21 citations
,
September 2013 in “Current medicinal chemistry” HAC and BAC improve skin targeting and reduce diffusion without causing irritation.
33 citations
,
November 2019 in “Journal of Controlled Release” Microneedles with enhancer effectively promote hair growth and increase hair density.
149 citations
,
September 2017 in “Pharmaceutics” Pig skin is a good substitute for human skin to measure drug absorption, but differences in skin structure and enzymes across species must be considered.
3 citations
,
January 2004 in “Zhōnghuá yàoxué zázhì” Ethosomes improve skin absorption of finasteride more than other methods.
6 citations
,
May 2019 in “Journal of pharmaceutical sciences” Diffusion in artificial sebum is mainly influenced by molecular size and is much faster than in skin lipids.
32 citations
,
June 2024 in “Pharmaceutics” Nanoformulations improve drug delivery through the skin, reducing side effects and enhancing effectiveness.
35 citations
,
June 2017 in “Pharmaceutical research” Researchers developed a model that shows hair follicles increase skin absorption of caffeine by 20%.
1 citations
,
November 2022 in “Pharmaceutical research” The simulation showed that hypobaric pressure improves drug delivery through the skin, but stretching alone doesn't fully explain the increase.
12 citations
,
March 2012 in “ATLA. Alternatives to laboratory animals” Hair follicles significantly affect the skin absorption of some drugs.
1 citations
,
January 2007 Porcine skin is a good substitute for human skin in drug diffusion tests.
39 citations
,
August 2017 in “Colloids and Surfaces B: Biointerfaces” 50-nm nanoparticles are better at penetrating skin and targeting hair follicles for drug delivery than 100-nm ones.
1 citations
,
January 2023 in “Journal of pharmaceutical and biological sciences” Ethosomes are a promising way to deliver drugs through the skin.
365 citations
,
March 2021 in “Frontiers in Bioengineering and Biotechnology” Nanocarriers can improve drug delivery through the skin by overcoming barriers.
January 2026 in “Drug Delivery and Translational Research” Multicomponent crystals in microneedles improve drug delivery for hair loss treatment.
32 citations
,
September 2018 in “Journal of pharmaceutical sciences” The model better predicts how water-loving and fat-loving substances move through the skin by including tiny pores and hair follicle paths.
29 citations
,
September 2024 in “AAPS PharmSciTech” Transcutol® helps drugs penetrate the skin more effectively in various formulations.
9 citations
,
March 2024 in “Journal of Biomaterials Applications” Rizatriptan benzoate-loaded dissolving microneedles are effective and convenient for treating acute migraines.
21 citations
,
January 2012 in “Biological and Pharmaceutical Bulletin” Liposomes and iontophoresis effectively deliver protective enzymes into the skin against UV damage.
30 citations
,
March 2016 in “European Journal of Pharmaceutical Sciences” Optimized film improves finasteride skin absorption and treatment efficiency.
15 citations
,
February 2013 in “Pharmaceutical nanotechnology” Finasteride delivery through skin improved using invasomes and iontophoresis.
14 citations
,
March 2020 in “Scientific Reports” Using dual-frequency ultrasound with microbubbles can potentially improve the delivery of hair growth treatment through the skin and enhance hair growth.
February 2024 in “Research Square (Research Square)” Strat-M® membrane can effectively replace mouse skin for testing collagen peptide delivery.
151 citations
,
November 2018 in “International Journal of Pharmaceutics” Nanoparticles improve drug delivery through the skin but more research is needed on their long-term effects and skin penetration challenges.
151 citations
,
July 2011 in “Archives of Dermatological Research” Liposomal systems show promise for delivering drugs through the skin but face challenges like high costs and stability issues.
118 citations
,
May 2015 in “European journal of pharmaceutics and biopharmaceutics” The hydrogel with a 1:3 ratio of hydroxyethyl cellulose to hyaluronic acid is effective for delivering drugs through the skin to treat acne.
67 citations
,
January 2022 in “Theranostics” Advanced nanocarrier and microneedle drug delivery methods are more effective, safer, and less invasive for treating skin diseases.
60 citations
,
January 2023 in “Biomaterials Science” PLGA-based microneedles are promising for safe and effective skin delivery of drugs and vaccines.
42 citations
,
January 2021 in “Journal of Clinical Medicine” Microneedle arrays with nanotechnology show promise for painless drug delivery through the skin but need more research on safety and effectiveness.
41 citations
,
August 2024 in “Drug Delivery and Translational Research” 3D-printed microneedles improve drug delivery by being precise, cost-effective, and less invasive.
34 citations
,
July 2011 in “International journal of pharmaceutics” Ion-paired risedronate significantly increases skin penetration without irritation compared to risedronate alone.