21 citations
,
January 1945 in “Journal of Nutrition” Biotin deficiency in monkeys causes fur and skin issues, but 20 μg of biotin daily can prevent or cure it.
2 citations
,
January 1997 in “Journal of Clinical Biochemistry and Nutrition” Biotin deficiency causes severe hair loss and weight reduction in germ-free mice.
5 citations
,
March 2021 in “International Journal of Dermatology” Biotin supplementation during isotretinoin treatment for acne may help maintain skin hydration and improve hair growth.
Biotin boosts wool growth and follicle health in sheep.
8 citations
,
September 1981 in “Zentralblatt für Veterinärmedizin Reihe A” Biotin deficiency in pigs causes hair loss, skin issues, and weak claws.
55 citations
,
November 2019 in “Cellular and Molecular Gastroenterology and Hepatology” Biotin may help treat inflammatory bowel disease by reducing inflammation and improving gut health.
15 citations
,
May 2006 in “Brain & development” Valproic acid may cause hair loss by reducing biotinidase enzyme activity in rats.
January 2025 in “Genetics in Medicine Open” Biotinidase deficiency can mimic neuromyelitis optica and should be considered for accurate diagnosis and treatment.
22 citations
,
September 2008 in “Brain & development” Biotin supplements increased biotin levels but did not significantly prevent hair loss in rats on valproic acid.
1 citations
,
December 2017 in “Skin appendage disorders” Biotin may help women with hair loss who have low biotin levels, but more research is needed.
31 citations
,
February 1983 in “American Journal of Clinical Nutrition” Biotin deficiency can cause hair loss in adults on long-term TPN, but supplementation helps regrow hair.
71 citations
,
January 2016 in “International Journal of Trichology” Biotin deficiency is not a major cause of hair loss in women, so biotin supplements are not likely to be an effective hair loss treatment.
6 citations
,
September 1996 in “Journal of the European Academy of Dermatology and Venereology” Biotin supplements may help hair regrowth in alopecia areata patients with low biotinidase activity.
1 citations
,
September 1996 in “Journal of the European Academy of Dermatology and Venereology” Biotin supplements may help hair regrowth in some alopecia areata patients.
September 2024 in “Meditsinskiy sovet = Medical Council” Biotin effectively treats hair loss, skin, and nail issues without overdose risk.
27 citations
,
July 1946 in “The journal of nutrition/The Journal of nutrition” Biotin and inositol are crucial for pig health and growth.
September 2009 in “European journal of paediatric neurology” Biotin supplements did not significantly reduce hair loss in rats on valproic acid.
73 citations
,
October 2001 in “Epilepsia” Children taking higher doses of valproic acid had lower biotinidase activity, which may lead to biotin deficiency, but biotin supplements could help.
30 citations
,
July 1984 in “Journal of Animal Science” Adding biotin to sows' diets increased the number of pigs weaned per litter.
May 2025 in “Health Science Reports” Serum WS Biotin significantly reduces hair shedding and improves hair thickness.
4 citations
,
August 2018 in “Journal of The American Academy of Dermatology” The authors agree that biotin may help certain hair disorders but lacks evidence for use in healthy people and call for more research.
9 citations
,
February 1984 in “Zentralblatt für Veterinärmedizin Reihe A” Biotin is essential for healthy skin and claws in pigs.
101 citations
,
July 1985 in “Journal of the American Academy of Dermatology” Biotin improved hair growth and combability in one child with uncombable hair syndrome.
Biotin does not significantly help with hair growth.
May 2021 in “Zenodo (CERN European Organization for Nuclear Research)” Biotin may help hair and nails grow.
24 citations
,
May 2017 in “PubMed” Biotin supplements for hair improvement are popular without scientific proof of effectiveness.
August 2018 in “Journal of the American Academy of Dermatology” Biotin treatment for hair, nail, and skin disorders has weak evidence and should not be recommended unless new research shows clear benefits.
11 citations
,
January 1989 in “PubMed” Biotin improved fur and skin conditions in most dogs.
43 citations
,
October 1955 in “The journal of nutrition/The Journal of nutrition” Germ-free rats need biotin for growth and have different vitamin metabolism compared to regular rats.
82 citations
,
August 2017 in “Cell Reports” An imbalanced gut and lack of biotin can cause hair loss in mice.