research MP-09.08
The study found that different criteria led to different patient groups in the CombAT study compared to the MTOPS study.
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840-870 / 1000+ resultsresearch Synthesis, antiproliferative activity, acute toxicity and assessment of the antiandrogenic activities of new androstane derivatives
research Structural Characterization and Ligand Specific Protein Interactions of Androgen Receptor
SARM-induced changes in the androgen receptor are specific to each ligand and affect stability and protein interactions.
research OP-044 Midterm Results Following Percutaneous Rotational Thrombectomy for Acute Occlusions of Arteriovenous Access Grafts
The treatment successfully reopened blood flow in most patients and extended the use of their dialysis access with low risk.
research OP-048 The Relation Between Androgenetic Alopecia and Cardiovascular Atherosclerosis Measured via Carotid Intima-Media Thickness and the SYNTAX Score
Hair loss may indicate higher risk of heart disease.
research Gonadotropin releasing hormone agonist (nafarelin) test to differentiate gonadotropin deficiency from constitutionally delayed puberty in teen-age boys--a clinical research center study.
The nafarelin test can reliably distinguish between gonadotropin deficiency and delayed puberty in teenage boys.
research Selective androgen receptor modulators: a critical appraisal
SARMs show promise but need more evidence to prove they're better than traditional androgens.
research Epitestosterone—an endogenous antiandrogen?
Epitestosterone may act as a weak antiandrogen and can inhibit an enzyme involved in testosterone metabolism.
research α1-AR agonist induced piloerection protects against the development of traction alopecia
Using a certain drug on the skin can help prevent hair loss caused by pulling on the hair.
research A Top-Down Design Approach for Generating a Peptide PROTAC Drug Targeting Androgen Receptor for Androgenetic Alopecia Therapy
A new AI-driven method shows promise for treating hair loss with a peptide-based drug.
research Enriching Proteolysis Targeting Chimeras with a Second Modality: When Two Are Better Than One
Adding a second method to PROTACs could improve cancer treatment.
research Troponin I Biomarker for Cardiac Affection in Patients with Androgentic Aloepcia
Troponin I may help detect heart problems in people with Androgenetic Alopecia.
research ISID1116 – Novel androgen receptor degrader for androgenetic alopecia (AGA) application
research Evaluation of the therapeutic effects of AGA drugs by measuring finasteride, dutasteride, and dihydrotestosterone in hair
Finasteride and dutasteride effectively reduce DHT in hair, which may help evaluate their treatment success for hair loss.
research Polymer conjugated retinoids for controlled transdermal delivery
A new method allows for controlled, long-lasting delivery of retinoic acid through the skin with fewer side effects.
research Methodologic considerations in evaluating early clinical outcomes of GT20029 for androgenetic alopecia
GT20029 showed some hair growth improvement, but longer studies are needed for better results.
research The effect of intradermal botulinum toxin on androgenetic alopecia and its possible mechanism
Botulinum toxin injections may help treat hair loss by blocking harmful secretion in hair follicles.
research Reversal of alopecia areata, osteoporosis follow treatment with activation of Tgr5 in mice
Activating Tgr5 may help treat hair loss and bone loss.
research Botulinum toxin type A alleviates androgenetic alopecia by inhibiting apoptosis of dermal papilla cells via targeting circ_0135062/miR-506-3p/Bax axis
Botulinum toxin type A helps treat hair loss by stopping cell death in hair follicles through a process involving certain non-coding RNAs and a protein called Bax.
research Emerging medication for the treatment of male hypogonadism
New treatments for male hypogonadism are effective and should be personalized.
research Th,-e mechanistic insights into the application of retinoids and possible adjunct therapeutic treatment to androgenic alopecia
Retinoids may improve hair growth in androgenic alopecia when used with other treatments.
research Drug repurposing—a promising approach for patients with angina but non-obstructive coronary artery disease (ANOCA)
Using existing drugs for new purposes could be a cost-effective way to treat chest pain and non-clogged heart arteries, with some drugs for lung blood pressure showing promise but needing more testing.
research Effectiveness and Safety of Botulinum Toxin Type A in the Treatment of Androgenetic Alopecia
BTA safely and effectively treats hair loss, and works better with FNS.
research Is TrichoScan a new diagnostic method for diffuse hair loss?
TrichoScan effectively diagnoses different types of hair loss and is linked to low iron stores in patients.
research Antiandrogen therapy for androgenetic alopecia
Antiandrogen therapy helps treat genetic hair loss.
research EFFECTS OF ADRENOCORTICOTROPIC HORMONE ON BODY GROWTH, VISCERAL PROPORTIONS, AND WHITE BLOOD CELL COUNTS OF NORMAL AND HYPOPHYSECTOMIZED MALE RATS
Adrenocorticotropic hormone inhibits growth and affects body composition in male rats.
research Nonsteroidal tissue selective androgen receptor modulators: a promising class of clinical candidates
Selective androgen receptor modulators (SARMs) are a promising type of drug for various health conditions due to their targeted actions.
research Insights learned from L457(3.43)R, an activating mutant of the human lutropin receptor
The L457(3.43)R mutation in the human lutropin receptor causes increased activity and hormone insensitivity, leading to precocious puberty.
research Emerging pharmacotherapies for Androgenetic Alopecia
New treatments for hair loss focus on targeting specific causes to improve effectiveness and safety.
research Safety and efficacy of advanced and targeted acid α-glucosidase (AT-GAA) (ATB200/AT2221) in ERT-switch nonambulatory patients with Pompe disease: preliminary results from the ATB200-02 trial
The combination of tadalafil and finasteride improves urinary symptoms and erectile function in men with enlarged prostates.