May 2023 in “Journal of Clinical Medicine” New understanding and treatments for hair loss are improving, but more research is needed.
April 2023 in “Journal of Investigative Dermatology” An elderly woman's upper lip lump, thought to be a mucocele, was actually a rare type of lymphoma usually found on legs, treated successfully with chemotherapy and radiation.
March 2026 in “Journal of the mechanical behavior of biomedical materials/Journal of mechanical behavior of biomedical materials” Hair cuticles remain stable and resilient under stress due to strong protein content and crosslinking.
1 citations
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January 2023 in “Burns & Trauma” Wnt4 protein makes the outer skin layer thicker in burn wounds by turning on a specific healing pathway and loosening the connections between skin cells.
19 citations
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March 2017 in “PLoS ONE” PSU are better than THF at regenerating skin layers in lab models.
November 2023 in “npj regenerative medicine” Skin spheroids with both outer and inner layers are key for regrowing skin patterns and hair.
18 citations
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May 2018 in “International Journal of Molecular Sciences” Human body's immune cells are more common in the layer of fat just beneath the skin than in deeper fat layers.
4 citations
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December 2021 in “The journal of investigative dermatology/Journal of investigative dermatology” Overactive Wnt signaling in mouse skin stem cells causes acne-like cysts and shrinking oil glands, which some treatments can partially fix.
1 citations
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October 2012 in “Elsevier eBooks” Skin stem cells can help improve skin repair and regeneration.
25 citations
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August 2011 in “The Journal of Allergy and Clinical Immunology” Finasteride caused a rare skin rash in a man, which improved after stopping the medication.
375 citations
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June 2013 in “Biochimica et biophysica acta. Molecular cell research” Cornification is how skin cells die to form the protective outer layer of skin, hair, and nails.
396 citations
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May 2011 in “Cell stem cell” Nerve signals are crucial for hair follicle stem cells to become skin stem cells and help in wound healing.
211 citations
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May 2018 in “Trends in cell biology” Different types of skin cells play specific roles in development, healing, and cancer.
18 citations
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April 2014 in “Stem cells” The study found stem cells in minor salivary glands that can differentiate and are involved in tumor formation when exposed to tobacco.
31 citations
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May 2019 in “Nature communications” Single Blimp1+ cells can create functional sebaceous gland organoids in the lab.
130 citations
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January 1994 in “Differentiation” Mouse hair follicle cells briefly grow during the early hair growth phase, showing that these cells are important for starting the hair cycle.
15 citations
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September 1999 in “British Journal of Dermatology” Epimorphin, a protein, plays a key role in the development of hair follicles in human fetuses, but it doesn't help in maintaining the stem cell population of the follicular skin layer.
June 2022 in “Research Square (Research Square)” Nestin-expressing cells turn into a specific type of skin cell in hair follicles during development and in adults.
May 2022 in “Research Square (Research Square)” Nestin marks cells that can become a specific type of skin cell in hair follicles of both developing and adult mice.
20 citations
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April 2011 in “Dermatologic Surgery” Laser therapy helped new hair grow in scarred skin for three patients.
139 citations
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December 1998 in “The journal of investigative dermatology/Journal of investigative dermatology” K6hf is a unique protein found only in a specific layer of hair follicles.
83 citations
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May 2013 in “International Journal of Molecular Sciences” Skin development in mammals is controlled by key proteins and signals from underlying cells, involving stem cells for maintenance and repair.
48 citations
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May 1991 in “The journal of investigative dermatology/Journal of investigative dermatology” Trichohyalin is also found in the outer layers of normal human skin.
116 citations
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August 2010 in “Nature” Scientists turned rat thymus cells into stem cells that can help repair skin and hair.
2 citations
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December 2016 in “Experimental cell research” The research found a way to identify and study skin cells with stem cell traits, revealing they behave differently in culture and questioning current stemness assessment methods.
1 citations
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July 1973 in “British Journal of Dermatology” The document concludes that secondary syphilis cases are increasing and often misdiagnosed, pityriasis rubra pilaris can be distinguished from psoriasis by skin cell features, and different skin layers produce specific components during skin repair.
April 2020 in “Journal of animal research” Canine hair follicles have stem cells in the bulge region.
153 citations
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January 2001 in “Science” Using CDK inhibitors on rats showed a reduction in chemotherapy-caused hair loss, but later experiments could not repeat these results.
9 citations
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July 2022 in “Dermatology and Therapy” The laser treatment effectively and safely improved keratosis pilaris.
November 2025 in “Nature Communications” Hair growth may involve a pulling force from the outer root sheath.