56 citations
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January 2015 in “Circulation” Finasteride helps reduce heart issues and improves heart function.
21 citations
,
July 2019 in “Cardiovascular Research” High levels of male hormones in pregnant mice cause heart enlargement and poor heart function in their female babies.
4 citations
,
January 2012 in “International Journal of Cardiology” Dihydrotestosterone (DHT) worsens heart enlargement, and blocking it may help prevent heart issues.
18 citations
,
April 2013 in “PLOS ONE” Mice with autoimmune hair loss showed signs of heart problems.
4 citations
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October 2022 in “American journal of physiology. Heart and circulatory physiology” Higher DHT levels are linked to worse heart changes in severe aortic valve stenosis patients.
47 citations
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May 2020 in “Cardiovascular Research” The document concludes that future heart disease research should account for sex-specific differences to improve diagnosis, treatment, and outcomes.
5 citations
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July 2016 in “Journal of Clinical Hypertension” Men with severe early-onset baldness may have worse heart artery function and stiffer arteries if they have high blood pressure.
2 citations
,
January 2021 in “Cureus” Long-term anabolic steroid use can lead to heart and metabolic health issues.
1 citations
,
October 2025 in “Frontiers in Cardiovascular Medicine” Anabolic-androgenic steroid abuse can cause heart damage and sudden death.
June 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” Male hormones and reduced plakoglobin can impair heart electrical function and increase arrhythmia risk in males.
August 2013 in “Circulation Research” Finasteride reduces heart enlargement and improves heart function.
2 citations
,
August 2023 in “Journal of Endocrinological Investigation” Excess maternal androgens can cause heart problems in offspring.
April 2026 in “Quality in Sport” Anabolic-androgenic steroids increase the risk of heart problems.
January 2021 in “ABC Heart Failure & Cardiomyopathy” When treating older patients with both heart valve disease and heart muscle disease, doctors should create personalized treatment plans that address both conditions.
October 2023 in “BMJ Case Reports” Thyroid hormone therapy effectively treated the man's rare muscle and heart issues.
7 citations
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July 2019 in “Scientific Reports” Finasteride helps reduce heart enlargement in heart failure patients.
The man had myotonia, which caused delayed hand grip relaxation.
59 citations
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November 2010 in “Circulation Research” Wnt signaling may be linked to heart diseases in aging and could be a target for future treatments.
13 citations
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September 2008 in “Experimental and Clinical Endocrinology & Diabetes” Young women with PCOS without additional risk factors may have normal heart function.
May 2020 in “Fertility and Sterility” Nonobese, normotensive Indian women with PCOS may have a higher risk of heart problems linked to inflammation and insulin resistance.
27 citations
,
February 2020 in “Journal of Cardiovascular Translational Research” Women generally handle heart enlargement better than men, but it's riskier for them if it occurs; hormones like estrogen offer some protection.
45 citations
,
October 1988 in “British Journal of Clinical Pharmacology” Using topical minoxidil for baldness can cause heart problems, especially in those with heart disease.
38 citations
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September 2019 in “Chinese Medical Journal” Using steroids can increase the risk of heart problems.
6 citations
,
May 2020 in “Pharmacology Research & Perspectives” A new gel form of minoxidil is equally effective for hair growth and safer for the heart and other organs than the traditional solution.
January 2015 in “Side effects of drugs annual” The document concludes that sex hormones and related compounds have various effects on health, with both potential benefits and risks.
3 citations
,
October 2019 in “EMBO molecular medicine” Targeting NCoR1 can help treat heart enlargement and dysfunction.
October 2018 in “Journal of Clinical Research in Pediatric Endocrinology” Children with classic congenital adrenal hyperplasia have thicker heart fat and more heart and blood vessel risk factors, especially if their condition is not well-controlled.
9 citations
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February 2019 in “Journal of Clinical Research in Pediatric Endocrinology” Children with classic congenital adrenal hyperplasia have thicker heart fat and are at higher risk for heart problems and early atherosclerosis.
7 citations
,
February 2024 in “The Journal of Physiology” Reduced plakoglobin and steroid abuse increase the risk of heart rhythm issues.
January 2020 in “Brazilian Journal of Pharmaceutical Sciences” Finasteride worsens heart damage from nandrolone decanoate but protects against cell damage.