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Obese women with PCOS show a male-like pattern in certain fat tissue gene expressions.

Some ovarian tumors can cause masculinization, and it's important to check for various causes when this symptom is present.

Facial feminization surgery is safe and patients are satisfied, but more detailed research is needed.

Men with hormonal imbalances similar to PCOS may have increased risk of metabolic and heart diseases.

Gender-affirming hormone therapy and surgery affect gut bacteria differently.

The document concludes that personalized hormonal treatments are important for transgender individuals and more research is needed for non-binary treatments.

A 71-year-old woman developed male-like features due to high testosterone levels caused by a benign ovarian tumor, which was successfully removed by surgery.

A specific metabolite, not a receptor protein, triggers the production of certain kidney enzymes, but this process is disrupted in mice with a mutation causing testicular feminization.

Late diagnosis of congenital adrenal hyperplasia can greatly affect physical development, gender identity, and sexual health.

Testosterone makes XX skin more like male skin by changing its structure and cell makeup.

Men might have a version of the female disease, polycystic ovarian syndrome, shown by changes in hormone levels and early baldness, but more research is needed to fully understand it.

New methods help diagnose skin conditions caused by too much male hormone in women, like acne, hair loss, and excess hair growth.

A man with Klinefelter syndrome had a leg ulcer that didn't heal well, even with treatment.

A woman's mature cystic teratoma caused her virilization by producing testosterone.

Creating evidence-based guidelines for gender incongruence is difficult due to the personalized nature of transgender medicine.

Transgender patients on hormone therapy experience more acne and hair loss, but less skin inflammation.

Orthognathic surgeons play a key role in modifying masculine facial features to be more feminine, often improving transgender women's quality of life.

Masculinizing hormone therapy increases the risk of hair loss in transgender and gender-diverse patients.

Genetic defects in androgen production are linked to male developmental disorders and are improving treatment understanding.

A woman's virilization symptoms were caused by her partner's use of testosterone cream, which resolved after they separated.

Testosterone therapy for transmasculine individuals is generally safe with medical supervision, improves mental health, and has mixed effects on physical health.

A postmenopausal woman's masculine symptoms improved after surgery for a hormone-producing ovarian tumor.

A woman's severe hirsutism was caused by Leydig cell tumors in her ovaries, which improved after surgery.

Hirsutism is abnormal male-pattern hair growth in females due to excess androgens.

Facial feminization surgery helps make facial features more feminine, improving patient satisfaction and safety.

Masculine facial features may not reliably indicate heritable health, and more research is needed.

Medicalizing male and female bodies can have negative impacts.