152 citations
,
January 2004 in “Current anthropology” Humans lost body hair relatively recently in evolution.
129 citations
,
October 2007 in “The New England Journal of Medicine” Over one-third of women experience hair loss, with female-pattern hair loss being most common, and treatments include minoxidil and possibly hair transplantation.
114 citations
,
January 2007 in “Drug Safety” Some drugs can cause skin, nail, and hair problems, which are important for healthcare professionals to recognize and report.
87 citations
,
April 2018 in “Biochemical and Biophysical Research Communications” Exosomes from dermal papilla cells can help grow hair and might treat hair loss.
83 citations
,
December 2001 in “Journal of Investigative Dermatology” Minoxidil boosts hair growth by targeting adenosine and possibly sulfonylurea receptor 2B.
81 citations
,
August 2014 in “Lasers in Surgery and Medicine” Red light therapy is safe and effectively increases hair growth in women with hair loss.
75 citations
,
October 2016 in “Genes & Development” Cells in hair follicles help create fat cells in the skin by releasing a protein called Sonic Hedgehog.
66 citations
,
June 2010 in “Experimental Dermatology” The hair follicle is a great model for research to improve hair growth treatments.
66 citations
,
June 2006 in “Journal of The American Academy of Dermatology” Finasteride increases hair weight and count in men with hair loss, with best results after four years.
59 citations
,
May 2014 in “Expert Opinion on Therapeutic Targets” The document concludes that targeting 5α-reductase, the androgen receptor, and hair growth genes, along with using compounds with anti-androgenic properties, could lead to more effective hair loss treatments.
53 citations
,
August 2019 in “Journal of The American Academy of Dermatology” Oral minoxidil and topical minoxidil 5% both effectively improve female-pattern hair loss with safe side effects.
50 citations
,
December 2011 in “Skin Research and Technology” The algorithm effectively removes hair from skin images, improving melanoma diagnosis accuracy.
49 citations
,
February 2019 in “The Journal of Clinical Endocrinology and Metabolism” Use "female pattern hair loss" term, assess androgen excess, treat with minoxidil and other medications if needed.
46 citations
,
March 2015 in “Regeneration” Mice can grow new hair follicles after skin wounds through a process not involving existing hair stem cells, but requiring more research to understand fully.
45 citations
,
September 1998 in “Journal of Investigative Dermatology” The enzyme 17β-HSD type 2 mainly performs oxidation in human sebaceous glands, which may help protect against acne.
44 citations
,
January 2013 in “International Journal of Trichology” Finasteride 5 mg/day effectively treats hair loss in postmenopausal women without hyper-androgenism.
43 citations
,
October 2003 in “Journal of The American Academy of Dermatology” Hair transplanting is a useful, often overlooked treatment for female pattern hair loss.
40 citations
,
October 2012 in “British Journal of Dermatology” Minoxidil helps regrow hair in female pattern hair loss, but more research needed for other treatments.
39 citations
,
October 1967 in “British Journal of Dermatology” Hair loss in women often doesn't follow a pattern, isn't linked to age, may be genetic, and can be related to thyroid issues or other health factors.
38 citations
,
October 2011 in “Analytical biochemistry” Hair proteins have weak spots in their α-helical segments.
35 citations
,
May 2012 in “Cochrane Database of Systematic Reviews” Minoxidil effectively treats female pattern hair loss.
35 citations
,
January 2000 in “Dermatology” Hair loss common in Norwegian men, affecting self-esteem and life quality.
33 citations
,
August 2013 in “British Journal of Dermatology” Lack of small, fine hair on the front hairline is a key sign of frontal fibrosing alopecia.
32 citations
,
March 2020 in “Drug Design Development and Therapy” Finasteride shows promise for female hair loss, but more research needed.
31 citations
,
May 2008 in “Drug Discovery Today: Disease Mechanisms” Different hair growth problems are caused by genetic issues or changes in hair growth cycles, and new treatments are being developed.
25 citations
,
September 2018 in “Scientific Reports” Morroniside may help hair grow and stay in its growth phase by affecting certain cell signals.
25 citations
,
August 2015 in “Journal of cosmetic dermatology” African American women report more hair issues and use different hair care practices than Caucasian women, and have different hair and scalp characteristics.
25 citations
,
February 2014 in “British journal of dermatology/British journal of dermatology, Supplement” Intralesional triamcinolone acetonide can regrow hair in alopecia areata but often has temporary effects and side effects.
25 citations
,
January 2009 in “Oral and Maxillofacial Surgery Clinics of North America” Successful hair transplant surgery depends on careful patient selection, proper surgical plan and technique, and attentive aftercare.
24 citations
,
January 2006 in “Skin Pharmacology and Physiology” Finasteride reverses early hair loss and promotes growth.