research Multifunctional NIR‐Triggered Nanozyme‐Based Microneedles for Synergistic Eradication of MRSA and Enhanced Wound Healing
The microneedles effectively kill MRSA and improve wound healing.
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930-960 / 1000+ resultsresearch A Smart Bandage Equipped with Miniaturized Needle Arrays and Wirelessly-Controlled Drug Delivery System for the Treatment of Chronic Wounds
The smart bandage improved healing in diabetic wounds better than standard treatments.
research Particle-based transcutaneous administration of HIV-1 p24 protein to human skin explants and targeting of epidermal antigen presenting cells
This method is effective for needle-free HIV-1 vaccination by activating immune responses in the skin.
research Emulgel Considered as Anovel Type of Dosage Form for Topical Application
Emulgels are effective for delivering skin medications due to their unique gel-emulsion mix.
research Follicular transport route – Research progress and future perspectives
Hair follicles help absorb and store topical compounds, aiding targeted drug delivery.
research Importance of Sebaceous Glands in Cutaneous Penetration of an Antiandrogen: Target Effect of Liposomes
Sebaceous glands in the skin play a key role in absorbing the antiandrogen drug RU 58841, especially when it's encapsulated in liposomes.
research Topical Carrier-Free Delivery of Finasteride and Peptides for Enhanced Hair Growth
A new topical method using peptides boosts hair growth effectively with less finasteride and fewer side effects.
research Drug Targeting to the Hair Follicles: A Cyclodextrin-Based Drug Delivery
research Tolerability, acceptability, and reproducibility of topical STAR particles in human subjects
STAR particles are safe, comfortable, and effective for enhancing drug delivery through the skin.
research Dendritic polyglycerol and N-isopropylacrylamide based thermoresponsive nanogels as smart carriers for controlled delivery of drugs through the hair follicle
Medium to larger nanogels effectively deliver drugs through hair follicles when heated.
research ROS-Scavenging CuxO Nanozyme-Functionalized Microneedle Patch for Androgenetic Alopecia Treatment
The microneedle patch with CuxO nanozymes effectively promotes hair growth for treating hair loss.
research Formulation and evaluation of dermatological products for topical delivery / by Mahima Manian
The study successfully developed and evaluated effective topical formulations for skin treatments.
research Biopharmaceutical characterization of carbopol gel for the dermal application of melatonin
The gel can effectively deliver melatonin through the skin.
research Drug delivery to hair follicles
Optimizing drug delivery to hair follicles is crucial for effective treatment.
research Topical absorption and systemic toxicity
Some chemicals absorbed through the skin can cause serious health problems.
research Unlocking Hair Follicles as Drug Reservoirs: Advances in Transfollicular Drug Delivery
This review discusses the potential of hair follicles as drug reservoirs, offering an alternative pathway for drug delivery that bypasses the stratum corneum barrier. It highlights recent advances in transfollicular drug delivery, emphasizing the effectiveness of nanoparticles, particularly those sized 300-400 nm, in enhancing drug delivery to hair follicles. Stimulus-responsive delivery systems, such as nanostructures activated by near-infrared light, have improved controlled and targeted drug release, which is beneficial for conditions like androgenic alopecia, acne, and psoriasis. The review also addresses methodological challenges and innovations in evaluating these delivery systems and explores the role of hair follicles in regenerative medicine, including the use of hair follicle organoids and biomaterial scaffolds. The goal is to establish hair follicles as strategic drug reservoirs that integrate topical therapy with regenerative medicine.
research Unlocking Hair Follicles as Drug Reservoirs: Advances in Transfollicular Drug Delivery
This review discusses the potential of hair follicles as drug reservoirs, offering an alternative pathway for drug delivery that bypasses the stratum corneum barrier. It highlights recent advances in transfollicular drug delivery, emphasizing the effectiveness of nanoparticles, particularly those sized 300-400 nm, in enhancing drug delivery to hair follicles. Stimulus-responsive delivery systems, such as nanostructures activated by near-infrared light, have improved controlled and targeted drug release, which is beneficial for conditions like androgenic alopecia, acne, and psoriasis. The review also addresses methodological challenges and innovations in evaluating these delivery systems and explores the role of hair follicles in regenerative medicine, including the use of hair follicle organoids and biomaterial scaffolds. The goal is to establish hair follicles as strategic drug reservoirs that integrate topical therapy with regenerative medicine.
research Follicular Targeting–A Promising Tool in Selective Dermatotherapy
Targeting hair follicles can improve skin treatments and reduce side effects.
research EMULGEL EMERGENT SYSTEMS: AT A GLANCE FOR TOPICAL DRUG DELIVERY
Emulgels are effective for delivering skin medications and cosmetics due to their easy application and controlled release.
research Herbal nano-formulations for topical delivery
Herbal nano-formulations show potential for effective skin delivery but need more research.
research Nanotechnology-based drug formulation and delivery systems for skin medical aesthetic dermatology: mechanisms, applications, and safety
Nanotechnology improves skin treatments by enhancing delivery and reducing side effects.
research Use of the skin sandwich technique to probe the role of the hair follicles in sonophoresis
Ultrasound increases skin permeability but blocks hair follicles.
research Core-shell and core-amphiphilic branched shell nanocarriers based on biodegradable hyperbranched polymers, as potential drug delivery systems
The new biodegradable nanocarriers safely and effectively deliver drugs into the skin.
research Transepidermal drug delivery: A new treatment option for areata alopecia?
Transepidermal drug delivery effectively treated areata alopecia with minimal side effects.
research The patch assay reconstitutes mature hair follicles by culture-expanded human cells
The patch assay can create mature hair follicles from human cells and may help in hair loss treatments.
research Effect of Rubbing Application on the Skin Permeation of Active Ingredients from Lotion and Cream
Rubbing skin increases absorption of water-soluble drugs from lotions and creams, but not oil-soluble drugs.
research Topical Administration of Drugs Incorporated in Carriers Containing Phospholipid Soft Vesicles for the Treatment of Skin Medical Conditions
Phospholipid soft vesicles improve topical drug delivery for better skin condition treatments.
research Targeting of Skin Antigen-Presenting Cells
Transcutaneous vaccination using nanoparticles can enhance immune responses and reduce basal cell carcinomas.
research Targeting to the hair follicles: Current status and potential
Hair follicles are promising targets for delivering drugs effectively.
research Follicular penetration of nano-sized particulate FA-PLGA and the dye RhBITC in dorsal dog and rat skin, and porcine ear skin as an in vitro model for the human integument
Hair follicles can effectively absorb nano-sized particles, making them potential targets for localized drug delivery.