research Venus trap in the mouse embryo reveals distinct molecular dynamics underlying specification of first embryonic lineages
Tmem50b and 2610305D13Rik genes play key roles in early mouse embryo development.
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750-780 / 1000+ resultsresearch Functional redundancy of Frizzled 3 and Frizzled 6 in planar cell polarity control of mouse hair follicles
Frizzled 3 and Frizzled 6 together control the orientation of mouse hair follicles.
research Non-viral delivery of the CRISPR/Cas system: DNAversusRNAversusRNP
RNA delivery is best for in-body use, while RNP delivery is good for outside-body use. Both methods are expected to greatly impact future treatments.
research Basal cell carcinomas acquire secondary mutations to overcome dormancy and progress from microscopic to macroscopic disease
Basal cell carcinomas need extra mutations to grow from small to large tumors.
research Lymphotoxin-β regulates periderm differentiation during embryonic skin development
Lymphotoxin-β is crucial for proper skin development in embryos.
research A pair of transmembrane receptors essential for the retention and pigmentation of hair
Bmpr2 and Acvr2a receptors are crucial for hair retention and color.
research Eavesdropping on the conversation between immune cells and the skin epithelium
Immune cells help keep skin healthy and repair it, but imbalance can cause disease.
research Overexpression of hepatoma-derived growth factor in melanocytes does not lead to oncogenic transformation
Overexpression of HDGF in melanocytes does not cause cancer.
research HSP90 Inhibition and Cellular Stress Elicits Phenotypic Plasticity in Hematopoietic Differentiation
Inhibiting HSP90 increases cell adaptability and survival under stress.
research Biomimetic Scaffolds—A Novel Approach to Three Dimensional Cell Culture Techniques for Potential Implementation in Tissue Engineering
Biomimetic scaffolds are better than traditional methods for growing cells and could help regenerate various tissues.
research Regulating Healthy Gender: Surgical Body Modification among Transgender and Cisgender Consumers
Transgender individuals face more barriers and less autonomy in surgical body modifications compared to cisgender individuals.
research Social rejection in minority groups and its impact on current and future mental health: a study in transgender people
Social rejection can harm long-term mental health in transgender individuals.
research (053) Multidisciplinary Treatment of Transgender Woman with Severe Gender Dysphoria and Comorbid Psychiatric Disorders - Case Report
The treatment helped a transgender woman stop drinking, improved her mental health, and reduced her gender dysphoria.
research Smad4-dependent desmoglein-4 expression contributes to hair follicle integrity
Smad4 is important for healthy hair follicles because it helps produce a protein needed for hair to stick together and grow.
research Caring for transgender populations: A primer for the dermatopathologist
Dermatopathologists must consider both birth sex and gender identity to accurately diagnose and treat transgender patients.
research Androgenetic Alopecia Incidence in Transgender and Gender Diverse Populations: A Retrospective Comparative Cohort Study
Transgender patients on masculinizing hormones have higher hair loss rates than cisgender women.
research Understanding the role of sex hormones in cancer for the transgender community
Hormone therapy affects cancer risks in transgender individuals differently than in cisgender people, and more research is needed to understand these risks and improve cancer screening guidelines.
research Facial minimally invasive aesthetic procedures and quality of life in transgender individuals: a prospective study
Facial aesthetic procedures improve quality of life for transgender individuals.
research 1336 The de novo DNA methyltransferase DNMT3A is required for epidermal homeostasis
DNMT3A is crucial for healthy skin and hair growth.
research Female Antiandrogens
Antiandrogens can treat female hormonal conditions, but environmental ones may harm reproductive health.
research Gender Reassignment
The conclusion is that certain surgeries can help people with gender dysphoria look more like their true gender and feel better.
research Preservation of Fertility in Transgender Men on Long-Term Testosterone Therapy: A Systematic Review of Oocyte Retrieval Outcomes During and After Exogenous Androgen Exposure
Oocyte retrieval is possible for transgender men on testosterone therapy without affecting fertility outcomes.
research Prevalence of Psoriasis and Perceived Association with Hormone Therapy in Transgender Adults
Psoriasis rates in transgender people are similar to the general population, but hormone therapy might affect it.
research Androgenetic Alopecia in Transgender Men: A Literature Review and Therapeutic Insights
Testosterone therapy in transgender men can lead to hair loss, with the risk increasing over time and influenced by family history.
research Adipocytes in Skin Health and Disease
Fat cells are important for healthy skin, hair growth, and healing, and changes in these cells can affect skin conditions and aging.
research Heme Oxygenase and the Skin in Health and Disease
HO-1 helps skin health and healing but can worsen melanoma; it's a potential treatment target for skin diseases.
research Higher androgen and estrogen output and less follicular atresia can be induced in healthy ovaries by culturing them with sera from PCOS patients: is PCOS really of intraovarian origin?
PCOS may be influenced by factors in the blood, not just the ovaries.
research Is there a role for 5α‐reductase inhibitors in transgender individuals?
5α-reductase inhibitors like finasteride may not be effective or safe for transgender individuals, and more research is needed.
research 61720 The effect of sublingual minoxidil on androgenetic alopecia in transgender individuals receiving testosterone for gender-affirmation: A 24-week single-centre double-blinded, randomized, placebo-controlled clinical trial
Sublingual minoxidil significantly improves hair growth in transgender individuals on testosterone therapy.
research Body composition and physical fitness in transgender versus cisgender individuals: a systematic review with meta-analysis
Transgender women have similar fitness to cisgender women, while transgender men have higher fat and lower strength than cisgender men; hormone therapy affects body composition and strength.