research Proteomic tools for the investigation of human hair structural proteins and evidence of weakness sites on hair keratin coil segments
Hair proteins have weak spots in their α-helical segments.
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480-510 / 1000+ results research Evidence for Genetic Heterogeneity in Monilethrix
research QUESTIONS OF TEACHING MEDICAL BIOCHEMISTRY AS PART OF AN INTEGRATED EDUCATIONAL PROGRAM IN A MEDICAL UNIVERSITY
Integrating medical biochemistry with other subjects improves clinical problem-solving skills.
research Bioequivalence Study of Finasteride Tablets in Human Plasma by HPLC-MS
The test and reference finasteride tablets are bioequivalent.
research Monoclonal Antibody Against Prolactin Receptor: A Randomized Placebo-Controlled Study Evaluating Safety, Tolerability, and Pharmacokinetics of Repeated Subcutaneous Administrations in Postmenopausal Women
The drug BAY 1158061 is safe, well-tolerated, and shows potential for treating diseases related to prolactin.
research P08 Developing a rapid ATP assay to understand skin and hair follicle microbiome and assess skin microbiome dysbiosis
The ATP assay can measure skin microbiome changes and recovery, with ethanol-treated skin taking longer to recover than tape-stripped skin.
research A validated RP-HPLC method to investigate finasteride in human skin after in vitro topically applying vesicular nanocarrier.
The method accurately measures finasteride in skin after using special carriers.
research Farmácia Normal - Vila do Conde e nos Serviços Farmacêuticos do Opca Bolnica Pula - Pula, Croácia
research The validation of estradiol extraction and analysis from hair
Hair can reliably measure average estradiol levels over months in humans and monkeys.
research Characterization of spironolactone and metabolites derivatized using Girard's reagent P using mass spectrometry and ion mobility spectrometry
Girard's reagent P improves detection of spironolactone and its metabolites.
research Determination of Finasteride in Human Plasma by LC/MS/MS and Study on Its Pharmacokinetics
The method accurately measures finasteride in plasma and is suitable for clinical use.
research Luminescence and other photoprocesses in hair follicles in the disorder Trichostasis spinulosa
research Elemental hair analysis: A review of procedures and applications
Hair elemental analysis could be useful for health and exposure assessment but requires more standardization and research.
research Precision Dermatology: A Review of Molecular Biomarkers and Personalized Therapies
Personalized medicine in dermatology uses molecular biomarkers to improve diagnosis and treatment but needs further advancements for practical use.
research A guide to the use of bioassays in exploration of natural resources
Bioassays help find useful compounds in nature for making medicines, supplements, and cosmetics.
research Enhanced ex vivo skin retention of bicalutamide using a nano-in-micro composite: Drug-loaded lipid vesicles in a dissolving microarray patch
The new drug delivery system improves bicalutamide skin retention for better treatment of hair loss.
research Spectrophotometric determination and estimation of minoxidil in tablet dosage form by UV
Researchers developed a simple and accurate method to measure Minoxidil in tablets using UV light.
research Real-World Outcomes and Healthcare Utilization of Lanadelumab in Spain: Insights from First Cohort of Difficult-to-Treat Hereditary Angioedema Cases
Lanadelumab greatly reduces hospital visits and angioedema episodes, improving life quality for hereditary angioedema patients.
research Non-invasive human skin transcriptome analysis using mRNA in skin surface lipids
A new non-invasive method can analyze skin mRNA to understand skin diseases better.
research FLCN, a novel autophagy component, interacts with GABARAP and is regulated by ULK1 phosphorylation
The protein FLCN is involved in cellular cleanup and is regulated by ULK1.
research Monitoring spatially resolved trace elements in polar bear hair using single spot laser ablation ICP-MS
Laser ablation ICP-MS is effective for tracking trace elements in polar bear hair over time.
research A systematic method for the sensitive and specific determination of hair lipids in combination with chromatography
A new method accurately measures hair lipids, revealing individual differences.
research Finasteride Quantification in Human Plasma by High-Performance Liquid Chromatography Coupled to Electrospray Ionization Tandem Mass Spectrometry. Application to a Comparative Pharmacokinetics Study
New method measures finasteride in plasma, finds two formulations bioequivalent.
research Program and Abstract of 16th APALMS 2018
Laser technologies improve medical treatments and outcomes.
research Uncertainty for HPLC Assay of Finasteride and Content Uniformity in Its Tablets
The method for measuring uncertainty in finasteride tablets is reliable.
research A Single-Arm, Open-Label, Phase Ib Clinical Study Evaluating the Efficacy and Safety of Durvalumab in Combination with Albumin-Bound Paclitaxel and Carboplatin as Neoadjuvant Therapy for Resectable Stage III Non-Small Cell Lung Cancer
The treatment showed high response rates and was well-tolerated, potentially extending patient survival.
research UPLC-MS/MS method for the simultaneous quantification of caffeine and illicit psychoactive drugs in hair using a single-step high-speed grinding extraction – Insights into a cut-off value for caffeine abuse
The conclusion is that a new method can measure caffeine and drugs in hair, finding caffeine abusers have 70 times more caffeine than normal, with a proposed cut-off value for abuse.
research Solubilization and Solid‐State Characterization of a Poorly Soluble 5‐α Reductase Inhibitor
GI197111X is best dissolved in Capmul MCM for trials.
research 860 Understanding cellular & molecular responses in the treatment of pediatric lymphatic anomalies
Sirolimus and propranolol may reduce abnormal cell growth and improve lymphatic malformations in children.
research Overview of Ultrasound Imaging Applications in Dermatology
Ultrasound is a useful, non-invasive tool in dermatology for diagnosing skin conditions and guiding treatments, but it has some limitations.