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The document concludes that careful planning and execution of facial gender affirmation surgery after at least 12 months of hormonal therapy can improve the quality of life for transgender individuals.

Keloids on the penis are rare, often triggered by circumcision, and rarely recur after surgery.

A postmenopausal woman's virilization was caused by a rare ovarian tumor that was hard to detect but was successfully treated with surgery.

Some antiandrogens may lower testosterone better than others, but it's unclear which is best for feminization in transgender women; more research is needed.

An ovarian tumor caused a woman's male-like symptoms, which improved after surgery.

A woman's masculine symptoms were caused by an ovarian tumor, which improved after surgery.

The statement offers guidance for hormone therapy and surgery to help gender-incongruent adults affirm a male identity.

The conclusion is that recognizing the difference between gender identity and biological sex is crucial in dermatology to improve patient care and research accuracy.

A new genetic mutation causes severe Leydig cell hypoplasia, affecting sexual development.

A woman had both Graham Little-Piccardi-Lassueur syndrome, causing hair loss, and complete androgen insensitivity syndrome, making her genetically male but physically female. This suggests androgens don't affect the hair loss condition.

Polycystic Ovary Syndrome (PCOS) affects Iranian women's feelings of femininity and self-image.

Early physical exams are crucial for timely Klinefelter syndrome diagnosis.

The same gene mutation can cause different symptoms in family members.

Proper planning and technique in upper-face feminization surgery are crucial to avoid complications and revisions.

Male hypogonadism affects skin and hair, causing thin skin, less hair, and skin reactions to treatment.

Excessive male hormones in women cause symptoms like unwanted hair growth, and treatment requires careful medical evaluation.

DSDs are birth conditions causing unusual sex development, managed with personalized care and sometimes surgery, but still lack a standard treatment approach.

A 17-year-old female with adrenogenital syndrome produces very high levels of androgens, which prevent complete feminization despite high estrogen doses.

The safety and effectiveness of gender-affirming treatments for children are uncertain, with potential long-term risks like infertility.

Mutations in the androgen receptor gene cause androgen insensitivity, leading to female traits in genetically male individuals.

The document recommends a multidisciplinary approach and experience sharing to advance facial feminization surgery as a medical field.

Early diagnosis and treatment are crucial for complex medical conditions.

Testosterone treatment effectively causes male physical development in transgender male adolescents but may lead to side effects like acne, higher BMI and blood pressure, lower good cholesterol, and decreased bone density.

Adolescents and young adults with Prader-Willi syndrome show a range of sexual interests and behaviors.

Transgender individuals face unique skin issues, often due to hormone therapy, requiring specialized and stigma-free dermatologic care.

Men are increasingly interested in cosmetic treatments that enhance masculinity and address aging without downtime, with tailored approaches for different ethnicities and a focus on hair restoration and body contouring.

Ovarian hyperthecosis caused high testosterone and virilization symptoms in a 60-year-old woman, which improved after surgery.

Blocking a specific enzyme in male rat fetuses leads to the development of nipples and feminized genitalia.

A rare ovarian tumor caused a postmenopausal woman to develop male-like features, which improved after surgery.