research The Hair Follicle: A Paradoxical Androgen Target Organ
Androgens can both promote and prevent hair growth due to differences in gene expression in hair follicles.
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research Human androgenic steroids affect growth of dermatophytes in vitro
Androgenic steroids can slow down or stop the growth of certain skin fungi.
research Alopecia androgénica femenina: nuevos factores fisiopatológicos y futuras tendencias para un abordaje clínico más integral
New factors in female hair loss include genetics, hormones, stress, and inflammation; future treatments should also focus on these areas and consider the patient's emotional well-being.
research Realising the therapeutic potential of neuroactive steroid modulators of the GABAA receptor
Neuroactive steroids show promise for treating mental and neurological disorders by targeting GABA_A receptors.
research Novel progestogenic androgens for male contraception: design, synthesis, and activity of C7 α-substituted testosterone
New testosterone analogs show promise for male contraception with better activity and potentially fewer side effects.
research A decade of progress in androgenetic alopecia management: Emerging therapies and multimodal strategies
Androgenetic alopecia treatments are becoming more personalized and include new therapies like topical antiandrogens and regenerative strategies.
research Common Causes of Hair Loss and Their Treatment Options
Various treatments exist for hair loss, but no definitive solution.
research ACNE
Acne significantly affects mental health and quality of life, with research suggesting hormonal and genetic factors in its development and emphasizing early treatment to prevent scarring.
research Pilosebaceous Unit (PSU)
Androgens and other hormones affect hair growth and skin conditions like acne.
research Frontal Fibrosing Alopecia
Frontal Fibrosing Alopecia is a type of hair loss affecting mostly older women, with no agreed best treatment.
research Baiting Proteins with C60
C60 fullerenes can alter protein function and may help develop new disease inhibitors.
research Low Molecular Weight Collagen Peptide (LMWCP) Promotes Hair Growth by Activating the Wnt/GSK-3β/β-Catenin Signaling Pathway
A type of collagen helps hair grow by boosting cell growth and activating a specific hair growth pathway.
research SRD5A3 Is Required for Converting Polyprenol to Dolichol and Is Mutated in a Congenital Glycosylation Disorder
Mutations in the SRD5A3 gene cause a new type of glycosylation disorder by blocking the production of a molecule necessary for protein glycosylation.
research Finasteride and sexual side effects
Finasteride may cause sexual side effects like erectile dysfunction, but they are reversible and affect less than 2% of men.
research Endocrine and Reproductive Effects of Polycystic Ovarian Syndrome
Losing 5-10% body weight can improve PCOS symptoms, letrozole is better than clomiphene for fertility, and managing weight and blood sugar is important to reduce pregnancy complications.
research Androgenic and anti-androgenic effects of progesterone derivatives with different halogens as substituents at the C-6 position
Different halogens on progesterone derivatives can either block or mimic male hormone effects, depending on their type and amount.
research Oral isotretinoin combined with topical clobetasol 0.05% and tacrolimus 0.1% for the treatment of frontal fibrosing alopecia: a randomized controlled trial
Taking oral isotretinoin with creams worked better for treating a type of hair loss than creams alone.
research Alopecia and its medical management
Hair loss can be treated with medications like minoxidil and finasteride or surgery, but treatment effectiveness varies by alopecia type and accurate diagnosis is important.
research Hétérogénéité tumorale du cancer de la prostate et infection par le SARS-CoV2 : une relation complexe impliquant les vésicules extracellulaires et le récepteur des androgènes
Extracellular vesicles and androgen receptors may help identify prostate cancer resistance and reduce SARS-CoV-2 infection.
research Cicatricial pattern hair loss is not a variant of lichen planopilaris
Cicatricial pattern hair loss is likely advanced common baldness, not a type of lichen planopilaris.
research Adolescent hair loss
Hair loss in teenagers is hard to treat and lacks a cure, with some treatments available depending on the type of hair loss.
research Clinical Case Notes. Castleman's disease of the lacrimal gland
The document discusses various eye conditions and their treatments, including a rare eye cancer in a baby, vision loss from a cancer drug, cataracts from a baldness treatment, a rare skin disorder, and a specific type of eye disease diagnosed with a special imaging technique.
research Onion and leek consumption, garlic supplement use and the incidence of cancer
Eating onions and garlic may have health benefits, but effects vary by type and preparation.
research 706 Influence of socioeconomic factors on the presence and intensity of erectile dysfunction in men with coronary artery disease
Men with lower education levels are more likely to have erectile dysfunction if they have coronary artery disease.
research Assessing dutasteride-associated sexual dysfunction using the U.S. Food and Drug Administration Adverse Event Reporting System
Dutasteride is linked to a higher chance of sexual dysfunction, especially in younger males and the elderly.
research Mitochondrial dysfunction in an animal model of diabetic neuropathy is associated with a reduction of neurosteroid synthesis.
Diabetic neuropathy in mice is linked to poor mitochondria function and lower brain hormone production.
research Fractional non-ablative laser-assisted drug delivery leads to improvement in male and female pattern hair loss
Laser-assisted drug delivery improves hair loss.
research Effect of finasteride particle size reduction on its pharmacokinetic, tissue distribution and cellular permeation.
Smaller finasteride particles increase effectiveness in treating hair loss.
research The genetics of androgenetic alopecia
Genes and hormones cause hair loss, with four genes contributing equally.
research In vitro selective inhibition of human UDP-glucuronosyltransferase (UGT) 1A4 by finasteride, and prediction of in vivo drug–drug interactions
Finasteride affects UGT1A4 enzyme, but not enough to cause issues when combined with other drugs.