6 citations
,
April 2019 in “Journal of Pediatric Endocrinology and Metabolism” Metformin improved menstrual cycle regularity and signs of hyperandrogenism in adolescent girls with type 1 diabetes but did not improve blood sugar control.
1 citations
,
January 2017 in “Springer eBooks” Hair follicles are important for drug delivery through the skin, but better methods are needed to understand and improve this process.
October 2023 in “Research Square (Research Square)” Oxidative stress is linked to mild patchy alopecia areata.
82 citations
,
May 2016 in “Best Practice & Research in Clinical Obstetrics & Gynaecology” The conclusion is that managing androgen excess requires long-term treatment, including hormonal contraceptives and androgen blockers, with follow-up after six months.
61 citations
,
January 2015 in “Hormones” Liraglutide caused significant weight loss in some obese women with PCOS, especially those with severe obesity and insulin resistance.
33 citations
,
November 2012 in “Journal of The American Academy of Dermatology” FPHL common in Taiwanese women; risk factors include BMI, high glucose, early puberty, fewer childbirths, oral contraceptives, and UV exposure.
24 citations
,
September 2019 in “Journal of The American Academy of Dermatology” Low-dose oral minoxidil improved or stabilized hair loss in some patients, but higher doses may be needed for significant effects.
14 citations
,
December 2019 in “Iraqi Journal of Science” Iraqi women with PCOS often have higher testosterone levels and obesity.
8 citations
,
March 2010 in “Gynecological Endocrinology” Free Testosterone Index, bioavailable testosterone, and androstenedione are the most accurate for diagnosing excess male hormones in PCOS.
3 citations
,
August 2013 in “International journal of research in Ayurveda and pharmacy” Hairbac tablet and oil significantly improve hair texture, density, and reduce hair loss without side effects.
January 2023 in “International journal of medical science and health research” Anovulatory PCOS patients are younger with longer cycles and higher blood pressure and hormone levels.
December 2022 in “The Indian journal of chest diseases & allied sciences” Women with PCOS often have sleep problems, including sleep apnea, which are linked to obesity and depression.
October 2022 in “International journal of pharmaceutical sciences review and research” Hibiscus leaf extract is better for diabetes, and Eclipta alba bark extract is better for antioxidants.
October 2021 in “Turkderm” Hormonal imbalances, not insulin resistance or dyslipidemia, may be more important in causing acne in women over 25.
15 citations
,
January 2002 in “Gynecological endocrinology” Hormones affect skin aging and fat distribution, and treatments can help, but only minoxidil is proven for female hair loss.
4 citations
,
April 2011 in “International Journal of Radiation Biology” Radiation significantly slows down wound healing in mice.
1 citations
,
July 2005 in “Drugs and the pharmaceutical sciences” Targeting drugs to hair follicles can treat skin conditions, but reaching deep follicle areas is hard and needs more research.
39 citations
,
April 2011 in “Recent Patents on Drug Delivery & Formulation” Nanoemulsion-based drug delivery systems are versatile and have potential for treating various medical conditions and improving vaccines.
282 citations
,
October 2006 in “The Journal of Clinical Endocrinology and Metabolism” The Endocrine Society advised against routine testosterone therapy for women, citing a need for more research on long-term safety and a clear definition of androgen deficiency.
49 citations
,
October 2017 in “Nutrients” Equisetum debile extract, especially the ethyl acetate type, may be a promising natural ingredient for anti-hair loss products.
40 citations
,
August 2018 in “Skin appendage disorders” Some alternative treatments for hair loss might work, but more research is needed.
39 citations
,
May 2004 in “Clinics in Dermatology” The document concludes that treatment for cutaneous T-cell lymphoma should be customized to each patient's disease stage, balancing benefits and side effects, with no cure but many patients living long lives.
38 citations
,
February 2019 in “Clinical Interventions in Aging” Dutasteride more effectively treats hair loss than finasteride, but may increase risk of altered libido.
31 citations
,
January 2017 in “Advances in Experimental Medicine and Biology” Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.
29 citations
,
January 2009 in “Gynecological Endocrinology” Women with PCOS have higher levels of certain blood clotting factors, suggesting a greater risk of cardiovascular issues.
6 citations
,
July 2016 in “Gynecological Endocrinology” PSA levels are higher in women with PCOS, but FAI is a more accurate marker for diagnosis.
6 citations
,
April 2016 in “Journal of the Formosan Medical Association” Metformin improved insulin resistance and BMI in overweight Taiwanese women with PCOS, and a 2-hour insulin test may be a good screening tool.
5 citations
,
April 2014 in “Journal of Obstetrics and Gynaecology Research” Young Indian women with PCOS have a higher risk of heart disease, not linked to thyroid function but to higher levels of certain fats and homocysteine.
3 citations
,
March 2019 in “Post Reproductive Health” Testosterone replacement can help menopausal women with various symptoms, but should be used carefully and is not yet officially licensed in the UK for women.
1 citations
,
April 2021 in “Deneysel ve klinik tıp dergisi/Journal of experimental and clinical medicine” Women with PCOS have a higher risk of metabolic syndrome and need lifestyle changes and treatment.