair growth effects of oral administration of finasteride, a steroid 5 alpha-reductase inhibitor, alone and in combination with topical minoxidil in the balding stumptail macaque.

34 citations , February 1992 in “The Journal of Clinical Endocrinology and Metabolism”

Finasteride and minoxidil together promote hair growth better than either alone.

Topical Minoxidil Fortified with Finasteride: Maintenance of Hair Density After Replacing Oral Finasteride

research Topical minoxidil fortified with finasteride: An account of maintenance of hair density after replacing oral finasteride

32 citations , January 2015 in “Indian Dermatology Online Journal”

Minoxidil and finasteride combo maintains hair density effectively.

research Comparing the therapeutic efficacy of topical minoxidil and finasteride with topical minoxidil and oral finasteride in androgenetic alopecia: a randomized trial

4 citations , July 2018 in “International Journal of Research in Dermatology”

Topical finasteride with minoxidil is effective for treating hair loss and may reduce the need for oral finasteride.

A Cross-Sectional Randomized Comparative Study of Topical Minoxidil Solution With and Without Finasteride in Male Pattern Androgenetic Alopecia in South Indian Patients

research A cross-sectional randomized comparative study of topical minoxidil solution with and without finasteride in male pattern androgenetic alopecia in South Indian patients

1 citations , January 2018 in “International Journal of Research in Dermatology”

Adding finasteride to minoxidil solution for hair loss treatment didn't show extra benefits, just increased cost and fear of side effects.

Efficacy of Topical Minoxidil and Finasteride Association Compared to Monotherapy in Men With Androgenetic Alopecia: A Prospective, Randomized, Controlled, Assessor-Blinded, 3-Arm, Pilot Trial

research Efficacy of the association of topical minoxidil and topical finasteride compared to their use in monotherapy in men with androgenetic alopecia: A prospective, randomized, controlled, assessor blinded, 3‐arm, pilot trial

October 2023 in “Journal of Cosmetic Dermatology”

Using both minoxidil and finasteride together is more effective for hair growth than using either one alone in men with hair loss.

Efficacy of Topical Minoxidil and Oral Spironolactone Versus Minoxidil and Finasteride in Androgenic Alopecia

research The efficacy of the combination of topical minoxidil and oral spironolactone compared with the combination of topical minoxidil and oral finasteride in women with androgenic alopecia, female and male hair loss patterns: A blinded randomized clinical trial

August 2023 in “Journal of Cosmetic Dermatology”

Both minoxidil-spironolactone and minoxidil-finasteride treatments work for hair loss, but minoxidil-spironolactone is slightly more effective, especially in women.

research Topical minoxidil fortified with finasteride: An account of maintenance of hair density after replacing oral finasteride

August 2016 in “International journal of scientific research”

Using minoxidil with finasteride in a cream helps maintain hair thickness after stopping oral finasteride.

Comparative Effects of Monotherapy with Topical Minoxidil, Oral Finasteride, and Topical Finasteride in Postmenopausal Women with Pattern Hair Loss: A Retrospective Cohort Study

research The Comparative Effects of Monotherapy with Topical Minoxidil, Oral Finasteride, and Topical Finasteride in Postmenopausal Women with Pattern Hair Loss: A Retrospective Cohort Study

January 2024 in “Skin appendage disorders”

Oral finasteride seems more effective for hair loss in postmenopausal women, but more research is needed.

research Efficacy and Tolerability of a Topical Gel Containing Mimicking Growth Factors Oligopeptides, Caffeine, Taurine and an Iron-Chelating Complex in Subjects with Androgenetic Alopecia Treated with Topical Minoxidil or Oral Finasteride: a Prospective, 6-Month, Randomized, Assessor-Blinded, 4-Arm, Parallel Group Study

December 2022 in “Clinical and experimental dermatology and therapies”

Adding the topical gel improved hair growth more than using minoxidil or finasteride alone.

research Comparative study of efficacy of topical minoxidil versus topical minoxidil with finasteride in androgenetic alopecia

April 2021 in “International Journal of Research in Dermatology”

The combination of minoxidil and finasteride is more effective for hair growth than minoxidil alone.

research Improvement in Androgenetic Alopecia (Stage V) Using Topical Minoxidil in a Retinoid Vehicle and Oral Finasteride

23 citations , December 1995 in “Archives of Dermatology”

Combination therapy improves hair growth in advanced hair loss.

research Oral Finasteride (5 mg and 2 mg) versus Topical Minoxidil 5% in Female Pattern Hair Loss

January 2025 in “Clinical Dermatology Review”

Finasteride 5 mg and topical minoxidil 5% effectively increase hair density in women, with finasteride 5 mg having the highest satisfaction.

Evaluation of Platelet-Rich Plasma Versus Topical Minoxidil (5%) in Combination with Oral Finasteride for the Treatment of Androgenic Alopecia

research Evaluation of Platelet-Rich Plasma (PRP) Versus Topical Minoxidil (5%) in Combination with Oral Finasteride for the Treatment of Androgenic Alopecia

August 2024 in “Pakistan Journal of Health Sciences”

PRP with finasteride is better for hair regrowth than minoxidil with finasteride.

research Efficacy and safety of 10% topical minoxidil, oral finasteride and microneedling in Male Pattern Baldness

June 2017 in “IP Indian journal of clinical and experimental dermatology”

Using 10% topical minoxidil, oral finasteride, and microneedling together can effectively treat Male Pattern Baldness with high patient satisfaction and no major side effects.

research Improvement in androgenetic alopecia (stage V) using topical minoxidil in a retinoid vehicle and oral finasteride

1 citations , December 1995 in “Archives of Dermatology”

The combination of topical minoxidil and oral finasteride improved hair regrowth in a man with advanced hair loss.

research 62471 Topical Finasteride Combined with Minoxidil for Androgenetic Alopecia: An Updated Systematic Review and Meta-analysis

September 2025 in “Journal of the American Academy of Dermatology”

Combining topical finasteride with minoxidil significantly improves hair density in treating hair loss.

Clinical and Trichoscopic Evaluations of Topical Finasteride 1%, Topical Spironolactone 5%, and Minoxidil 5% in Female Pattern Hair Loss Treatment

research Clinical and Trichoscopic Evaluations of Topical Finasteride 1%, Topical Spironolactone 5%, and Minoxidil 5% in Female Pattern Hair Loss Treatment

January 2025 in “Dermatology Practical & Conceptual”

Topical finasteride is as effective and safe as minoxidil for treating female pattern hair loss.

research A study to compare the efficacy and safety of platelet rich plasma and topical minoxidil fortified with finasteride in the treatment of androgenic alopecia in male patients

June 2022 in “IP Indian journal of clinical and experimental dermatology”

Both treatments were equally effective in promoting hair growth.

Efficacy of Topical Combination of 0.25% Finasteride and 3% Minoxidil Versus 3% Minoxidil Solution in Female Pattern Hair Loss: A Randomized, Double-Blind, Controlled Study

research Efficacy of Topical Combination of 0.25% Finasteride and 3% Minoxidil Versus 3% Minoxidil Solution in Female Pattern Hair Loss: A Randomized, Double-Blind, Controlled Study

36 citations , September 2018 in “American Journal of Clinical Dermatology”

Combination of 0.25% finasteride and 3% minoxidil works better than just 3% minoxidil for increasing hair thickness in women.

Efficacy of Topical Finasteride 0.25% With Minoxidil 5% Versus Topical Minoxidil 5% Alone in the Treatment of Male Pattern Androgenic Alopecia

research Efficacy of Topical Finasteride 0.25% With Minoxidil 5% Versus Topical Minoxidil 5% Alone in Treatment of Male Pattern Androgenic Alopecia

October 2024 in “Journal of Drugs in Dermatology”

Combining finasteride with minoxidil is more effective for male hair loss than using minoxidil alone.

research Development and Validation of HPLC Method for Simultaneous Estimation of Minoxidil and Finasteride in Topical Solution

December 2023 in “International Journal of Advanced Research in Science, Communication and Technology”

A reliable method was created to measure Minoxidil and Finasteride in a solution.

research Comparison of Microneedling with Platelet Rich Plasma vs Minoxidil (5%)+Finasteride (0.1%) Topical Therapy in Androgenetic Alopecia: A Randomised Clinical Study

January 2023 in “Journal of Clinical and Diagnostic Research”

Microneedling with PRP is as effective and safe as minoxidil+finasteride for treating hair loss.

Efficacy and Safety of Topical Combination of 3% Minoxidil and 0.25% Finasteride Versus 3% Minoxidil Solution in Female-Pattern Hair Loss: A Randomized, Double-Blind, Controlled Study

research Efficacy and safety of topical combination of 3% minoxidil and 0.25% finasteride versus 3% minoxidil solution in female-pattern hair loss: A randomized, double-blind, controlled study

1 citations , August 2018 in “Journal of The American Academy of Dermatology”

Combination of minoxidil and finasteride is more effective in increasing hair diameter than minoxidil alone for female-pattern hair loss.

research Clinical Efficacy of a Topical Compounded Formulation in Male Androgenetic Alopecia: Minoxidil 10%, Finasteride 0.1%, Biotin 0.2%, and Caffeine Citrate 0.05% Hydroalcoholic Solution.

1 citations , February 2020 in “PubMed”

The topical solution improved hair density and appearance in men with androgenetic alopecia.

Combined Treatment with Oral Finasteride and Topical Minoxidil in Male Androgenetic Alopecia: A Randomized and Comparative Study in Chinese Patients

research Combined treatment with oral finasteride and topical minoxidil in male androgenetic alopecia: a randomized and comparative study in Chinese patients

32 citations , June 2015 in “Dermatologic Therapy”

Finasteride and minoxidil together work best for male hair loss.

Comparative Study of Topical Minoxidil (5%) Plus Finasteride (0.1%) Versus Platelet-Rich Plasma Plus Topical Minoxidil (5%) Plus Finasteride (0.1%) in Patients with Androgenic Alopecia

research COMPARITIVE STUDY OF TOPICAL MINOXIDIL (5%) PLUS FINASTERIDE (0.1%) VERSUS PLATELET-RICH PLASMA PLUS TOPICAL MINOXIDIL (5%) PLUS FINASTERIDE (0.1%) IN PATIENTS WITH ANDROGENIC ALOPECIA

December 2024 in “Asian Journal of Pharmaceutical and Clinical Research”

Adding PRP to minoxidil and finasteride is more effective for hair loss.