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Researchers found four key proteins that affect the development of a specific hair type in Yangtze River Delta white goats.

The main enzyme found in pubic skin that could be targeted to treat excessive hair growth is 5 alpha-R2.

Keratinocytes show more TGF-β system activity and collagen production as they age, which might affect wound scarring.

Key enzymes control androgen levels, affecting hormone activity and potential treatments.

The equine epididymis mainly uses type 1 5α-reductase, and both finasteride and dutasteride can inhibit its activity.

Fetal wound healing changes with development, affecting inflammation and collagen, which may influence scarring.

The study created a new method to test drugs that affect hormone processing in skin.

Type 3 5α-reductase is more common and finasteride and dutasteride strongly inhibit it.

Blocking the enzyme 11β-HSD1 might help treat obesity and metabolic issues.

17β-estradiol may help hair growth by increasing cannabinoid receptor type 1.

Keratin 17 is modified by RSK1 in response to growth and stress, affecting skin growth and stress response.

A new compound shows promise as a topical treatment for hair loss.

New steroidal compounds moderately block an enzyme related to testosterone conversion, less effectively than finasteride.

Inhibitors of 11β-HSD1 show potential for treating type 2 diabetes but require more testing for safety and effectiveness.

Selective non-steroidal inhibitors of 5α-reductase type 1 can help treat DHT-related disorders.

Exercise improves insulin sensitivity and hormone regulation in PCOS rats.

Avicequinone C, a compound found in the Avicennia marina plant, can reduce hair loss by inhibiting a hormone linked to androgenic alopecia.

The gene SDR5A1 is found in scalp hair of both hirsute and normal individuals, but it does not explain differences in hair growth.

Blocking 11β-HSD1 can lessen the harmful effects of glucocorticoids on hair growth cells.

PDGF isoforms can promote and sustain hair growth.

A genetic mutation in the hHa1 gene creates a smaller, but still functional, hair protein without causing hair problems.

Scientists discovered two versions of a new human hair keratin gene.

Vitamin D boosts a specific gene activity in kidney cells that could improve heart and kidney function.

Increased 11β-HSD1 activity in skin may contribute to aging and could be targeted to reduce aging effects.

Targeting glucocorticoid action might help treat type-2 diabetes, but human trials are needed.

Patients with myotonic dystrophy often have skin problems that suggest early aging and vitamin D issues, and the severity of these problems is linked to their genetic condition and vitamin D levels.

Cepharanthine may help treat Equid herpesvirus type 8 by reducing oxidative stress.

Psoriasis involves an imbalance between certain immune cells, and targeting these could help restore skin health.

Finasteride poorly inhibits type 1 5AR, affecting its effectiveness.

Saw palmetto extract can block the enzyme that converts testosterone in pig prostate cells.