September 2019 in “Journal of Investigative Dermatology” IL-17 and certain immune cells are linked to more severe alopecia areata.
21 citations
,
February 2017 in “PLoS ONE” RhoA helps skin stem cells grow, aiding wound healing.
12 citations
,
June 2020 in “The anatomical record” miR-203a-3p helps hair follicle stem cells become specialized by targeting Smad1.
Deleting Smad4 and PTEN genes in mice causes rapid, invasive forestomach cancer.
6 citations
,
May 2013 in “The Journal of Dermatology” Autoimmune reactions may cause both alopecia areata and HAM.
41 citations
,
January 2015 in “Development” Atoh1 expression can create new Merkel cells in the skin.
April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” Removing certain immune cells in mice causes their hair to enter the growth phase earlier than usual.
12 citations
,
May 2015 in “Molecular Medicine Reports” Troxerutin helps protect skin cells from oxidative stress and may be good for treating hair loss.
3 citations
,
November 2022 in “Molecules/Molecules online/Molecules annual” The substances improved hair regrowth and protected hair cells in humans and mice.
20 citations
,
November 2003 in “American Journal Of Pathology” Fibroblasts from healthy donors can prevent changes seen in recessive epidermolysis bullosa simplex.
1 citations
,
January 2020 in “Microscopy research” Researchers successfully grew hair follicle stem cells from mice and humans, which could be useful for tissue engineering and regenerative medicine.
February 2026 in “Biophysical Journal”
4 citations
,
July 2012 in “Genesis” The Megsin-Cre transgene is a new tool for genetic manipulation in the skin and upper digestive tract.
89 citations
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October 2003 in “Biology of the Cell” Galectin-1 helps in RNA processing in cell nuclei.
November 2022 in “Journal of Investigative Dermatology” ILC1-like cells can cause alopecia areata by themselves.
August 2023 in “Scientific reports” Human stem cells were turned into cells similar to those that help grow hair and showed potential for hair follicle formation.
4 citations
,
January 2014 in “The Journal of urology/The journal of urology” Kidney cancer cells without folliculin are more sensitive to radiation due to increased self-eating cell death.
June 2022 in “Research Square (Research Square)” Nestin-expressing cells turn into a specific type of skin cell in hair follicles during development and in adults.
5 citations
,
May 2020 in “Life science alliance” Removing integrin α3β1 from hair stem cells lowers skin tumor growth by affecting CCN2 protein levels.
184 citations
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November 2014 in “Developmental Cell” Hair follicle dermal stem cells are key for regenerating parts of the hair follicle and determining hair type.
April 2023 in “Journal of Investigative Dermatology” Proper cell death regulation is crucial for normal hair follicle regeneration and skin remodeling.
3 citations
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January 2011 in “生物医学研究杂志:英文版” A new mutation in the KRT86 gene causes monilethrix in a Han family.
12 citations
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February 2013 in “The Open Stem Cell Journal” DPSCs and SHED have great potential for medical treatments and tissue repair.
130 citations
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January 2000 in “Nature biotechnology”
April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” A specific group of early-stage melanocytes is reduced in vitiligo-affected skin, which may explain treatment resistance.
40 citations
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March 2019 in “Nature Communications” CRAC channels are crucial for the development and function of specialized immune cells, preventing severe inflammation and autoimmune diseases.
441 citations
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May 1996 in “Journal of Cell Science” Keratin 19 helps identify skin stem cells, with its presence varying by body location, age, and culture stage.
16 citations
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September 2016 in “Experimental Dermatology” Two-photon microscopy effectively tracks live stem cell activity in mouse skin with minimal harm and clear images.
April 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” Disrupting the Tsc2 gene in certain cells leads to thicker skin, larger hair, and changes in hair growth signaling, which can be partly reversed with specific treatment.
May 2017 in “Journal of The American Academy of Dermatology” LED light helps human hair root cells grow and prevents them from dying by activating specific growth pathways.