research Recurrent pruritic polymorphic lesions associated with weight loss
A man with itchy skin lesions and weight loss was diagnosed with a rare skin condition linked to a pancreatic tumor.
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330-360 / 1000+ results research Localizing the ROS Signal
Localized ROS production is essential for cell growth and movement in plants and animals.
research Local Positive Feedback Regulation Determines Cell Shape in Root Hair Cells
Reactive oxygen species and calcium create a feedback loop that shapes root hair cells.
research Caffeic acid N-[3,5-bis(trifluoromethyl)phenyl] amide as a non-steroidal inhibitor for steroid 5α-reductase type 1 using a human keratinocyte cell-based assay and molecular dynamics
Compound 4 is a promising treatment for hair loss with low toxicity.
research Primary Involvement of NADPH Oxidase 4 in Hypoxia-Induced Generation of Reactive Oxygen Species in Adipose-Derived Stem Cells
NADPH oxidase 4 is key for stem cell activity and growth under low oxygen.
research Efficacy and Safety of an Oral Nutritional (Dietary) Supplement Containing Pinus pinaster Bark Extract and Grape Seed Extract in Combination with a High SPF Sunscreen in the Treatment of Mild-to-Moderate Melasma: A Prospective Clinical Study
The oral supplement with Pinus pinaster and Grape seed extract, used with sunscreen, effectively and safely improved mild-to-moderate facial melasma.
research Shortcutting the diagnostic odyssey: the multidisciplinary Program for Undiagnosed Rare Diseases in adults (UD-PrOZA)
The UD-PrOZA program successfully diagnosed 18% of adult patients with rare diseases, often using genetic testing.
research Exploring the clinical implications of novel SRD5A2 variants in 46,XY disorders of sex development
New SRD5A2 variants may disrupt protein function, aiding diagnosis and treatment of related disorders.
research Unmasking Melasma: Confronting the Treatment Challenges
Melasma treatment is difficult, but combination therapies and personalized plans show promise.
research The role of PEDF in ageing and development: reduction of oxidative damage and support for stem cells
PEDF reduces oxidative damage and supports stem cells.
research Natural Product-Inspired Bis(trifluoromethyl) Phenyl Hydroxycinnamate Derivatives as Promising Nonsteroidal Inhibitors of Human Steroid 5α-Reductase Type-1: Synthesis, In Vitro, and In Silico Studies
New compounds show promise as nonsteroidal treatments for hair loss.
research An overview about Therapeutic uses, clinical efficacy, safety and classes of Retinoids and its efficacy for Treatment of skin aging
Retinoids effectively treat skin aging but have safety and stability issues.
research Potent Antioxidative and UVB Protective Effect of Water Extract ofEclipta prostrataL.
Eclipta prostrata extract protects skin cells from UVB damage and has strong antioxidant properties.
research Hyaluronic Acid Micelles for Promoting the Skin Permeation and Deposition of Curcumin
CUR-loaded micelles improve skin delivery and effects of curcumin for pain and infections.
research The Hair Cycle and Its Relation to Nutrition
research Volume imaging to interrogate cancer cell-tumor microenvironment interactions in space and time
Advanced imaging methods have improved understanding of cancer cell interactions and treatment strategies.
research Functional endoscopy techniques for tracking stem cell fate
Endoscopic imaging can improve tracking of stem cells in the body.
research Types of Human Stem Cells and Their Therapeutic Applications
Stem cells can be reprogrammed for various treatments, but safety and expansion challenges remain.
research Identification of Beta-Sitosterol and Stigmasterol as Possible Inhibitors of 5 Alpha-Reductase 1: An In-Silico Study
Beta-sitosterol and stigmasterol might help prevent hair loss by blocking a specific enzyme.
research Systematic review on Abrus precatorius Linn. since 1871: ethnobotanical uses, phytochemistry and pharmacological properties
Abrus precatorius has medicinal benefits but can be toxic.
research Dynamic evaluation of pathological changes in a mouse acne model by optical imaging technology
New imaging techniques can assess and track changes in mouse acne without harm, aiding treatment choices.
research Atelocollagen Increases Collagen Synthesis by Promoting Glycine Transporter 1 in Aged Mouse Skin
Atelocollagen boosts collagen production and improves skin elasticity in aged skin.
research Medical Technologies: Pharmaceutical Cosmetology, Cosmeceuticals – Opportunities and Limitations
Cosmeceuticals effectively treat skin issues but need better regulation and safety measures.
research Adjunctive Approaches for Androgenetic Alopecia: A Clinical Review of Nutritional, Light-Based, Topical, and Lifestyle Interventions
A holistic approach, including diet and stress management, may improve androgenetic alopecia treatment outcomes.
research 5α-Reductase Isoenzymes: From Neurosteroid Biosynthesis to Neuropsychiatric Outcomes
Finasteride and dutasteride may cause depression and anxiety, especially in younger men.
research Safety First: A Comprehensive Review of Nutritional Supplements for Hair Loss in Breast Cancer Patients
Consult an oncologist before using supplements for hair loss during breast cancer treatment.
research Mitochondrial dysfunction in metabolic syndrome and inflammatory skin disease
Mitochondrial dysfunction links metabolic syndrome and inflammatory skin diseases, suggesting targeted therapies and lifestyle changes.
research 5 Alpha-Reductase Inhibitory Potential of Solanum nigrum Effective for Management of Alopecia
Solanum nigrum may help treat hair loss.
research Androgenetic alopecia: An update
Two drugs, finasteride and minoxidil, are approved for hair loss treatment, but new therapies are being developed.
research From geroprotective tactics to anti-ageing strategy:ways to eliminate ageing per se
The document concludes that aging can be tackled by either slowing it down or eliminating its root cause.