research mTOR signaling in hair follicle and hair diseases: recent progress
The mTOR signaling pathway is crucial for hair health and targeting it may lead to new hair loss treatments.
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research Eclipta alba (Family: Asteraceae): A review of botanical, ethnopharmacological, phytochemical and pharmacological studies
Eclipta alba shows promise for medicinal use but needs more research.
research Systemic Antifungals
Terbinafine is the most effective medicine for fungal nail infections, especially for diabetics and those with weak immune systems.
research Finasteride in The Treatment of Female Androgenic Alopecia
Finasteride may help postmenopausal women with hair loss but is not effective for all and should be used cautiously in premenopausal women.
research Erasing the methyl mark: histone demethylases at the center of cellular differentiation and disease
Histone demethylases can change gene expression and may be linked to diseases like cancer.
research Proteomic analysis of human mesenchymal stromal cell secretomes: a systematic comparison of the angiogenic potential
Wharton's jelly secretomes are best for promoting blood vessel growth.
research Paneth Cells in Intestinal Homeostasis and Tissue Injury
Paneth cells help support stem cells and aid tissue regeneration after injury.
research Tissue regenerative delays and synthetic lethality in adult mice after combined deletion of Atr and Trp53
Removing both Atr and Trp53 genes in adult mice causes severe tissue damage and death due to DNA damage.
research Circadian clock-mediated control of stem cell division and differentiation: beyond night and day
The circadian clock is crucial for tissue renewal and regeneration, affecting stem cell functions and having implications for health and disease.
research Frontal fibrosing alopecia: reflections and hypotheses on aetiology and pathogenesis
FFA's causes may include environmental triggers and genetic factors.
research c-MYC-Induced Sebaceous Gland Differentiation Is Controlled by an Androgen Receptor/p53 Axis
The balance between androgen receptor and p53 is crucial for sebaceous gland differentiation.
research Wnt Signaling and Aging-Related Heart Disorders
Wnt signaling may be linked to heart diseases in aging and could be a target for future treatments.
research Control by a hair’s breadth: the role of microRNAs in the skin
MicroRNAs play a crucial role in skin and hair health, affecting everything from growth to aging, and could potentially be used in treating skin diseases.
research Epidermal Polarity Genes in Health and Disease
Disruptions in epidermal polarity genes can lead to skin diseases.
research Expression and function of nuclear receptor co-activator 4: evidence of a potential role independent of co-activator activity
NcoA4 may have roles beyond helping control gene activity, possibly affecting cell behavior and stability.
research Calcium regulation of stem cells
Calcium is important for stem cell function and maintenance, especially in blood and skin cells.
research Consensus on the use of oral isotretinoin in dermatology - Brazilian Society of Dermatology
The Brazilian Society of Dermatology agrees that oral isotretinoin is effective for acne and other skin conditions, and it's safe when monitored, but more research is needed on dosing and duration.
research Stem Cells behind the Barrier
Stem cell differentiation is crucial for skin barrier maintenance and its disruption can lead to skin diseases.
research Targeted therapy in melanoma
New treatments for advanced skin cancer are improving patient outcomes, but drug resistance and finding the right treatment combinations are still big challenges.
research A Pilot Study of a Grape Seed Procyanidin Extract for Lung Cancer Chemoprevention
Grape seed extract may safely and effectively help prevent lung cancer.
research Cytoskeletal Regulation of Dermal Regeneration
Targeting the actin cytoskeleton could improve skin healing and reduce scarring.
research Induction of hair follicle neogenesis with cultured mouse dermal papilla cells in de novo regenerated skin tissues
Scientists successfully grew new hair follicles in regenerated mouse skin using mouse and human cells.
research New small molecules in dermatology: for the autoimmunity, inflammation and beyond
New small molecule drugs show promise in treating complex skin diseases but need more safety research.
research The E6/E7 oncogenes of human papilloma virus and estradiol regulate hedgehog signaling activity in a murine model of cervical cancer
HPV genes and estradiol increase a cancer-related signaling pathway, which may be targeted for cervical cancer treatment.
research Transcriptomics analysis reveals molecular alterations underpinning spaceflight dermatology
Spaceflight can harm skin health by altering gene expression, affecting DNA, mitochondria, and skin barriers.
research Recent advances in drug repositioning and rediscovery for different therapeutic activities utilizing updated technological approaches
Using existing drugs for new treatments is cost-effective and safer.
research Skin in the Game: Stem Cells in Repair, Cancer, and Homeostasis
Elaine Fuchs' research shows how skin stem cells maintain health, aid in healing, and are involved in cancer.
research A symphony of signals: the intricate role of lncRNAs in dermatological disorders
lncRNAs are important for understanding and treating skin diseases.
research Androgenic Alopecia: Cross-Talk Between Cell Signal Transduction Pathways
Hair loss in Androgenetic alopecia (AGA) is due to altered cell sensitivity to hormones, not increased hormone levels. Hair growth periods shorten over time, causing hair to become thinner and shorter. This is linked to miscommunication between cell pathways in hair follicles. There's also a change in gene expression related to blood vessels and cell growth in balding hair follicles. The exact molecular causes of AGA are still unclear.
research Bioactive Substances Derived From Probiotic Lactobacillus acidophilus Reduce Motility And Viability In Cervical Cancer Cells
Lactobacillus acidophilus substances can kill and stop the spread of cervical cancer cells.