18 citations
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October 2021 in “Frontiers in Physiology” Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.
June 1998 in “Pathophysiology” Selenium is crucial for health, but both deficiency and excess can cause problems.
September 2024 in “Toxicology Letters” Cortisone and cortisol levels in pregnant women’s hair increase as labor approaches, indicating higher stress.
May 2026 in “Microchemical Journal”
Higher cortisol levels might be linked to worsening keratoconus.
April 2020 in “Journal of the Endocrine Society” Hair cortisol measurement can help diagnose and monitor Cushing’s disease.
5 citations
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June 2020 in “Therapeutic drug monitoring” Hair sample weight is a better measure for cortisol levels in hair than hair protein concentration.
199 citations
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July 2007 in “General and Comparative Endocrinology” Hair cortisol can reliably indicate chronic stress in cats and dogs.
October 2008 in “Experimental and Clinical Endocrinology & Diabetes” Long-term unemployment leads to higher stress levels.
February 2020 in “VSNU Open Access deal” Hair cortisol levels change with age, starting high at birth, decreasing until age 6, then rising to adult levels by age 18.
134 citations
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March 2015 in “Clinical Endocrinology” A new method accurately measures long-term steroid levels in human hair.
85 citations
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January 2014 in “Hormone Research in Paediatrics” Hair cortisol levels in children increase with age but are not affected by gender, puberty, or hair care.
January 2026 in “Open Science Framework” Standardized procedures are needed for accurate hair cortisol analysis.
Hair cortisol content can indicate cortisol exposure and varies with age, puberty, and BMI in youth.
Distal hair cortisol is not a reliable measure of early pregnancy cortisol levels.
August 2016 in “Psychoneuroendocrinology”
May 2016 in “Endocrine Abstracts” Proximal hair cortisol is a reliable tool for diagnosing Cushing's Syndrome.
101 citations
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January 2014 in “Journal of Visualized Experiments” The method effectively measures long-term stress levels using hair samples.
Measuring cortisol in hair can help assess adrenal function in asthmatic children using inhaled corticosteroids.
7 citations
,
April 1992 in “Journal of steroid biochemistry and molecular biology/The Journal of steroid biochemistry and molecular biology” Women with non-classical congenital adrenal hyperplasia have higher levels of certain steroids, which can be reduced by treatment.
May 2019 in “Clinica chimica acta” The study developed methods to measure biomarkers in mice and found differences in hormone levels linked to gut microbiota diversity and stress response.
January 2018 in “Digital Scholarship - UNLV (University of Nevada Reno)” Hair cortisol levels can indicate chronic stress in children, with differences seen between races.
April 2026 in “Frontiers in Veterinary Science” Male cats have higher stress levels than females.
16 citations
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March 2013 in “Clinica Chimica Acta” Cortisol and cortisone release from hair increases in steps over time during incubation.
30 citations
,
July 2016 in “Psychoneuroendocrinology” February 2017 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” Hair cortisol measurement is a promising, non-invasive tool for monitoring cortisol exposure over time.
May 2021 in “Journal of the Endocrine Society” A patient produced cortisol after adrenalectomy, possibly due to residual tissue or other body parts making steroids.
41 citations
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January 2000 in “Hormone Research in Paediatrics” Cortisone reductase deficiency can cause high androgen and cortisol levels and may be missed in women with similar symptoms.
September 2012 in “European journal of psychotraumatology” A new method accurately measures long-term hormone levels in hair.
3 citations
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May 2022 in “Clinical endocrinology” Hair steroid measurement is an effective method to diagnose and monitor CAH in developing countries.