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A substance called Compound 2g can strongly block STS (a hormone-related enzyme) without affecting estrogen levels, making it potentially good for treating breast cancer.

The structure of SRD5A reveals how it reduces steroids, aiding drug design for related health conditions.

The method accurately measures certain steroids in human hair, showing different levels in males and females.

Steroid-binding globulins have important roles beyond just transporting steroids.

A new method accurately measures long-term steroid levels in human hair.

Patients need better information about the risks of long-term steroid use.

Researchers created a new method to measure brain steroids, finding higher levels of certain steroids and changes due to a drug.

Prednisolone can quickly regrow hair in alopecia universalis, but hair falls out after stopping it.

CB-03-04 shows promise as a treatment for prostate issues due to its strong anti-androgen effects.

Heart-specific steroid metabolism is crucial in cardiac hypertrophy.

Plant steroid hormones show growth, health, and medicinal benefits in various organisms, including potential for treating diseases.

This enzyme helps metabolize fatty acids and isoleucine, and could be key in treating neurological diseases and certain cancers.

Scientists found new, better-working inhibitors for a hormone-related enzyme.

CYP11A1 is crucial for skin health and disease by producing important steroids.

Ketoconazole improved symptoms of ACTH-independent Cushing syndrome despite inconclusive initial scans.

LY320236 is a strong blocker of two enzymes that change testosterone into dihydrotestosterone and might help treat conditions related to male hormones.

New genes and pathways are important for testosterone production and male sexual development.

A young woman's symptoms suggested PCOS, but tests and surgery confirmed and treated a rare ovarian tumor, resolving her condition.

Serum steroid profiling, especially 11-deoxycortisol, helps distinguish between adrenocortical carcinoma and adenoma, considering sex and functional status.

A new compound that could treat various androgen-related conditions was created and analyzed.

Drospirenone can hide symptoms of certain hormonal disorders, complicating diagnosis.

Key enzymes control androgen levels, affecting hormone activity and potential treatments.

Trienones are more effective at inhibiting the enzyme linked to hair loss than dienones.

CAH requires a multidisciplinary approach, and while current treatments help, future therapies show promise.

The more lipophilic the progesterone derivative, the better it binds to androgen receptors and has antiandrogenic effects.

High levels of 3 alpha-diol glucuronide in the blood are a marker of increased androgen action in women with excessive hair growth of unknown cause.

Some newly made compounds are promising for treating enlarged prostate, hair loss, viruses, and prostate cancer, and might be better than current drugs.

Prostate cancer cells can make their own androgens to activate the androgen receptor, and treatments like abiraterone may increase this ability, suggesting new therapies should target the entire steroid-making pathway.

Compounds 15, 20, and 25 are strong inhibitors of human steroid 5α-reductase type 2.