17 citations
,
May 2014 in “Cell transplantation” Genetically modified stem cells from human hair follicles can lower blood sugar and increase survival in diabetic mice.
7 citations
,
September 2013 in “Tissue engineering. Part A” Hair follicle stem cells can become motor neurons and reduce muscle loss after nerve injury.
July 2025 in “Journal of Investigative Dermatology” Wnt signaling helps regenerate hair follicles in wounds by reducing skin cell sensitivity to mechanical stress.
949 citations
,
January 2001 in “Cell” Adult mouse skin contains stem cells that can create new hair, skin, and oil glands.
136 citations
,
September 2019 in “Journal of Clinical Investigation” Dermal adipose tissue in mice can change and revert to help with skin health.
50 citations
,
February 2004 in “Genomics” A gene mutation causes lanceolate hair in rats by disrupting hair shaft integrity.
43 citations
,
October 2006 in “Journal of Cell Science” Keratin 10 end domains may increase skin cancer risk by reducing cell death.
42 citations
,
August 2012 in “Psychoneuroendocrinology” Finasteride reduces certain behaviors caused by D1-like receptor agonists but not by D2-like receptor agonists in mice.
39 citations
,
March 2009 in “Dermatology Online Journal” Understanding EGFR roles could lead to new hair loss treatments.
37 citations
,
December 2001 in “Journal of Investigative Dermatology” Leptin may play a role in hair growth and hair follicle health.
32 citations
,
February 2019 in “eLife” BMP signaling is essential for the development of touch domes.
32 citations
,
December 2017 in “Stem Cells Translational Medicine” We need to understand more about regeneration to improve human tissue healing.
24 citations
,
September 2014 in “PloS one” Thyroid hormone receptors are essential for hair growth and wound healing.
22 citations
,
June 2020 in “iScience” Sox21 is crucial for tooth development and enamel formation by preventing cells from changing into a different type.
8 citations
,
April 2016 in “Experimental dermatology” B6.Cg-Tyr c−2J Hr hr /J mice have a stronger delayed sunburn reaction and are good for UV research.
6 citations
,
September 2021 in “Autophagy” Autophagy prevents early aging and maintains lipid and pheromone balance in mouse glands.
5 citations
,
November 2013 in “Journal of Investigative Dermatology” The glucocorticoid receptor helps protect skin from tumors and other issues.
3 citations
,
September 2024 in “The FASEB Journal” Dermal white adipose tissue helps regulate hair growth, protect skin, and aid wound healing.
3 citations
,
February 2015 in “Mechanisms of development” Hormones and stretching both needed for nipple area skin growth in mice.
1 citations
,
July 2007 in “Journal of Investigative Dermatology” The mutation causes hairless mice due to mislocalized and dysfunctional HR protein.
September 2023 in “The FASEB journal” Foxn1 is important for fat development, metabolism, and wound healing in skin.
November 2019 in “SLAS technology” New findings suggest certain genes and microRNAs are crucial for wound healing, and innovative technologies like smart bandages and apps show promise in improving treatment.
March 2009 in “Dermatology Online Journal” Manipulating EGFR signaling may help treat hair loss and promote hair growth.
169 citations
,
January 2018 in “Cell Reports” Scientists grew hair follicles from mouse stem cells in a lab setting.
130 citations
,
March 2014 in “Proceedings of the National Academy of Sciences of the United States of America” Epidermal Wnt/β-catenin signaling controls fat cell formation and hair growth.
67 citations
,
June 2019 in “Proceedings of the National Academy of Sciences” A new 3D culture system helps grow and study mouse skin stem cells for a long time.
37 citations
,
August 2015 in “The Journal of Steroid Biochemistry and Molecular Biology” The vitamin D receptor can regulate genes and affect hair and hormone levels without its usual activator.
21 citations
,
October 2022 in “International Journal of Molecular Sciences” Quercitrin may help treat Alzheimer's by boosting brain cell signaling without causing tumors.
18 citations
,
August 2015 in “International Journal of Molecular Sciences” Ovine hair follicle stem cells can regenerate haired skin and may improve wool production.
11 citations
,
March 2016 in “Cell cycle/Cell cycle (Georgetown, Tex. Online)” Old hair follicles grew better when moved to a young environment.