211 citations
,
October 2001 in “The FASEB Journal” Noggin is necessary to start the hair growth phase in skin after birth.
July 2025 in “Journal of Investigative Dermatology” Secreted inhibitors of Wnt and IGF signaling control hair and tooth development, creating species-specific patterns.
December 2024 in “Tissue and Cell” A new method helps detect androgen receptor movement in cells, aiding research on hair loss treatments.
168 citations
,
August 2000 in “American Journal of Pathology” Fibromodulin might help reduce scarring if increased in adult wounds like in fetal skin that heals without scars.
26 citations
,
December 1999 in “Journal of Investigative Dermatology” Certain genes are linked to wool follicle structure and function, but not hair cycle regulation.
April 1996 in “Journal of Dermatological Science” 4 citations
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October 2004 in “Humana Press eBooks” Epidermal growth factor stops hair follicle formation in developing mouse skin.
5 citations
,
February 2014 in “PloS one” Eyelid cells share signaling components but differ in pathway activity.
82 citations
,
February 2017 in “Cold Spring Harbor Perspectives in Biology” The TGF-β family helps control how cells change and move, affecting skin, hair, and organ development.
November 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” The study found markers indicating that cells responsible for hair color are differentiating in specific areas of the hair follicle.
55 citations
,
February 1975 in “Journal of Cutaneous Pathology” Dermal cell activity increases during hair growth in rats.
384 citations
,
June 2005 in “Genes & development” β-catenin is essential for stem cell activation and proliferation in hair follicles.
10 citations
,
January 2016 in “PLOS ONE” Researchers found 44 proteins that change during different hair growth stages and may be important for hair follicle function.
40 citations
,
May 2005 in “Journal of Cell Science” Truncated LTBP-1 disrupts TGF-β signaling, affecting hair growth.
January 2025 in “International Journal of Genomics” Three genes, BMP4, POSTN, and WNT5A, may help treat keloids.
215 citations
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November 2000 in “Journal of Investigative Dermatology” The system allows precise control of gene expression in mouse skin, useful for studying skin biology.
2 citations
,
December 2022 in “Scientific Data” The study maps how genes are regulated during mouse hair growth.
112 citations
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May 2020 in “Nature Communications” Adult fibroblasts help heart cells mature and improve heart function.
April 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” Researchers developed a method to grow human hair follicles using 3D-printed skin models and modified cells.
1 citations
,
January 2014 in “Chinese Journal of Traditional Medical Traumatology & Orthopedics” The methods can provide high-quality cells for creating artificial hair follicles, blood vessels, and skin.
22 citations
,
July 1990 in “Acta Dermato Venereologica” High levels of testosterone and dihydrotestosterone inhibit hair cell growth, while high levels of estradiol promote it.
176 citations
,
January 2013 in “Proceedings of the National Academy of Sciences” BMP and Wnt signaling balance controls hair follicle stem cell activity and hair growth.
22 citations
,
October 2012 in “Cell Transplantation” Cells treated with Wnt-10b can grow hair after being transplanted into mice.
11 citations
,
June 2012 in “Acta histochemica” Mice with a Gsdma3 gene mutation have thicker skin and longer hair follicle openings due to increased β-catenin levels.
January 1998 in “Differentiation” Basonuclin is crucial for hair follicle development and cycling in mice.
16 citations
,
February 2007 in “Plastic and Reconstructive Surgery” Keratinocytes show more TGF-β system activity and collagen production as they age, which might affect wound scarring.
February 2026 in “Journal of Cellular Physiology” TGF-β3 controls stem cell growth and development, varying by cell type and conditions.
6 citations
,
October 2020 in “Journal of Cellular and Molecular Medicine” 3D culture helps maintain hair growth cells better than 2D culture and identifies key genes for potential hair loss treatments.
2 citations
,
November 2006 in “Pump Industry Analyst” Pilomatricomas don't follow the usual hair follicle cell differentiation process.
8 citations
,
April 2009 in “International journal of oncology” Hair follicle cells resist turning into skin cells.