211 citations
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June 2012 The skin is a complex barrier for drug penetration, but understanding its structure and interactions can improve drug delivery methods.
205 citations
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January 2005 in “Skin pharmacology and physiology” Liposomes and niosomes can help drugs penetrate the skin better.
182 citations
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January 2000 in “Drug Development Research” Ethosomal carriers improve drug delivery through the skin better than traditional methods.
122 citations
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November 2014 in “BMC Medicine” Oral testosterone therapy raises heart risk more than other methods.
117 citations
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November 2008 in “Drug Development and Industrial Pharmacy” Microemulsions can effectively deliver drugs through the skin but require careful ingredient selection to avoid irritation.
110 citations
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January 2014 in “Journal of Controlled Release” Phospholipid-coated nanoparticles penetrate hair follicles better than others, especially in pig ears.
84 citations
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July 2008 in “Aaps Pharmscitech” Ethosomes improve finasteride delivery through skin for hair loss treatment.
72 citations
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June 2019 in “International Journal of Cosmetic Science” 18β-glycyrrhetinic acid from licorice root is good for skin and hair treatments but has absorption challenges.
69 citations
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December 2015 in “Journal of Controlled Release” Nanocapsules can improve clobetasol delivery to hair follicles, reducing side effects.
68 citations
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March 2002 in “Journal of pharmaceutical sciences” Nonionic liposomes are the best for delivering genes to skin cells.
61 citations
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April 2023 in “Bioactive Materials” Microneedles are effective for painless drug delivery and promoting wound healing and tissue regeneration.
61 citations
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June 2022 in “Journal of Controlled Release” Dissolving microneedles show promise for delivering medication through the skin but face challenges like manufacturing complexity and regulatory hurdles.
61 citations
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May 2016 in “Scientific reports” The peptide IMT-P8 can effectively deliver proteins into the skin and cells for potential skin treatments.
58 citations
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November 2013 in “Journal of Innovative Optical Health Sciences” Multiphoton microscopy is a promising tool for detailed skin imaging and could improve patient care if its challenges are addressed.
48 citations
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February 2025 in “Nano-Micro Letters” Microneedles offer a promising, painless way to treat skin diseases but need improvements for better use.
48 citations
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January 2024 in “Frontiers in Pharmacology” Improving topical drug delivery involves overcoming skin barriers and using personalized dosing to enhance effectiveness.
40 citations
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January 2022 in “Frontiers in Chemistry” The patch speeds up deep wound healing.
29 citations
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September 2024 in “AAPS PharmSciTech” Transcutol® helps drugs penetrate the skin more effectively in various formulations.
29 citations
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April 2019 in “Lasers in Medical Science” Laser and minoxidil combo promotes better hair growth than minoxidil alone, safely.
26 citations
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January 2024 in “Gels” Nanoemulgels could effectively treat skin diseases and may replace or complement current therapies.
24 citations
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June 2018 in “Expert Review of Pharmacoeconomics & Outcomes Research” Microneedle technology is beneficial for drug delivery and could make vaccinations cheaper and more accessible.
22 citations
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September 2022 in “International Journal of Nanomedicine” CUR-loaded micelles improve skin delivery and effects of curcumin for pain and infections.
20 citations
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October 2023 in “Small” Microneedles show promise for treating hair loss, eye, and mouth diseases.
20 citations
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January 2007 in “Fertility and Sterility” A woman developed male traits from accidental contact with her husband's testosterone gel.
20 citations
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September 2006 in “The Veterinary clinics of North America. Small animal practice/Veterinary clinics of North America. Small animal practice” New drugs are improving treatment for hormone-related diseases in small pets.
19 citations
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July 2024 in “Drug Delivery” Polymer-based nanocarriers can improve acne treatment by delivering drugs through hair follicles more effectively.
19 citations
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May 2016 in “Clinical, cosmetic and investigational dermatology” FGF-2&D/P nanoparticles can help treat hair loss.
19 citations
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January 2000 in “Biological and Pharmaceutical Bulletin” Diclofenac salt delivery through skin varies based on the salt's counterions.
14 citations
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December 2024 in “Pharmaceutics” Hydrogel microneedles offer a promising, minimally invasive way to treat diseases like cancer and hair loss, but need improvements in strength and standardization.
14 citations
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February 2024 in “Pharmaceutics” We need to study how dissolving microneedles behave in the body to use them for medicine.