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research Characterization of Mouse Profilaggrin: Evidence for Nuclear Engulfment and Translocation of the Profilaggrin B-Domain during Epidermal Differentiation

25 citations , October 2002 in “The journal of investigative dermatology/Journal of investigative dermatology”

Mouse profilaggrin helps in skin cell differentiation and may be involved in calcium signaling.

research The New Keratin Nomenclature

14 citations , October 2006 in “Journal of Investigative Dermatology”

The keratin naming system was updated to include 54 genes, especially for hair-related keratins.

research Krt6a-Cre Transgenic Mice Direct LoxP-Mediated Recombination to the Companion Cell Layer of the Hair Follicle and Following Induction by Retinoic Acid to the Interfollicular Epidermis

10 citations , January 2004 in “Journal of Investigative Dermatology”

Krt6a-Cre transgenic mice help study gene effects on hair follicle development and tumor suppression.

research Comparative immunohistochemical analysis suggests a conserved role of EPS8L1 in epidermal and hair follicle barriers of mammals

1 citations , October 2023 in “PROTOPLASMA”

research Identification of a preferred substrate peptide for transglutaminase 3 and detection of in situ activity in skin and hair follicles

35 citations , July 2010 in “The FEBS journal”

The study found a specific peptide that helps detect TGase 3 activity in skin and hair follicles.

research Transglutaminase 5 Expression in Human Hair Follicle

28 citations , August 2005 in “Journal of Investigative Dermatology”

TG5 helps maintain hair follicle health, while TG3 aids in hair shaft development.

research Discrimination of Dysplastic Nevi from Common Melanocytic Nevi by Cellular and Molecular Criteria

41 citations , July 2016 in “Journal of Investigative Dermatology”

Dysplastic nevi have unique gene expressions, making them distinct from common melanocytic nevi.

research Hair shaft disorders in children – An update

12 citations , January 2023 in “Indian Dermatology Online Journal”

Diagnosing and managing children's hair shaft disorders is challenging but essential.

research Dynamics and Epigenetics of the Epidermal Differentiation Complex

February 2024 in “Epigenomes”

Epigenetic mechanisms control skin development by regulating gene expression.

research Spontaneous Quick Resolution of Uncombable Hair Syndrome-Like Disease

2 citations , October 2018 in “Skin appendage disorders”

A boy's hair that was frizzy and hard to comb returned to normal after 9 months, possibly due to genetic factors.

research The mouse keratin 6 isoforms are differentially expressed in the hair follicle, footpad, tongue and activated epidermis

75 citations , October 1999 in “Differentiation”

Mouse keratin 6 isoforms have different expression patterns in various tissues.

research Hair Keratin: Composition, Structure and Biogenesis

45 citations , January 1986

research Keratinization of outer root sheath cells is prevented by contact with inner root sheath of rat hair follicles

9 citations , July 2008 in “Archives of Dermatological Research”

research Hair Keratin

7 citations , January 1990

research Viral-associated trichodysplasia spinulosa: a case with electron microscopic and molecular detection of the trichodysplasia spinulosa-associated human polyomavirus

71 citations , January 2011 in “Journal of cutaneous pathology”

A rare skin condition was confirmed to be associated with a specific virus in a young girl.

research Hair, Wool, Quill, Nail, Claw, Hoof, and Horn

50 citations , January 1986

research Autosomal-Dominant Woolly Hair Resulting from Disruption of Keratin 74 (KRT74), a Potential Determinant of Human Hair Texture

97 citations , March 2010 in “The American Journal of Human Genetics”

A mutation in the KRT74 gene causes tightly curled hair.

research Type II Epithelial Keratin 6hf (K6hf) Is Expressed in the Companion Layer, Matrix, and Medulla in Anagen-Stage Hair Follicles

60 citations , December 2003 in “Journal of Investigative Dermatology”

K6hf is found in specific parts of hair follicles, nails, and tongue, and is linked to hair growth and structure.

research High-throughput T cell receptor sequencing identifies clonally expanded CD8+ T cell populations in alopecia areata

46 citations , October 2018 in “JCI insight”

CD8+ T cells are involved in alopecia areata and may cause disease relapse.

research Dynamic expression of Runx1 in skin affects hair structure

46 citations , August 2006 in “Mechanisms of Development”

Runx1 is crucial for proper hair structure and development.

research Alopecia in a Novel Mouse Model RCO3 Is Caused by mK6irs1 Deficiency

42 citations , September 2003 in “Journal of Investigative Dermatology”

A missing mK6irs1 gene causes hair loss in mice.

research Gsdma3 is required for hair follicle differentiation in mice

30 citations , October 2010 in “Biochemical and biophysical research communications”

The Gsdma3 gene is essential for normal hair development in mice.

research Transglutaminase 3: The Involvement in Epithelial Differentiation and Cancer

22 citations , August 2020 in “Cells”

TGM3 is important for skin and hair structure and may help diagnose cancer.

research Increased Susceptibility to Skin Carcinogenesis Associated with a Spontaneous Mouse Mutation in the Palmitoyl Transferase Zdhhc13 Gene

22 citations , December 2015 in “The journal of investigative dermatology/Journal of investigative dermatology”

A mouse gene mutation increases the risk of skin cancer.

research Progenitor cells expressing nestin, a neural crest stem cell marker, differentiate into outer root sheath keratinocytes

12 citations , July 2019 in “Veterinary Dermatology”

Nestin-expressing progenitor cells become outer root sheath keratinocytes.

research A pair of transmembrane receptors essential for the retention and pigmentation of hair

11 citations , May 2012 in “Genesis”

Bmpr2 and Acvr2a receptors are crucial for hair retention and color.

research Transcriptome Profiling and Differential Gene Expression in Canine Microdissected Anagen and Telogen Hair Follicles and Interfollicular Epidermis

7 citations , August 2020 in “Genes”

Different genes are active in dogs' hair growth and skin, similar to humans, which helps understand dog skin and hair diseases and can relate to human conditions.

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