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(1R,2S)-4-(2-Cyano-Cyclohexyl-Oxy)-2-Trifluoromethyl-Benzonitrile, A Potent Androgen Receptor Antagonist For Stimulating Hair Growth And Reducing Sebum Production

research (1R,2S)-4-(2-Cyano-cyclohexyl-oxy)-2-trifluoromethyl-benzonitrile, a potent androgen receptor antagonist for stimulating hair growth and reducing sebum production

14 citations , August 2007 in “Bioorganic & Medicinal Chemistry Letters”

The compound (1R,2S)-4-(2-Cyano-cyclohexyl-oxy)-2-trifluoromethyl-benzonitrile can stimulate hair growth and reduce oil production when applied topically.

Nonsteroidal Inhibitors of Human Type I Steroid 5α-Reductase

research Nonsteroidal inhibitors of human type I steroid 5-.alpha.-reductase

89 citations , February 1993 in “Journal of Medicinal Chemistry”

New compounds called benzoquinolinones may treat conditions linked to excess DHT.

research Mixture effects of endocrine disrupting compounds in vitro

108 citations , January 2010 in “International Journal of Andrology”

Weak endocrine disruptors in mixtures can have significant effects and should be considered in risk assessments.

Bioactivity Guided Isolation and Characterization of the Phytoconstituents from Tridax Procumbens

research Bioactivity guided isolation and characterization of the phytoconstituents from the Tridax procumbens

9 citations , February 2011 in “Revista Brasileira de Farmacognosia”

Tridax procumbens plant parts boost immune response in mice.

research Sacituzumab Govitecan-Hziy (Trodelvy™)

3 citations , April 2021 in “Oncology Times”

Trodelvy™ helped some patients with advanced breast cancer, but had side effects.

research Natural Product-InspiredBis(trifluoromethyl) PhenylHydroxycinnamate Derivatives as Promising Nonsteroidal Inhibitorsof Human Steroid 5α-Reductase Type-1: Synthesis, InVitro, and In Silico Studies

August 2025 in “OPAL (Open@LaTrobe) (La Trobe University)”

Certain hydroxycinnamate derivatives may effectively inhibit enzymes linked to hair loss with low toxicity.

research From Weed to Wonder: Exploring the Multifaceted Pharmacological Actions of Tridax procumbens Linn.

December 2025 in “Zenodo (CERN European Organization for Nuclear Research)”

Tridax procumbens is a promising herb for developing safe, affordable plant-based medicines.

research Acute And Sub Chronic Toxicity Of Tridax Procumbens In Experimental Animals

17 citations , January 2012 in “IOSR Journal of Environmental Science Toxicology and Food Technology”

High doses of Tridax procumbens extract can be toxic, affecting liver and kidneys.

research Die kontrazeptive Betreuung androgenisierter Frauen mit einem niedrig dosierten cyproteronacetathaltigen Einphasenpräparat

18 citations , September 1979 in “DMW - Deutsche Medizinische Wochenschrift”

Diane is effective for treating acne, seborrhoea, androgenic alopecia, and mild hirsutism in women.

research From Weed to Wonder: Exploring the Multifaceted Pharmacological Actions of Tridax procumbens Linn.

December 2025 in “Zenodo (CERN European Organization for Nuclear Research)”

Tridax procumbens is a promising herb for developing safe, affordable plant-based medicines.

research Estrogenic Potential of 2-Alkyl-4-(thio)chromenone 6-O-Sulfamates: Potent Inhibitors of Human Steroid Sulfatase

37 citations , September 2003 in “Journal of Medicinal Chemistry”

A substance called Compound 2g can strongly block STS (a hormone-related enzyme) without affecting estrogen levels, making it potentially good for treating breast cancer.

research Trichoblastic Carcinoma

2 citations , July 2001 in “Dermatologic Surgery”

Trichoblastic carcinoma may be a distinct type of skin cancer different from basal cell carcinoma.

Synthesis and In Vitro Study of 17β-[N-Ureylene-N,N′-Disubstituted]-4-Methyl-4-Aza-5α-Androstan-3-Ones as Selective Inhibitors of Type I 5α-Reductase

research Synthesis and in vitro study of 17β-[N-ureylene-N,N′-disubstituted]-4-methyl-4-aza-5α-androstan-3-ones as selective inhibitors of type I 5α-reductase

5 citations , February 1997 in “Bioorganic & Medicinal Chemistry”

New compounds were made that effectively block a specific enzyme related to androgen conditions.

Validated HPTLC Method for the Simultaneous Determination of Alfuzosin, Terazosin, Prazosin, Doxazosin, and Finasteride in Pharmaceutical Formulations

research Validated HPTLC method for the simultaneous determination of alfuzosin, terazosin, prazosin, doxazosin and finasteride in pharmaceutical formulations

26 citations , July 2014 in “Analytical Chemistry Research”

Method can accurately measure five BPH drugs at once.

research Synthesis, Crystal Structure and Supramolecular Features of Novel 2,4-Diaminopyrimidine Salts

5 citations , January 2024 in “Crystals”

The salts have diverse molecular packing with significant hydrogen interactions.

research A Review of Medicinal Uses and Pharmacological Activities of Tridax Procumbens (L.)

54 citations , January 2018 in “Journal of Plant Studies”

Tridax procumbens may be a safe, affordable treatment for some health issues.

research Dual Tumors — Trichoadenoma of Nikolowski and Melanocytic Naevi

September 2022 in “Journal of medical sciences and health”

A person had two different benign skin tumors, a trichoadenoma and melanocytic naevi, at the same time but in different places on the face.

$Synthesis and Structural Characterization of a New Dinuclear Platinum(III) Complex, [Pt2Cl4(NH3)2{μ-HN=C(O)Bu^t}2]$

research Synthesis and structural characterization of a new dinuclear platinum(III) complex, [Pt₂Cl₄(NH₃)₂{μ-HN=C(O)Bu^t}₂]

2 citations , November 2022 in “Acta crystallographica. Section B, Structural science, crystal engineering and materials./Acta crystallographica. Section B, Structural science, crystal engineering and materials”

A new platinum complex was made and studied, which might help fight cancer better.

Verification of the Major Metabolic Oxidation Path for the Naphthoyl Group in Chemoattractant Receptor-Homologous Molecule Expressed on Th2 Cells (CRTh2) Antagonist 2-(2-(1-Naphthoyl)-8-fluoro-3,4-dihydro-1H-pyrido[4,3-b]indol-5(2H)-yl)acetic Acid (Setipiprant/ACT-129968)

research Verification of the Major Metabolic Oxidation Path for the Naphthoyl Group in Chemoattractant Receptor-Homologous Molecule Expressed on Th2 Cells (CRTh2) Antagonist 2-(2-(1-Naphthoyl)-8-fluoro-3,4-dihydro-1H-pyrido[4,3-b]indol-5(2H)-yl)acetic Acid (Setipiprant/ACT-129968)

6 citations , September 2015 in “Journal of Medicinal Chemistry”

The document confirms the structures of major metabolites of the CRTh2 antagonist Setipiprant and identifies minor metabolites.

research Novel 5α-Reductase Inhibitors: Synthesis, Structure−Activity Studies, and Pharmacokinetic Profile of Phenoxybenzoylphenyl Acetic Acids

18 citations , December 2005 in “Journal of Medicinal Chemistry”

A brominated phenoxy compound effectively inhibits a human enzyme and shows potential for clinical use.

Green Fabrication of ZnO Nanoparticles from Tridax Procumbens Leaf Extract: Antimicrobial and Cytotoxic Evaluation on MCF7 and A549 Cells

research Green Fabrication of ZnO Nanoparticles from Tridax procumbens leaf extract: Antimicrobial and Cytotoxic Evaluation on MCF7 and A549 Cells

January 2026 in “Journal of Emerging Technologies and Innovative Research”

Zinc oxide nanoparticles made from Tridax procumbens leaves show strong antibacterial and anticancer effects.

research [Study of gonadal hormone drugs in blocking filovirus entry of cells in vitro].

5 citations , December 2015 in “PubMed”

Some gonadal hormone drugs can block filovirus entry into cells.

research Clobetasol/minoxidil

February 2023 in “Reactions Weekly”

research Finasteride

June 2014 in “Reactions Weekly”

research Finasteride

January 2014 in “Reactions Weekly”

research Finasteride

August 2011 in “Reactions Weekly”

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