research 11β-Hydroxylase inhibitors protect against seizures in mice by increasing endogenous neurosteroid synthesis
11β-Hydroxylase inhibitors help prevent seizures in mice by boosting natural neurosteroid production.
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research Sulfation of minoxidil by human liver phenol sulfotransferase
Minoxidil activates hair growth by being sulfated by P-PST in the human liver.
research Low-dose oral minoxidil (LDOM) and topical minoxidil: consensus recommendations for managing male and female pattern Hair loss in Hair transplant patients using a modified delphi process
Low-dose oral and topical minoxidil are recommended for managing hair loss in transplant patients, with specific dosing and timing guidelines.
research Cystoid macular oedema in uveitis: An unsolved problem
Treating cystoid macular oedema in uveitis is difficult and risky.
research Characterization of spironolactone and metabolites derivatized using Girard's reagent P using mass spectrometry and ion mobility spectrometry
Girard's reagent P improves detection of spironolactone and its metabolites.
research Monoolein-alginate beads as a platform to promote adenosine cutaneous localization and wound healing
Monoolein-alginate beads help heal wounds by controlling moisture and effectively delivering adenosine to the skin.
research Large doses of glucocorticoid in the treatment of alopecia areata
Large doses of glucocorticoids are not suitable for general use in treating severe alopecia areata due to inconsistent results and risks.
research Supplementary Images & Discussion - Tolerated, Effective, Successful: Low Dose Oral Minoxidil for Treating Alopecia, A 3-Year North American Retrospective Case Series
Low-dose oral minoxidil effectively treats hair loss with good tolerance.
research Disproportionality analysis comparing safety profiles of sonidegib and vismodegib based on the FAERS database
Sonidegib and vismodegib have different side effects and reporting patterns.
research Treatment of hirsutism with spironolactone
Spironolactone is effective and safe for treating excessive facial hair in women.
research Neuroactive steroids inhibit spinal reflex potentiation by selectively enhancing specific spinal GABAA receptor subtypes
Progesterone reduces spinal reflex activity by increasing certain GABA(A) receptor subtypes.
research Miscellaneous Steroids
The document concludes that scientists created various steroids with different properties, including a more effective semi-synthetic vitamin D.
research Recent advances in oxasteroids chemistry
New methods to make oxasteroids show promise for medical treatments like osteoporosis and breast cancer.
research Oral minoxidil 7.5 mg for hair loss increases heart rate with no change in blood pressure in 24 h Holter and 24 h ambulatory blood pressure monitoring
Oral minoxidil 7.5 mg for hair loss increases heart rate but not blood pressure.
research SPIRONOLACTONE CUTS HAIR GROWTH IN IDIOPATHIC HIRSUTISM
Spironolactone reduces hair growth in women with unexplained excessive hairiness.
research Liposomes enhance the hair follicle delivery of minoxidil sulfate with improved treatment of androgenic alopecia
Liposomes improve minoxidil delivery to hair follicles, enhancing treatment for hair loss.
research COMPARATIVE THERAPEUTIC EFFECTS OF ISOLATED THYMOL FROM ORIGANUM MARJORAM ESSENTIAL OIL VERSUS BETAMETHASONE IN CYCLOPHOSPHAMIDE-INDUCED ALOPECIA AREATA IN RABBITS
This study investigated the effects of isolated thymol from Origanum marjoram essential oil compared to betamethasone in treating cyclophosphamide-induced alopecia areata in 50 male rabbits. Thymol, known for its anti-inflammatory and antioxidant properties, was formulated into a spray and applied daily for 14 days. Results showed that thymol led to rapid hair regrowth, reduced inflammation, and significant recovery of dermis thickness (1.8 ± 0.04 mm) compared to betamethasone (1.3 ± 0.02 mm). Histological analysis revealed a well-organized epidermis and abundant follicles in thymol-treated skin, with no necrosis, whereas betamethasone showed moderate improvement with some residual inflammation. The study concludes that thymol is a promising natural alternative for managing alopecia areata, with therapeutic effects comparable to or exceeding those of betamethasone.
research Low-dose oral minoxidil for treating alopecia: A 3-year North American retrospective case series
Low-dose oral minoxidil is an effective and well-tolerated treatment for hair growth in alopecia patients.
research Beyond Boundaries: The Transformative Potential of Spironolactone in Female Pattern Hair Loss
Spironolactone effectively treats female pattern hair loss but requires ongoing use to maintain results.
research Estudio comparativo de dos complementos alimenticios inhibidores de la 5a-reductasa en la alopecia androgénica femenina
The higher dose supplement was more effective in treating female hair loss.
research ISID1077 – Efficacy and safety of ENERGI-F701 solution versus 2% minoxidil solution for female pattern hair loss: a phase II, multi-center, randomized, double-blind, head-to-head, parallel trial
research 76221 Faster Onset and Superior Efficacy of an Investigational Extended-Release Oral Minoxidil Tablet (VDPHL01) Versus Topical and Immediate-Release Oral Minoxidil for Androgenetic Alopecia: Results from a Blinded Retrospective Investigator Global Assessment
research N-Acyl arylsulfonamides as novel, reversible inhibitors of human steroid sulfatase
Scientists found new, better-working inhibitors for a hormone-related enzyme.
research Minoxidil for Control of Acute Blood Pressure Elevation in Chronically Hypertensive Children
Minoxidil, when used with a diuretic and β-blocking agent, can safely lower blood pressure in most children with severe hypertension due to kidney disease, with minimal side effects.
research 60058 Change in patient-reported hair satisfaction during deuruxolitinib treatment of severe alopecia areata: Pooled data from the Phase 3 THRIVE-AA1 and THRIVE-AA2 trials
Deuruxolitinib significantly improves hair satisfaction in severe alopecia areata patients.
research Subcutaneous Injection of Large Volumes of Polidocanol
research A comparative study of Aldactone® and Diane® in the treatment of hirsutism
Aldactone was more effective in reducing hair growth in women with hirsutism than Diane, despite having less impact on hormone levels.
research Evaluation of Antiarthritic and Antinociceptive Effects of Cedrol in a Rat Model of Arthritis
Cedrol may help treat rheumatoid arthritis due to its anti-inflammatory and antioxidant effects.
research Minoxidil Overdose: A Case Report and Review of the Literature
Minoxidil overdose can cause serious side effects, and users should be educated on its safe use.
research Synthesis and characterization of inclusion complex of the vasodilator drug minoxidil with β-cyclodextrin
Minoxidil mixed with β-cyclodextrin improves solubility and gradual release.