33 citations
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May 1991 in “British Journal of Pharmacology” Cromakalim relaxes various blood vessels, while minoxidil sulphate is more selective; they likely act on different potassium channels.
35 citations
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December 1979 in “Naunyn-schmiedebergs Archives of Pharmacology” These drugs raise prostaglandin-like material in dog blood, possibly causing blood vessel widening.
14 citations
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April 2009 in “Acta Medica Scandinavica” Minoxidil helps control blood pressure but has side-effects, so it's not for everyone.
2 citations
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June 1987 in “British Journal of Dermatology” Warming hands improves blood flow in people with systemic sclerosis.
March 2007 in “Journal of hypertension” Minoxidil effectively lowers blood pressure in patients with resistant hypertension.
13 citations
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January 1987 in “Dermatology” Minoxidil sulfate relaxes blood vessels by increasing potassium permeability.
June 2026 in “arXiv (Cornell University)” Hair beds in fluid show nonlinear response due to viscosity, inertia, and elasticity.
57 citations
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February 1975 in “Journal of Clinical Investigation” Minoxidil boosts plasma renin activity, influenced by control plasma renin activity and changes in sympathetic tone.
20 citations
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February 1977 in “Circulation” Minoxidil lowers blood pressure and increases heart efficiency, but may raise lung artery pressure in some people.
63 citations
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February 2010 in “Journal of Neurophysiology” Microstimulation of certain facial and mouth nerves can evoke specific sensations, while deeper nerves may require multiple stimulations to affect perception.
January 2022 in “Social Science Research Network” Potassium channel modulators mostly increase the activity of rat whisker mechanoreceptors.
March 2025 in “Journal of Cosmetic Dermatology” Botulinum toxin type A may widen certain arteries, but more research is needed.
November 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” Neonatal blood vessels rearrange and stabilize as adults, with adult vessels better at self-repair after injury.
26 citations
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June 1983 in “Journal of Hypertension” Minoxidil lowers blood pressure more effectively but has more side effects, so try hydralazine first.
1 citations
,
October 1974 in “Postgraduate medicine” New drugs like clonidine and prazosin show promise for treating high blood pressure despite some side effects.
19 citations
,
March 1990 in “Journal of Cardiovascular Pharmacology” Minoxidil affects rat fluid dynamics, altering pressure and circulation, improving blood flow and hair growth.
2 citations
,
January 2006 in “PubMed” Carpronium chloride increases blood flow by widening small blood vessels.
25 citations
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December 1974 in “Clinical Pharmacology & Therapeutics” Propranolol affects heart rate and renin levels in minoxidil-treated patients.
3 citations
,
March 2012 in “Arab Journal of Urology” Certain drugs can reduce bladder muscle contractions, potentially helping treat bladder diseases.
48 citations
,
May 2002 in “Journal of Anatomy” VEGFs increase blood vessel permeability, especially in diseases like cancer and heart disease.
February 2025 in “Brazilian Journal of Hair Health” Multiparametric ultrasound effectively monitors scalp changes after using vasoconstrictive cosmetics.
15 citations
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July 1991 in “International Journal of Dermatology” Laser Doppler velocimetry is a valuable noninvasive tool for skin blood flow research in dermatology.
17 citations
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April 1972 in “PubMed” Minoxidil lowers blood pressure and spreads throughout the body in normal rats.
13 citations
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December 2009 in “Journal of the Peripheral Nervous System” TRPA1 and TRPV1 channels don't affect mechanotransduction in rat sinus hair follicles.
50 citations
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September 1975 in “American Heart Journal” Minoxidil effectively controls blood pressure in severe cases, but may cause fluid retention and edema.
October 2025 in “Research Square (Research Square)” Enhancing blood vessel interactions with hair cells may help treat hair loss and skin aging.
Sphingosine 1-phosphate affects inflammation and gene expression in different aorta cells.
March 2021 in “Postepy Dermatologii I Alergologii” Minoxidil works equally well for hair growth regardless of scalp blood flow.
April 2016 in “Journal of Investigative Dermatology” 1 citations
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January 2018 Sphingosine 1-phosphate and its receptor S1PR3 are key in controlling mechanical pain.