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Did you mean Tumor Necrosis Factor?

GlossaryTumor Necrosis Factor

protein involved in inflammation and immune system regulation

Tumor Necrosis Factor (TNF), also known as TNF-alpha, is a protein produced by the immune system that plays a crucial role in inflammation and the body's response to infection. It helps regulate immune cells, but excessive TNF can lead to chronic inflammatory diseases such as rheumatoid arthritis and psoriasis.

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research Tumor Necrosis Factor-α and Interleukin-1 Antagonists Alleviate Inflammatory Skin Changes Associated with Epidermal Growth Factor Receptor Antibody Therapy in Mice

53 citations , July 2009 in “Cancer Research”

Blocking certain proteins can reduce skin inflammation caused by cancer treatment.

research Data from Tumor Necrosis Factor-α and Interleukin-1 Antagonists Alleviate Inflammatory Skin Changes Associated with Epidermal Growth Factor Receptor Antibody Therapy in Mice

March 2023

TNFα and interleukin-1 blockers reduce skin inflammation from EGFR antibody therapy.

research Data from Tumor Necrosis Factor-α and Interleukin-1 Antagonists Alleviate Inflammatory Skin Changes Associated with Epidermal Growth Factor Receptor Antibody Therapy in Mice

March 2023

TNFα and interleukin-1 blockers reduce skin inflammation from EGFR antibody therapy.

research Expression of transforming growth factor-β_1 and tumor necrosis factor-α in mice with radiationinduced pulmonary injury

January 2010 in “Zhongguo xiandai yixue/Zhongguo xiandai yixue zazhi”

TGF-β1 and TNF-α contribute to lung damage after radiation.

Microinjury-Induced Tumor Necrosis Factor-Alpha Surge Stimulates Hair Regeneration in Mice

research Microinjury-Induced Tumor Necrosis Factor-α Surge Stimulates Hair Regeneration in Mice

January 2023 in “Skin Pharmacology and Physiology”

Minor injuries to hair follicles can stimulate hair growth in mice by increasing a specific protein.

research Supplementary material for: Microinjury-Induced Tumor Necrosis Factor-α Surge Stimulates Hair Regeneration in Mice

January 2023 in “Figshare”

Minor skin injuries can boost hair growth by increasing TNF-α.

research The Tumor Necrosis Factor-α Level in Platelet-Rich Plasma Might Be Associated with Treatment Outcome in Patients with Interstitial Cystitis/Bladder Pain Syndrome or Recurrent Urinary Tract Infection

8 citations , December 2023 in “International Journal of Molecular Sciences”

Lower TNF-α levels in PRP may predict better treatment outcomes for bladder conditions.

research Alopesi areata hastalarında serum interferon-gama, tümör nekrozis faktör-alfa, interlökin-13, interlökin-17 ve transforming growth faktör-beta düzeylerinin değerlendirilmesi

January 2016

Atopy and altered T cell functions contribute to Alopecia Areata.

research Cytokines and growth factors influence hair growth in vitro. Possible implications for the pathogenesis and treatment of alopecia areata

91 citations , March 1996 in “Archives of Dermatological Research”

Certain cytokines and growth factors can inhibit hair growth and may affect alopecia areata.

Pinus Thunbergii Bark Extract Rich in Flavonoids Promotes Hair Growth in Dorsal Skin by Regulating Inflammatory Cytokines and Increasing Growth Factors in Mice

research Pinus thunbergii bark extract rich in flavonoids promotes hair growth in dorsal skin by regulating inflammatory cytokines and increasing growth factors in mice

5 citations , January 2022 in “Molecular Medicine Reports”

Pine bark extract helps mice grow hair by reducing inflammation and boosting growth factors.

Collagen Hydrolysate from Mozambique Tilapia Scales Improves Hair and Skin Health

research Collagen Hydrolysate from the Scales of Mozambique Tilapia (Oreochromis mossambicus) Improve Hair and Skin Health by Alleviating Oxidative Stress and Inflammation and Promoting Hair Growth and Extracellular Matrix Factors

2 citations , August 2023 in “Marine drugs”

Collagen from tilapia scales may improve hair and skin health by reducing stress and inflammation and encouraging hair growth.

research Narrow-band red LED light promotes mouse hair growth through paracrine growth factors from dermal papilla

23 citations , September 2011 in “Journal of Dermatological Science”

Red LED light helps mouse hair grow by increasing growth factors from skin cells.

research 510 Enhancing hair follicle growth: investigating the synergistic effects of ursolic and shikimic acid through in vitro testing on dermal papilla cells

November 2024 in “Journal of Investigative Dermatology”

Ursolic and shikimic acid together boost hair growth better than alone.

research Effect of Ficus carica leaf extract on the gene expression of selected factors in HaCaT cells

16 citations , April 2017 in “Journal of Cosmetic Dermatology”

Ficus carica leaf extract may help treat skin disorders by reducing inflammation and androgen effects in skin cells.

research Experiment on the effect of Artemisia sieversiana extract on hair loss prevention and cell growth

1 citations , March 2022 in “Daehanhanuihakoeji”

Artemisia sieversiana extract may help prevent hair loss and promote hair growth.

research Effects of oleanolic acid on hair growth in mouse dorsal skin mediated via regulation of inflammatory cytokines

March 2023 in “Journal of Applied Biomedicine”

Oleanolic acid improved hair growth in mice by affecting hair growth pathways and reducing inflammation.

research Identification of clustered cells in human hair follicle responsible for MMP‐9 gelatinolytic activity: consequences for the regulation of hair growth

27 citations , June 2001 in “International Journal of Dermatology”

MMP-9 increase in hair follicles may lead to hair loss.

research Aqueous Dispersion of Unmodified Fullerene C60: Stimulation of Hair Growth and Study of a New Molecular Target for Interaction

September 2025 in “International Journal of Molecular Sciences”

Unmodified fullerene C60 promotes hair growth and may help treat hair loss.

research Hair Growth Promoting Effect of Thuja orientalis Ethanol Extracts on Hair Loss-induced DBA1J Mice

1 citations , January 2004 in “Journal of Physiology & Pathology in Korean Medicine”

Thuja orientalis extract significantly promotes hair growth in mice with hair loss.

research 698 Effect of lithocholic acid as a ligand of vitamin D receptor on hair growth in alopecia

April 2016 in “Journal of Investigative Dermatology”

Lithocholic acid helps hair growth and regeneration in alopecia by activating vitamin D receptors.

Alopecia Induced by Tumor Necrosis Factor-Alpha Antagonists: Description of 52 Cases and Disproportionality Analysis in a Nationwide Pharmacovigilance Database

research Alopecia induced by tumour necrosis factor-alpha antagonists: description of 52 cases and disproportionality analysis in a nationwide pharmacovigilance database

26 citations , March 2014 in “Rheumatology”

Some drugs used to treat inflammation may cause hair loss.

research Scarless wound healing: Transitioning from fetal research to regenerative healing

79 citations , January 2018 in “Wiley Interdisciplinary Reviews-Developmental Biology”

Understanding how baby skin heals without scars could help develop treatments for adults to heal wounds without leaving scars.

research Case Series: Gene Expression Analysis in Canine Vogt-Koyanagi-Harada/Uveodermatologic Syndrome and Vitiligo Reveals Conserved Immunopathogenesis Pathways Between Dog and Human Autoimmune Pigmentary Disorders

20 citations , December 2020 in “Frontiers in Immunology”

The immune processes causing VKH and vitiligo are similar in dogs and humans.

research 1 The regulatory biology of the human pilosebaceous unit

17 citations , June 1997 in “Baillière's clinical obstetrics and gynaecology”

Scientists now better understand how human hair growth is controlled, including the roles of specific genes and proteins.

research In Vitro Evaluation of the Effect of a Not Cross-Linked Hyaluronic Acid Hydrogel on Human Keratinocytes for Mesotherapy

5 citations , February 2021 in “Gels”

HYDRO DELUXE BIO hyaluronic acid hydrogel is compatible with skin cells, may reduce inflammation, promote blood vessel growth, and protect against oxidative stress, suggesting it could help revitalize hair follicles.

research Evaluating Antiinflammatory and Antiandrogenic Effects of Garden Cress (Lepidium sativum L.) in HaCaT cells

5 citations , June 2018 in “Records of Natural Products”

Garden cress extract may help treat skin inflammation and androgen-related disorders.

research Accelerative action of topical piperonylic acid on mice full thickness wound by modulating inflammation and collagen deposition

3 citations , October 2021 in “PLoS ONE”

Piperonylic acid speeds up wound healing by reducing inflammation and boosting collagen.

Exosome Therapy from Hypoxia-Treated Mesenchymal Stem Cells Reduces TNF-α and Increases VEGF Levels in Fluconazole-Induced Alopecia Model

research Exosome Therapy from Hypoxia-treated Mesenchymal Stem Cells Reduces TNF-α and Increases VEGF Levels in Fluconazole-Induced Alopecia Model

November 2025 in “Molecular and Cellular Biomedical Sciences”

Exosome therapy from treated stem cells may help reduce inflammation and promote hair regrowth in alopecia.

research Referee report. For: Molecular mediators involved in skin healing: a narrative review [version 1; peer review: 1 approved with reservations]

January 2022 in “Faculty of 1000 Research Ltd”

Understanding molecular mediators can improve skin healing treatments.

research Keratin 17 modulates hair follicle cycling in a TNFα-dependent fashion

169 citations , May 2006 in “Genes & Development”

Keratin 17 is crucial for normal hair growth by regulating hair cycle transitions with TNFα.