4 citations
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May 2025 in “Cells” miR-370-3p slows sheep hair cell growth by blocking SMAD4.
2 citations
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June 2022 in “Molecules” Connarus semidecandrus Jack extract promotes hair growth and thickness, reduces prostate cancer cell growth, and could potentially be used as a treatment for hair loss.
New hair regrowth therapies show promise but need more research.
May 2025 in “Frontiers in Pharmacology” New treatments are needed for non-scarring alopecia due to current limitations.
November 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” Skin cells and certain hair follicle areas produce hemoglobin, which may help protect against oxidative stress like UV damage.
New treatments for hair loss, including a compound called "ALRV5XR", platelet-rich plasma, and Adult Stem Cell-based therapy, are showing promise, but more trials are needed for confirmation.
1 citations
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January 2018 in “Stem cell biology and regenerative medicine” DNA methylation is essential for skin and hair follicle development, and could be a target for treating skin diseases.
November 2023 in “International Journal of Medical Sciences” New regenerative medicine-based therapies for hair loss look promising but need more clinical validation.
November 2021 in “Current Otorhinolaryngology Reports” New treatments for hair loss could involve using stem cells and a process called the Wnt/beta-catenin pathway to stimulate hair growth.
January 2022 in “Stem cell biology and regenerative medicine” The document concludes that hair follicle regeneration involves various factors like stem cells, noncoding dsRNA, lymphatic vessels, growth factors, minoxidil, exosomes, and induced pluripotent stem cells.
3 citations
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April 2023 in “Frontiers in Pharmacology” ATP-sensitive K+ channel subunits, particularly Sur2A, play a significant role in various cancers.
August 2024 in “International Journal of Molecular Sciences” Androgenetic alopecia involves immune cell disruptions, especially increased CD4+ T cells around hair follicles.
2 citations
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July 2025 in “Frontiers in Veterinary Science” MicroRNAs and AI can improve cashmere goat hair quality and aid in hair disorder diagnosis.
44 citations
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June 2023 in “Cell Reports” IL-1 promotes fat cell growth in skin, while WNT inhibits it and encourages scar formation.
5 citations
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August 2025 in “Journal of Radiation Research” Understanding skin reactions to radiation has improved, helping to reduce injuries and prevent skin cancer.
2 citations
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September 2023 in “International journal of molecular sciences” Special proteins are important for skin balance, healing, and aging, and affect skin stem cells.
21 citations
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January 2023 in “International Journal of Molecular Sciences” S100A6 protein is linked to disease progression, especially in cancers.
124 citations
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July 2017 in “eLife” Type XVII collagen helps control skin cell growth and could be a target for anti-aging treatments.
122 citations
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April 2020 in “American Journal Of Pathology” Skin aging is a complex process influenced by various factors, leading to wrinkles and sagging, and should be considered a disease due to its health impacts.
87 citations
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March 2015 in “The EMBO Journal” Adult tissue stem cells can adapt and switch roles to help repair and maintain the body.
70 citations
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April 2020 in “Journal of Molecular Cell Biology” Organoid technology helps create mini-organs for studying diseases and testing drugs.
67 citations
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September 2001 in “American Journal Of Pathology” Inhibiting ODC can prevent UV-induced skin cancer.
54 citations
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January 2023 in “Signal Transduction and Targeted Therapy” New therapies are being developed that target integrin pathways to treat various diseases.
51 citations
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March 2022 in “Frontiers in Immunology” Alarmin cytokines are key in controlling skin immunity and inflammation.
51 citations
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May 1984 in “Journal of the American Academy of Dermatology” Benign follicular mucinosis involves immune cells attacking hair follicles.
45 citations
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August 2018 in “Stem Cells International” Stem cells, especially from fat tissue and Wharton's jelly, can potentially regenerate hair follicles and treat hair loss, but more research is needed to perfect the treatment.
44 citations
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January 2013 in “BMC Dermatology” TGFβ signaling prevents sebaceous gland cells from producing fats.
31 citations
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August 2021 in “Stem Cell Research & Therapy” The conclusion is that understanding how hair follicle stem cells live or die is important for maintaining healthy tissue and repairing injuries, and could help treat hair loss, but there are still challenges to overcome.
26 citations
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December 1999 in “Journal of Investigative Dermatology” Certain genes are linked to wool follicle structure and function, but not hair cycle regulation.
18 citations
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October 2021 in “Frontiers in Physiology” Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.