research Skin and hair on-a-chip: in vitro skin models versus ex vivo tissue maintenance with dynamic perfusion
The Multi-Organ-Chip improves the growth and quality of skin and hair in the lab, potentially replacing animal testing.
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research New substrates for stem cell control
New materials help control stem cell growth and specialization for medical applications.
research Lupeol: an updated review utilizing AI-assisted predictive tools for enhanced therapeutic insights into lupeol’s potential for alopecia management
Lupeol shows promise for hair growth but needs better absorption and safety testing.
research Skin toxicity determined in vitro by three-dimensional, native-state histoculture.
This model can replace animal testing for quick, cost-effective skin toxicity tests.
research P56 Azathioprine-induced alopecia totalis and knuckle hyperpigmentation in a child with uveitis: test before you leap!
Monitor for early signs of azathioprine toxicity and check blood counts regularly.
research Acute dermal and ocular irritation testing of rice bran supercritical CO2 extract (RB-SCE) and 0.5% RB-SCE essence product
Rice bran extract caused moderate skin irritation but no eye irritation, while a diluted essence was not irritating to skin and only slightly to guinea pigs.
research 501 Next-generation in vitro testing: microfluidic models for aging, wound healing, and oral tissue analysis in safety, efficacy, and permeation studies
Microfluidic models improve testing for aging, wound healing, and oral tissue, reducing animal testing.
research Painful, Unexplained Peripheral Neuropathy? Think Thallium Toxicity
If someone has unexplained nerve pain and hair loss, doctors should check for thallium poisoning.
research Keratin‐based particles for protection and restoration of hair properties
Keratin-based particles safely improve hair strength, smoothness, and heat protection.
research Toxicological Studies on Procyanidin B-2 for Extern?al Application as a Hair Growing Agent
Procyanidin B-2 is safe to use on skin as a hair growth product.
research Azathioprine‐induced severe myelosuppression accompanied by massive hair loss and painful oral ulcer in an autoimmune hepatitis patient with NUDT15 minor variant: A case report
Genetic testing is crucial before giving azathioprine to avoid severe side effects.
research Next generation human skin constructs as advanced tools for drug development
Advanced human skin models improve drug development and could replace animal testing.
research Cepharanthine: a review of the antiviral potential of a Japanese-approved alopecia drug in COVID-19
Cepharanthine, a Japanese hair loss drug, shows promise as a COVID-19 treatment but needs more testing.
research The Effect of Nanoparticle-Incorporated Natural-Based Biomaterials towards Cells on Activated Pathways: A Systematic Review
Nanoparticles added to natural materials like cellulose and collagen can improve cell growth and wound healing, but more testing is needed to ensure they're safe and effective.
research Is Dutasteride a Therapeutic Alternative for Amyotrophic Lateral Sclerosis?
Dutasteride, usually used for prostate issues and hair loss, could potentially treat Amyotrophic Lateral Sclerosis (ALS) due to its neuroprotective, antioxidant, and anti-inflammatory properties, but more testing is needed.
research Cytotoxic Evaluation of Hair Relaxers and Straighteners Actives in Human-Derived Skin Cells
Hair relaxers and straighteners can be toxic to skin cells.
research 582 The Patent Landscape Analysis of Skin Bioinks for 3D Bioprinting
3D skin bioprinting, using skin bioinks like collagen and gelatin, is growing fast and could help treat wounds, burns, and skin cancers, as well as test cosmetics and drugs.
research The Comparison of In Vitro Photosensitizing Efficacy of Curcumin-Loaded Liposomes Following Photodynamic Therapy on Melanoma MUG-Mel2, Squamous Cell Carcinoma SCC-25, and Normal Keratinocyte HaCaT Cells
Liposomal curcumin improves skin cancer treatment effectiveness while sparing normal cells.
research Graphene Oxide–IPDI–Ag/ZnO@Hydroxypropyl Cellulose Nanocomposite Films for Biological Wound-Dressing Applications
The new nanocomposite films are stronger, protect against UV, speed up wound healing, and are antibacterial without being toxic.
research An osteopontin‐derived peptide inhibits human hair growth at least in part by decreasing fibroblast growth factor‐7 production in outer root sheath keratinocytes
FOL-005 peptide can reduce human hair growth by lowering FGF7 levels.
research Clinical Development of Topoisomerase-Interactive Drugs
New drugs targeting DNA enzymes show promise for cancer treatment but have side effects like immune system suppression and hair loss.
research Hair growth-promoting activity of components derived from sweet potato shochu
Sweet potato shochu oil and its components may effectively promote hair growth.
research From Russia with Love
Dr. Marina Kovalevsky and her daughter were hospitalized for suspected politically motivated thallium poisoning in Moscow.
research Consumption Perspectives of Traditional Cooked Corn-based Dough “Akpan” Wrapped in <i>Marantochloa cuspidata</i>, <i>Marantochloa purpurea</i> and <i>Marantochloa mannii</i> Leaves Collected in Togo: Nutritional Added Value and Potential Risks
Using these leaves to wrap corn-based foods in Togo is safe and boosts nutrition and preservation.
research Effects of a local commercial herbal cleanser on hair growth in Wistar rats
The herbal cleanser increased hair growth in rats without harming their skin.
research Cosmeceuticals in Dermatology
Cosmeceuticals may benefit skin health but need more research for efficacy and safety confirmation.
research Comprehension Testing for OTC Drug Labels: Goals, Methods, Target Population, and Testing Environment
The paper concludes that drug labels should be clear for all, especially for those with low literacy, and suggests aiming for high comprehension test passing rates with diverse test populations.
research Photostability and toxicity of finasteride, diclofenac and naproxen under simulating sunlight exposure: evaluation of the toxicity trend and of the packaging photoprotection
Sunlight exposure increases drug toxicity; amber glass best for protection.
research Toxicity of the pharmaceuticals finasteride and melengestrol acetate to benthic invertebrates
Finasteride harms invertebrates' survival and burial ability.
research Human Hair as a Testing Substrate in the Era of Precision Medicine: Potential Role of ‘Omics-Based Approaches
Human hair shows promise for non-invasive medical testing, but more research is needed to standardize its use.