research The TFIID subunit TAF4 regulates keratinocyte proliferation and has cell-autonomous and non-cell-autonomous tumour suppressor activity in mouse epidermis
TAF4 is important for skin cell growth and helps prevent skin cancer in mice.
Search
for
Sort by
Research
660-690 / 1000+ results 
research Inducing hair follicle neogenesis with secreted proteins enriched in embryonic skin
Three specific proteins can turn adult skin cells into hair-growing cells, suggesting a new hair loss treatment.
research Cell Cycle Regulation and Regeneration
Mice that can regenerate tissue have cells that pause in the cell cycle, which is important for healing, similar to axolotls.
research Essential Role of Polarity Protein Par3 for Epidermal Homeostasis through Regulation of Barrier Function, Keratinocyte Differentiation, and Stem Cell Maintenance
The protein Par3 is crucial for healthy skin, affecting the skin barrier, cell differentiation, and stem cell maintenance.
research Esrp1-Regulated Splicing of Arhgef11 Isoforms Is Required for Epithelial Tight Junction Integrity
The study concluded that specific proteins are necessary to maintain the structure that holds epithelial cells tightly together.
research Optimization of ultrasound-assisted extraction of bioactive compounds from Carthamus caeruleus L. rhizome: Integrating central composite design, Gaussian process regression, and multi-objective Grey Wolf optimization approaches
Optimal conditions for extracting beneficial compounds from Carthamus caeruleus L. rhizomes were identified, improving efficiency.
research Critical Role of ATP-P2X7 Axis in UV-Induced Melanogenesis
ATP increases melanin production in skin after UV exposure, with the P2X7 receptor being crucial for this process.
research Analysis of Dermal Papilla Cell Interactome Using STRING Database to Profile the ex Vivo Hair Growth Inhibition Effect of a Vinca Alkaloid Drug, Colchicine
Colchicine can inhibit hair growth by affecting cell activity and protein expression in hair follicles.
research Alopecia areata presenting in 2 kidney-pancreas transplant recipients taking cyclosporine
Two transplant patients on cyclosporine unexpectedly developed hair loss.
research Japan Strengthens Regenerative Medicine Oversight
Japan improved its regulation of regenerative medicine to ensure safety and prevent unproven treatments.
research Topical use of systemic drugs in dermatology: A comprehensive review
Using systemic drugs as creams for skin conditions shows promise, but more research is needed to confirm their effectiveness and safety.
research Adipocyte-myofibroblast transition as a possible pathophysiological step in androgenetic alopecia
AMT may cause hair loss and changing dWAT activity could help treat it.
research Expression of 11β-hydroxysteroid dehydrogenase type 1 in visceral and subcutaneous adipose tissues of patients with polycystic ovary syndrome is associated with adiposity
Increased HSD11B1 enzyme expression is linked to higher body fat and insulin resistance.
research Identification of dual-purpose therapeutic targets implicated in aging and glioblastoma multiforme using PandaOmics - an AI-enabled biological target discovery platform
CNGA3, GLUD1, and SIRT1 are promising targets for treating aging and glioblastoma.
research A Cu@ZIF-8 encapsulated antibacterial and angiogenic microneedle array for promoting wound healing
The microneedle arrays effectively promote wound healing and have potential for clinical use.
research Structural and biochemical changes underlying a keratoderma-like phenotype in mice lacking suprabasal AP1 transcription factor function
Inhibiting AP1 in mice skin causes structural changes and weakens the skin barrier.
research Engineering Cell‐Derived Matrices: From 3D Models to Advanced Personalized Therapies
3D cell-derived matrices improve tissue regeneration and disease modeling.
research High-confidence cancer patient stratification through multiomics investigation of DNA repair disorders
CEP135 may predict cancer outcomes, and targeting PLK1 could help treat certain sarcomas.
research Investigation of a non-invasive method of assessing the equine circadian clock using hair follicle cells
RNA from horse hair follicles can track circadian rhythms non-invasively.
research Platelet-Therapeutics to Improve Tissue Regeneration and Wound Healing—Physiological Background and Methods of Preparation
Platelet-rich treatments can help improve wound healing and tissue repair.
research Age-Related Changes in Female Scalp Dermal Sheath and Dermal Fibroblasts: How the Hair Follicle Environment Impacts Hair Aging
Aging causes changes in the scalp that can affect hair growth and lead to older-looking hair in women.
research Adaptive minirhizotron for pepper roots observation and its installation based on root system architecture traits
The new microrhizotron tool effectively observes and measures pepper plant roots non-destructively.
research Estimation methods for human circadian phase by use of peripheral tissues
New method uses hair follicle cells to estimate human body clock phase, potentially improving sleep disorder diagnosis.
research A Unique Expression of Keratin 14 in a Subset of Trophoblast Cells
Keratin 14 is uniquely found in a specific group of placental cells.
research Procyanidin Oligomers Counteract TGF-β1- and TGF-β2-Induced Apoptosis in Hair Epithelial Cells: An Insight into Their Mechanisms
Procyanidin compounds from apples and barley promote hair growth and prevent hair cell death.
research Targeted expression of SV40 T antigen in the hair follicle of transgenic mice produces an aberrant hair phenotype
SV40 T antigen in hair follicles causes abnormal hair and health issues in mice.
research Non-hemorrhage-related adverse effects of rivaroxaban
Rivaroxaban can cause liver injury, allergic reactions, blood vessel inflammation, and hair loss, but these side effects are rare.
research Valproic Acid–induced Hair‐texture Changes in a White Woman
Valproic acid can cause reversible hair curling and persistent hair thinning.
research An ovarian Leydig cell tumor of ultrasound negative in a postmenopausal woman with hirsutism and hyperandrogenism
A postmenopausal woman's hirsutism and high testosterone levels improved after surgery for an ovarian tumor not seen on ultrasound.
research Altered expression of intracellular Toll-like receptors in peripheral blood mononuclear cells from patients with alopecia areata
Increased Toll-like receptors in blood cells may contribute to alopecia areata and could be a target for new treatments.