4025 citations
,
December 2003 in “Human Reproduction” The 2003 consensus updated PCOS diagnosis criteria and linked PCOS to higher risks of diabetes and heart problems, recommending lifestyle changes to lower these risks.
50 citations
,
July 2000 in “Dermatologic Surgery” Female and male AGA are different diseases.
31 citations
,
March 2017 in “Journal of The American Academy of Dermatology” Some breast cancer patients developed permanent hair loss after chemotherapy and hormonal therapy, showing patterns similar to common baldness and alopecia areata.
30 citations
,
September 2017 in “Clinics in Dermatology” Men with common hair loss may have a higher risk of heart disease and diabetes, and should be checked for these conditions.
23 citations
,
May 2020 in “Cell Death and Disease” Blocking the FGF5 gene in sheep leads to more fine wool and active hair follicles due to changes in certain cell signaling pathways.
3 citations
,
February 2019 in “Journal of Cosmetic Dermatology” The effects of estrogen on human scalp hair growth are unclear and need more research.
3 citations
,
September 2016 in “Natural Product Communications” Germacrene analogs, especially 8-Hydroxy germacrene B, are more effective than germacrone at blocking a hormone-related enzyme and could help treat hair loss.
1 citations
,
January 1998 in “Seminars in Plastic Surgery” Hair transplantation using micro- and minigraft megasessions is safe, effective, and provides natural results with high patient satisfaction.
Early-onset baldness is linked to genetics, lifestyle, and can indicate higher risk for heart and metabolic diseases, and affects mental health.
December 2022 in “Research Square (Research Square)” Key genes linked to immune response are upregulated in hair follicles and skin tissues in chronic discoid lupus erythematosus.
October 2022 in “Research Square (Research Square)” Key genes linked to immune response are highly active in lupus-affected hair follicles.
4809 citations
,
January 2004 in “Fertility and Sterility” The 2003 consensus updated PCOS diagnosis criteria and highlighted increased risks of diabetes and heart disease for those affected.
304 citations
,
July 2006 in “Journal of The American Academy of Dermatology” Videodermoscopy improves diagnosis of hair and scalp disorders and may reduce scalp biopsies.
237 citations
,
December 2001 in “Urology” Blocking the enzyme 5α-reductase can shrink the prostate and help treat enlarged prostate issues.
204 citations
,
February 2000 in “Current Medicinal Chemistry” Antiandrogens like flutamide are effective in treating conditions like prostate cancer and hair loss, but there's a need for more potent versions. Understanding their structure can help develop better treatments.
196 citations
,
May 2001 in “The journal of investigative dermatology/Journal of investigative dermatology” Sebocytes play a key role in controlling androgen levels in human skin.
192 citations
,
March 1998 in “British Journal of Dermatology” Minoxidil boosts growth factor in hair cells, potentially promoting hair growth.
155 citations
,
December 2003 in “British Journal of Dermatology” Hair loss increases with age; alcohol raises risk, more female partners lowers it.
152 citations
,
December 2007 in “Gender Medicine” Male and female skin differ due to hormones, affecting conditions like hair loss, acne, and skin cancer, and suggesting a need for gender-specific treatments.
137 citations
,
January 2000 in “Skin Pharmacology and Physiology” The document recommends using both clinical evaluation and various measurement methods to assess skin greasiness, considering factors like temperature and hormones.
129 citations
,
October 2000 in “British Journal of Dermatology” Finasteride helps increase hair growth in men with hair loss.
110 citations
,
July 2010 in “Journal of The American Academy of Dermatology” Hair loss linked to higher heart disease risk in both men and women.
102 citations
,
January 2003 in “Dermatology” Smoking may contribute to hair loss in men.
87 citations
,
May 2012 in “PLOS Genetics” Six new genetic regions linked to early hair loss also connect to Parkinson's disease and prostate cancer, possibly leading to new treatments.
85 citations
,
June 2006 in “Best Practice & Research Clinical Endocrinology & Metabolism” The document concludes that hirsutism is the main sign for diagnosing hyperandrogenism, which requires a detailed patient history and physical exam.
77 citations
,
April 2009 in “British Journal of Dermatology” Aromatase gene variation may increase female hair loss risk.
69 citations
,
November 2010 in “Middle East Fertility Society Journal” PCOS affects women's health by increasing the risk of diabetes, heart disease, and reproductive issues.
69 citations
,
April 2010 in “British Journal of Dermatology” Balding men, especially young ones, may have higher risk of heart issues and diabetes; check cholesterol levels.
60 citations
,
September 2001 in “Journal of the American Academy of Dermatology” Insulin resistance contributes to hormone imbalances in many women with polycystic ovary syndrome.
49 citations
,
January 2004 in “Dermatology” Men with a family history of hair loss are more likely to experience it themselves, especially if both parents have hair loss.