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Type I Keratin 17 Protein Is Phosphorylated on Serine 44 by p90 Ribosomal Protein S6 Kinase 1 in a Growth- and Stress-Dependent Fashion

research Type I Keratin 17 Protein Is Phosphorylated on Serine 44 by p90 Ribosomal Protein S6 Kinase 1 (RSK1) in a Growth- and Stress-dependent Fashion

30 citations , December 2011 in “Journal of biological chemistry/The Journal of biological chemistry”

Keratin 17 is modified by RSK1 in response to growth and stress, affecting skin growth and stress response.

research Incidence of type 2 diabetes mellitus in men receiving steroid 5α-reductase inhibitors: population based cohort study

29 citations , April 2019 in “BMJ. British medical journal”

Men taking dutasteride or finasteride have a slightly higher risk of developing type 2 diabetes.

Polycystic Ovary Syndrome in Adolescence and Type 2 Diabetes

research PCOS in Adolescence and Type 2 Diabetes

28 citations , November 2014 in “Current Diabetes Reports”

Girls with PCOS during adolescence have a higher risk of developing type 2 diabetes, and early treatment can help manage this risk.

research Intermittent and Persistent Type 2 lupus: patient perspectives on two distinct patterns of Type 2 SLE symptoms

14 citations , August 2022 in “Lupus Science & Medicine”

SLE patients experience two patterns of non-inflammatory symptoms: intermittent and persistent.

research Hair follicle characteristics as early marker of Type 2 Diabetes

13 citations , August 2016 in “Medical Hypotheses”

Hair characteristics might be early signs of Type 2 Diabetes and could help with early prevention.

Effect of MK-386, a Novel Inhibitor of Type 1 5 Alpha-Reductase, Alone and in Combination with Finasteride, on Serum Dihydrotestosterone Concentrations in Men

research Effect of MK-386, a novel inhibitor of type 1 5 alpha-reductase, alone and in combination with finasteride, on serum dihydrotestosterone concentrations in men.

6 citations , August 1996 in “The Journal of Clinical Endocrinology and Metabolism”

MK-386 and finasteride together effectively reduce DHT levels, potentially treating acne and male pattern baldness.

research A mutation in the type II hair keratin KRT86 gene in a Han family with monilethrix

3 citations , February 2011 in “Journal of Biomedical Research/Journal of biomedical research”

A new mutation in the KRT86 gene was found to cause the hair disorder monilethrix in a Han family.

Characterization of Myotonic Dystrophy Type I Cell Models and Drug Evaluation by a Cell-Based Quantification Platform

research Characterisation of Myotonic Dystrophy type I cell models and drug evaluation by a cell- based quantification platform.

November 2024 in “Communities in ADDI (University of the Basque Country)”

Antisense oligonucleotides show promise for treating Myotonic Dystrophy type I.

research Type-2 immunity associated with type-1 related skin inflammatory diseases: friend or foe?

May 2024 in “Frontiers in Immunology”

Type-2 immunity may influence skin diseases and could be targeted for treatment.

research The Princeton III Consensus Recommendations for the Management of Erectile Dysfunction and Cardiovascular Disease

January 2013 in “Yearbook of Urology”

The Princeton III Consensus recommends assessing cardiovascular risk in men with erectile dysfunction and prioritizing heart health before treating ED, especially in those with potential heart disease.

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