research 5α‐Reductase Isozymes and Androgen Actions in the Prostate
5α‐reductase isozymes are crucial for prostate development and health, and targeting them can help prevent and treat prostate issues.
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research Polycystic Ovary Syndrome
PCOS is a common hormonal disorder in women, marked by symptoms like hair growth and menstrual issues, and requires personalized treatment.
research Clinical and biological impact of the exposome on the skin
Environmental factors, hormones, nutrition, and stress all significantly affect skin health and aging.
research Dermal Papilla Cells Improve the Wound Healing Process and Generate Hair Bud-Like Structures in Grafted Skin Substitutes Using Hair Follicle Stem Cells
Dermal papilla cells help wounds heal better and can potentially grow new hair.
research The C3H/HeJ mouse and DEBR rat models for alopecia areata: review of preclinical drug screening approaches and results
Both mouse and rat models are effective for testing alopecia areata treatments.
research ACNE
Acne significantly affects mental health and quality of life, with research suggesting hormonal and genetic factors in its development and emphasizing early treatment to prevent scarring.
research Modulation of glucocorticoid action and the treatment of type-2 diabetes
Targeting glucocorticoid action might help treat type-2 diabetes, but human trials are needed.
research The mineralocorticoid receptor as a novel player in skin biology: beyond the renal horizon?
The mineralocorticoid receptor may play a role in skin and hair health and could be a new target for treating related disorders.
research Stem Cell-Based Tissue Engineering for the Treatment of Burn Wounds: A Systematic Review of Preclinical Studies
Stem cell treatments may improve burn wound healing.
research Differential expression analysis of balding and nonbalding dermal papilla microRNAs in male pattern baldness with a microRNA amplification profiling method
Certain microRNAs are more common in balding areas and might be involved in male pattern baldness.
research Mesotherapy for local fat reduction
Mesotherapy might help reduce fat in specific areas for those close to their ideal weight, but more research and care are needed to ensure safety.
research Efficacy of combination therapy of inositols, antioxidants and vitamins in obese and non-obese women with polycystic ovary syndrome: an observational study
The combination therapy improved PCOS symptoms in both obese and non-obese women, with weight loss in the obese group.
research Icariin promotes mouse hair follicle growth by increasing insulin-like growth factor 1 expression in dermal papillary cells
Icariin helps mouse hair grow by boosting a growth factor in skin cells.
research Telogen Effluvium: Is There a Need for a New Classification
The paper suggests improving diagnosis and treatment of telogen effluvium but does not recommend a new classification system.
research Comprehension Testing for OTC Drug Labels: Goals, Methods, Target Population, and Testing Environment
The paper concludes that drug labels should be clear for all, especially for those with low literacy, and suggests aiming for high comprehension test passing rates with diverse test populations.
research Evidence for a functional interaction of WNT10A and EBF1 in male-pattern baldness
WNT10A and EBF1 interaction affects hair growth in male-pattern baldness.
research DPSCs and SHED in Tissue Engineering and Regenerative Medicine
DPSCs and SHED have great potential for medical treatments and tissue repair.
research A functional polymorphism in interleukin-1α (IL1A) gene is associated with risk of alopecia areata in Chinese populations
A certain genetic variation in the IL1A gene may lower the risk of a hair loss condition in Chinese people.
research Hormonal and reproductive factors and risk of upper gastrointestinal cancers in men: A prospective cohort study within the UK Biobank
Men with frontal male pattern baldness may have a higher risk of gastric cancer.
research Sustained release of inhibitor from bionic scaffolds for wound healing and functional regeneration
Researchers developed a scaffold that releases a healing drug over time, improving wound healing and skin regeneration.
research Functional ectodermal organ regeneration as the next generation of organ replacement therapy
The document concludes that regenerating functional ectodermal organs like teeth and hair is promising for future therapies.
research Effect of 150 kHz electromagnetic radiation on the development of polycystic ovaries induced by estradiol Valerate in Sprague Dawley rats
150 kHz electromagnetic radiation might help improve PCOS in rats.
research Sexual dimorphism following in vitro ischemia in the response to neurosteroids and mechanisms of injury
Male tissue has more cell death than female tissue after ischemia, and some neurosteroids only protect female cells.
research Topical and transdermal lipid-polymer hybrid nanoparticles (LPN): an integration in advancing dermatological treatments
Lipid-polymer hybrid nanoparticles show promise for skin treatments but need better formulation strategies.
research Single-cell transcriptomics defines keratinocyte differentiation in avian scutate scales
The research identified two types of keratinocytes in chicken scales: one for hard scales and another for soft skin, with similarities to human skin differentiation.
research The Function and Structure of the Skin
The skin protects the body, regulates temperature, senses touch, and makes vitamin D.
research Cutaneous Reactions to Drugs
Skin reactions are a common reason for emergency visits due to drug allergies, with some severe cases needing intensive care.
research Investigational medications in the treatment of alopecia
New treatments for hair loss are being developed using molecular biology.
research Increased expression of psoriasin (S100A7) and interleukin 17 (IL-17) in lesional skin in lichen planopilaris
S100A7 and IL-17 may contribute to inflammation in lichen planopilaris.
research Immune-Mediated Skin Reactions Induced by Recombinant Antibodies and Other TNF-Alpha Inhibitors
TNF-alpha inhibitors can cause various immune-related skin issues.