December 2012 in “Journal of Dermatological Science” Wnt/beta-catenin signaling in the skin helps fat cell development during hair growth and repair.
December 2017 in “bioRxiv (Cold Spring Harbor Laboratory)” Endoglin is important for proper hair growth cycles and stem cell activation in hair follicles.
66 citations
,
June 2001 in “Gastroenterology” The keratin 19 promoter effectively targets genes in specific epithelial cells in mice.
21 citations
,
March 2021 in “Frontiers in Neurology” The posterior cerebellum helps maintain balance by adapting to sensory inputs and self-motion.
1 citations
,
November 2025 in “Cell Death and Disease” Understanding how mesenchymal stem cells stay undifferentiated can improve their use in treating diseases.
403 citations
,
December 2018 in “Cell stem cell” Understanding phenotypic plasticity is crucial for developing effective cancer therapies.
305 citations
,
December 2000 in “The EMBO Journal” Inhibiting Bmp signaling disrupts hair growth and differentiation.
169 citations
,
February 2018 in “Immunity” Inactive stem cells in hair follicles and muscles can avoid detection by the immune system.
138 citations
,
July 2015 in “Clinical, Cosmetic and Investigational Dermatology” Eating less sugar, milk, and saturated fats and more vegetables and fish may help treat and prevent acne.
101 citations
,
November 2019 in “The Plant Cell” AtZP1 protein stops root hair growth in plants by blocking certain genes.
84 citations
,
December 2017 in “EMBO Reports” Circadian rhythms are crucial for stem cell function and tissue repair, and understanding them may improve aging and regeneration treatments.
81 citations
,
February 2019 in “Experimental & Molecular Medicine” PAK4 is crucial in cancer progression, brain development, and could be a therapeutic target, especially through the PAK4-CREB axis.
75 citations
,
June 2019 in “International Journal of Molecular Sciences” Costunolide may have multiple health benefits, including promoting hair growth and protecting against cancer and diabetes, but more research is needed.
62 citations
,
November 2009 in “Aging Cell” Hedgehog signaling helps keep hair follicle stem cells the same in both young and old human skin.
50 citations
,
September 2023 in “Biomarker Research” S100A6 is important for cell functions and can help diagnose and treat diseases.
44 citations
,
January 2023 in “New Phytologist” FER and TOR signaling help root hair growth in low temperature and low nitrate conditions.
41 citations
,
December 2018 in “Experimental Dermatology” Understanding how melanocyte stem cells work could lead to new treatments for hair graying and skin pigmentation disorders.
40 citations
,
March 2019 in “Nature Communications” CRAC channels are crucial for the development and function of specialized immune cells, preventing severe inflammation and autoimmune diseases.
36 citations
,
January 2021 in “Scientific Reports” Key genes and pathways, including Wnt, NF-Kappa, and JAK-STAT, are crucial for starting Pashmina fiber growth in goats.
28 citations
,
November 2019 in “Gene” The ITGB6 gene is important for tissue repair and hair growth, and mutations can lead to enamel defects and other health issues.
27 citations
,
March 2006 in “Molecular Plant Pathology” Legumes use flavonoids to start a process with rhizobia for nitrogen fixation, involving specific genes and proteins.
22 citations
,
August 1999 in “Mechanisms of Development” Pmg-1 and Pmg-2 are new genes important for skin and mammary gland development.
15 citations
,
August 2022 in “Journal of endocrinological investigation” Vitamin D and calcium are important for quick and effective skin wound healing.
15 citations
,
July 2013 in “Cell Reports” Indian Hedgehog helps control skin cell growth and protects against aggressive skin cancer.
14 citations
,
March 2022 in “Plant Cell & Environment” The protein AtRXR3 limits root hair growth in Arabidopsis, affecting phosphorus uptake.
12 citations
,
October 2023 in “International Journal of Molecular Sciences” Understanding how skin cells react to pressure can help diagnose and manage pressure-related skin disorders.
7 citations
,
July 2024 in “Current Issues in Molecular Biology” Understanding skin stem cells and their regulation is key to improving skin healing and treating disorders.
5 citations
,
June 2024 in “Free Radical Biology and Medicine” Maintaining natural oxygen levels is crucial for healthy skin cells and effective treatments.
5 citations
,
May 2023 in “Frontiers in Cell and Developmental Biology” Integrin α6 helps identify different neural crest cell types in the skin.
5 citations
,
July 2017 in “International journal of endocrinology and metabolism/International journal of endocrinology and metabolism.” Two siblings with a genetic mutation had a form of rickets that doesn't respond to vitamin D.