research Functional Interpretation of Genome-Wide Association Study Evidence in Alopecia Areata
Alopecia areata is linked to immune-related genes, suggesting JAK inhibitors as a potential treatment.
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840-870 / 1000+ results research Effect of Hyaluronic Acid and Poly-L-Lactic Acid Dermal Fillers on Collagen Synthesis: An in vitro and in vivo Study
Hyaluronic acid increases collagen synthesis safely, while poly-L-lactic acid may cause complications by affecting fibroblasts.
research TSPO activation modulates the effects of high pressure in a rat ex vivo glaucoma model
Activating TSPO helps protect the retina from damage caused by high eye pressure in glaucoma.
research An important role of podoplanin in hair follicle growth
Deleting podoplanin in mice promotes hair growth by enhancing cell migration.
research Involvement of mechanical stress in androgenetic alopecia
Mechanical stress contributes to hair loss in androgenetic alopecia.
research 17-Oximino-5-androsten-3β-yl esters: synthesis, antiproliferative activity, acute toxicity, and effect on serum androgen level
Some synthesized compounds were more effective than Finasteride in reducing prostate cancer cell growth and androgen levels.
research Follicular Hybrid Cyst With Isthmic-Catagen, Pilomatrical, and Syringocystadenoma Papilliferum Components
A rare neck cyst in a 47-year-old man showed diverse skin cell types and was not linked to HPV.
research Carcinogenesis of the Human Scalp. An Immunometabolic Centered View
Hair protects the scalp from skin cancer by aiding immune defense.
research Giant Morpheaform Basal Cell Carcinoma Mimicking Scarring Alopecia: Exception Prone to Neglect
A rare type of skin cancer on the scalp can be mistaken for hair loss, causing delayed diagnosis and severe damage.
research miR-29a-5p Inhibits Prenatal Hair Placode Formation Through Targeting EDAR by ceRNA Regulatory Network
miR-29a-5p prevents the formation of early hair structures by targeting a gene important for hair growth and is regulated by a complex network involving lncRNA627.1.
research Roles of the Hedgehog Signaling Pathway in Cutaneous Physiology and Oncology
The Hedgehog Signaling Pathway is important for skin and hair development and skin cancer treatment, but more research is needed to understand it fully.
research Polycystic Ovarian Syndrome: Long-Term Health Consequences
Women with PCOS have a higher risk of diabetes, heart problems, certain cancers, and mental health issues, but early treatment can help manage these risks.
research Summary of the Preceding Three Alopecia Areata Research Summits: What’s Past Is Prologue
New treatments and strategies are needed for Alopecia Areata, focusing on immune response and better trial designs.
research Alopecia areata: What’s new in epidemiology, pathogenesis, diagnosis, and therapeutic options?
New insights into the causes and treatments for the autoimmune hair loss condition Alopecia areata have been made.
research CAQ Corner: Basic concepts of transplant immunology
The document explains how the immune system reacts to organ transplants and the treatments used to prevent rejection.
research Epidermal Notch1 recruits innate lymphoid cells to orchestrate normal skin repair
Notch1 helps skin heal by attracting cells that aid repair.
research Activating an adaptive immune response from a hydrogel scaffold imparts regenerative wound healing
Hydrogel scaffolds can help wounds heal better and grow hair.
research Mesenchymal Stem Cells from Adipose Tissue in Clinical Applications for Dermatological Indications and Skin Aging
Fat-derived stem cells show promise for skin repair and reducing aging signs but need more research for consistent results.
research The role of the microbiome in scalp hair follicle biology and disease
The scalp's microorganisms significantly affect hair health and disease.
research Role of janus kinase inhibitors in the treatment of alopecia areata
Janus kinase inhibitors show promise in treating alopecia areata but need better topical formulations.
research Runx3 is involved in hair shape determination
Runx3 helps determine hair shape.
research Physiopathological role of the enzymatic complex 5α-reductase and 3α/β-hydroxysteroid oxidoreductase in the generation of progesterone and testosterone neuroactive metabolites
The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.
research Hair follicle-derived melanocyte transplant as a promising treatment strategy for vitiligo
Hair follicle-derived melanocyte transplant could effectively treat vitiligo by restoring skin color.
research Identification of immune microenvironment changes, immune-related pathways and genes in male androgenetic alopecia
The research suggests immune system changes and specific gene expression may contribute to male hair loss, proposing potential new treatments.
research Regenerative Medicine of Epidermal Structures
New treatments for skin and hair repair show promise, but further improvements are needed.
research Melanogenesis is coupled to murine anagen: Toward new concepts for the role of melanocytes and the regulation of melanogenesis in hair growth
Hair color production in mice is closely linked to the hair growth phase and may also influence hair growth itself.
research The cell-surface marker MTS24 identifies a novel population of follicular keratinocytes with characteristics of progenitor cells
MTS24 marks a new type of skin cell that helps hair growth and repair.
research Hairless and Wnt Signaling: Allies in Epithelial Stem Cell Differentiation
The HR protein's role as a repressor is essential for controlling hair growth.
research Activator Protein-1 Activity Regulates Epithelial Tumor Cell Identity
AP-1 controls tumor cell type by affecting key signaling pathways.
research Alopecia areata and risk of atopic and autoimmune conditions: population-based cohort study
People with alopecia areata are more likely to have other immune-related conditions.