research Breaking the ‘rule-of-five’ to access bridged bicyclic heteroaromatic bioisosteres
A new method creates unique chemical structures that could improve drug discovery.
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720-750 / 1000+ results research An Integrated Two-Step Enzymatic Unhairing Strategy: Eliminating the Penetration Barrier via Soaking To Enhance Targeted Protease Action
The new method speeds up leather unhairing and improves quality.
research In vivoreprogramming of wound-resident cells generates skin with hair
Scientists can now create skin with hair by reprogramming cells in wounds.
research JAK-centric explainable few-shot gene-expression diagnosis framework for alopecia via MultiPLIER priors and relation-style set-to-set comparison
A new method helps diagnose alopecia areata using specific gene markers and could guide targeted treatments.
research Forensic DNA Phenotyping
Forensic DNA Phenotyping accurately predicts physical traits and is used in investigations, but needs more diverse population data for confirmation.
research Hand rejuvenation
The hand rejuvenation method makes hands look younger by improving skin and filling out tissues.
research Identification and characterization of the hamster polyomavirus middle T antigen
The hamster polyomavirus middle T antigen is linked to tumors in hamsters and associates with a specific tyrosine kinase.
research Physical and mechanical cues affecting biomaterial-mediated plasmid DNA delivery: insights into non-viral delivery systems
Biomaterials can improve non-viral gene delivery by enhancing DNA uptake and reducing toxicity.
research Pattern Formation
The conclusion is that understanding how patterns form in biology is crucial for advancing research and medical science.
research Inhibiting the cytosolic function of CXXC5 accelerates diabetic wound healing by enhancing angiogenesis and skin repair
Blocking CXXC5 speeds up diabetic wound healing by improving blood vessel growth and skin repair.
research WIZUALIZACJA OBRAŻEŃ ZEWNĘTRZNYCH I WEWNĘTRZNYCH W SZWEDZKIM URZĘDZIE MEDYCYNY SĄDOWEJ Z WYKORZYSTANIEM TOMOGRAFII KOMPUTEROWEJ I TRÓJWYMIAROWYCH MODELI FOTOGRAMETRYCZNYCH
Sweden's forensic medicine is expanding the use of CT and aims to integrate 3D photogrammetry for injury documentation.
research Characteristic intraepidermal nerve fibre endings of the intervibrissal fur in the mystacial pad of the rat: morphological details revealed by intravital methylene blue staining and the zinc iodide‐osmium tetroxide technique
Methylene blue staining effectively reveals detailed nerve structures in rat snouts.
research 1493 Dynamic changes in fibroblast subpopulations drives development of radiation-induced skin fibrosis through the fra/c-jun pathway
Radiation treatment causes skin fibrosis by increasing certain fibroblast subpopulations, but using a c-Jun inhibitor or fat grafting can reduce this effect.
research Modeling cell–cell communication for immune systems across space and time
The document concludes that computational models are useful for understanding immune responses and could improve cancer immunotherapy.
research [Hair follicles and vascular endothelial growth factor].
research The Quantification of Terminal Hair by Digital Microscopy: Advancements Towards a More Objective Diagnosis of Hirsutism
Digital microscopy can help diagnose hirsutism by measuring hair growth.
research Development of finasteride/PHBV@polyvinyl alcohol/chitosan reservoir-type microspheres as a potential embolic agent: from in vitro evaluation to animal study
Created microspheres show potential for safe and effective use in prostate artery embolization.
research Training the Next Generation of Clinician–Innovators: The Virtual Magic Wand Program
The Virtual Magic Wand program successfully trained dermatologists in innovation, with most feeling capable of leading innovation teams and many starting companies.
research Interleukin‐10 Derived Apoptotic Vesicles Enhance Scarless Skin Healing by Modulating Fibroblast Metabolism and Fibrosis Pathways
IL10_ApoEVs improve skin healing and reduce scarring.
research Unique Tumor Heterogeneity Within a Single Locally Advanced Basal Cell Carcinoma Resulting in Partial Response Despite Continuous Vismodegib Treatment
Different tumor cells in one basal cell carcinoma can cause mixed treatment responses, suggesting personalized treatment is needed.
research A Novel Follicular Unit Excision Device for All-Purpose Hair Graft Harvesting
The new hair graft device is faster, more efficient, and reduces damage to hair follicles.
research Fractional microporation-guided delivery of nanoencapsulated drugs for enhanced cutaneous and follicular absorption: a comparison of ablative laser and radiofrequency microneedling
research Laser-Guided Hairline Design and Donor Strip Marking
The document's conclusion cannot be provided as the content is not available.
research Method for chronological recording of antigen appearance in human head-hair shafts and its use for monitoring glycation products in diabetes
The method can help diagnose and monitor diabetes by analyzing hair.
research A Mechanical-assisted Post-bioprinting Strategy for Challenging Bone Defects Repair
The new method improves bone repair by enhancing cell loading and stability in bioprinted scaffolds.
research The global regulatory logic of organ regeneration: circuitry lessons from skin and its appendages
Understanding molecular pathways is key to improving organ regeneration.
research Effects of Fibroblast Transplantation on the Content of Macrophages and the Morphology of Regenerating Ischemic Cutaneous Wounds
Fibroblast transplantation improves wound healing, with dermal equivalents slightly enhancing skin regeneration.
research Molecular mechanisms of viral oncogenesis in humans
Some viruses can cause cancer by changing cell processes and avoiding the immune system; vaccines and targeted treatments help reduce these cancers.
research 3D cell culture stimulates the secretion of in vivo like extracellular vesicles
3D cell cultures produce extracellular vesicles similar to those in the body.
research 555 Dermal single-cell atlas: a novel tool to explore fibroblast heterogeneity
A new tool helps study hair follicle cells to develop better treatments for hair disorders.