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Induction of Hair Follicle Dermal Papilla Cell Properties in Human Induced Pluripotent Stem Cell-Derived Multipotent LNGFR(+)THY-1(+) Mesenchymal Cells

research Induction of hair follicle dermal papilla cell properties in human induced pluripotent stem cell-derived multipotent LNGFR(+)THY-1(+) mesenchymal cells

42 citations , February 2017 in “Scientific Reports”

Researchers found a way to create cells from stem cells that act like human cells important for hair growth and could be used for hair regeneration treatments.

research De Novo Production of Dermal Papilla Cells during the Anagen Phase of the Hair Cycle

41 citations , June 2010 in “Journal of Investigative Dermatology”

New cells are added to the hair's dermal papilla during the active growth phase.

research Human TSC2-null fibroblast-like cells induce hair follicle neogenesis and hamartoma morphogenesis

36 citations , March 2011 in “Nature Communications”

Cells from a skin condition can create new hair follicles and similar growths in mice, and a specific treatment can reduce these effects.

research A review of adipocyte lineage cells and dermal papilla cells in hair follicle regeneration

35 citations , January 2014 in “Journal of Tissue Engineering”

Cell-based therapies using dermal papilla cells and adipocyte lineage cells show potential for hair regeneration.

research The character “hairless” in the mouse

35 citations , November 1931 in “Journal of Genetics”

Hairless mice lack fur due to a genetic mutation affecting skin response, not hormone issues.

Hair Growth Effects of Oral Administration of Finasteride, a Steroid 5 Alpha-Reductase Inhibitor, Alone and in Combination with Topical Minoxidil in the Balding Stumptail Macaque

research Hair growth effects of oral administration of finasteride, a steroid 5 alpha-reductase inhibitor, alone and in combination with topical minoxidil in the balding stumptail macaque.

34 citations , February 1992 in “The Journal of Clinical Endocrinology and Metabolism”

Finasteride and minoxidil together promote hair growth better than either alone.

Various Wavelengths of Light-Emitting Diode Light Regulate the Proliferation of Human Dermal Papilla Cells and Hair Follicles via Wnt/β-Catenin and the Extracellular Signal-Regulated Kinase Pathways

research Various Wavelengths of Light-Emitting Diode Light Regulate the Proliferation of Human Dermal Papilla Cells and Hair Follicles via Wnt/β-Catenin and the Extracellular Signal-Regulated Kinase Pathways

33 citations , January 2017 in “Annals of Dermatology”

LED light can help hair growth by activating specific cell pathways.

Inhibition of Hair Growth by Testosterone in the Presence of Dermal Papilla Cells from the Frontal Bald Scalp of the Postpubertal Stumptailed Macaque

research Inhibition of Hair Growth by Testosterone in the Presence of Dermal Papilla Cells from the Frontal Bald Scalp of the Postpubertal Stumptailed Macaque¹

33 citations , January 1997 in “Endocrinology”

Testosterone can slow down hair growth when combined with certain cells from bald scalps, and this effect can be blocked by an androgen receptor blocker.

research The Additive Effects of Minoxidil and Retinol on Human Hair Growth in Vitro

32 citations , January 2007 in “Biological & Pharmaceutical Bulletin”

Minoxidil and retinol together help hair grow.

research Use of extracellular matrix hydrogel from human placenta to restore hair-inductive potential of dermal papilla cells

31 citations , August 2019 in “Regenerative Medicine”

Human placenta hydrogel helps restore cells needed for hair growth.

Smad1 and Smad5 but Not Smad8 Establish Stem Cell Quiescence Critical for Transforming Premature Hair Follicles During Morphogenesis to the Postnatal State

research Smad1 and 5 but Not Smad8 Establish Stem Cell Quiescence Which Is Critical to Transform the Premature Hair Follicle During Morphogenesis Toward the Postnatal State

31 citations , September 2013 in “Stem Cells”

Smad1 and Smad5 are essential for hair follicle development and stem cell sleepiness.

research Peppermint Oil Promotes Hair Growth without Toxic Signs

30 citations , December 2014 in “Toxicological Research”

Peppermint oil can effectively promote hair growth without being toxic.

research Responses of hair follicle–associated structures to loss of planar cell polarity signaling

29 citations , February 2013 in “Proceedings of the National Academy of Sciences of the United States of America”

Loss of Fz6 disrupts hair follicle and associated structures' orientation.

research The Basic Science of Hair Biology

29 citations , September 2012 in “Dermatologic Clinics”

Hair disorders are caused by a complex mix of biology, genetics, hormones, and environmental factors, affecting hair growth and leading to conditions like alopecia.

Activation of Beta-Catenin Signaling in CD133-Positive Dermal Papilla Cells Drives Postnatal Hair Growth

research Activation of β-Catenin Signaling in CD133-Positive Dermal Papilla Cells Drives Postnatal Hair Growth

26 citations , July 2016 in “PLOS ONE”

Activating β-catenin in certain skin cells speeds up hair growth in mice.

research Roles of GasderminA3 in Catagen–Telogen Transition During Hair Cycling

25 citations , April 2015 in “Journal of Investigative Dermatology”

GasderminA3 is important for normal hair cycle transitions by controlling Wnt signaling.

research Macrophage-Stimulating Protein Promotes Hair Growth Ex Vivo and Induces Anagen from Telogen Stage Hair Follicles In Vivo

25 citations , June 2004 in “Journal of Investigative Dermatology”

Macrophage-stimulating protein helps hair grow and can start hair growth phase in mice and human hair samples.

research Hair growth in vitro from histocultured skin

25 citations , August 1992 in “In vitro cellular & developmental biology”

The new system can grow hair in the lab and test hair growth treatments.

Poly(γ-Glutamic Acid)/Chitosan Hydrogel Nanoparticles for Effective Preservation and Delivery of Fermented Herbal Extract for Enlarging Hair Bulb and Enhancing Hair Growth

research
Poly(γ-Glutamic Acid)/Chitosan Hydrogel Nanoparticles For Effective Preservation And Delivery Of Fermented Herbal Extract For Enlarging Hair Bulb And Enhancing Hair Growth

22 citations , October 2019 in “International Journal of Nanomedicine”

The nanoparticles improved hair growth and enlarged hair bulbs.

The Effect of Cilostazol, a Phosphodiesterase 3 (PDE3) Inhibitor, on Human Hair Growth with Dual Promoting Mechanisms

research The effect of cilostazol, a phosphodiesterase 3 (PDE3) inhibitor, on human hair growth with the dual promoting mechanisms

21 citations , April 2018 in “Journal of Dermatological Science”

Cilostazol helps hair grow by making hair root cells grow faster and changing growth factor levels.

research Human umbilical cord blood mesenchymal stem cells engineered to overexpress growth factors accelerate outcomes in hair growth

21 citations , January 2018 in “The Korean Journal of Physiology and Pharmacology”

Modified stem cells from umbilical cord blood can make hair grow faster.

research Activation of Wnt/β-catenin signaling is involved in hair growth-promoting effect of 655-nm red light and LED in in vitro culture model

19 citations , February 2018 in “Lasers in Medical Science”

Red light and LED treatments help hair grow by activating a specific cell signaling pathway.

research miR-195-5p Regulates Hair Follicle Inductivity of Dermal Papilla Cells by Suppressing Wnt/β-Catenin Activation

19 citations , January 2018 in “BioMed Research International”

miR-195-5p reduces hair growth ability in cells by blocking a specific growth signal.

research Effect of Ultraviolet Radiation, Smoking and Nutrition on Hair

19 citations , January 2015 in “Current problems in dermatology”

Ultraviolet rays damage hair, smoking may cause hair loss, and good nutrition is important for hair health, but genetics mainly decide hair thickness.

research Epidermal Stem Cells in Hair Follicle Cycling and Skin Regeneration: A View From the Perspective of Inflammation

18 citations , November 2020 in “Frontiers in Cell and Developmental Biology”

Inflammation plays a key role in activating skin stem cells for hair growth and wound healing, but more research is needed to understand how it directs cell behavior.

Pre-Aggregation of Scalp Progenitor Dermal and Epidermal Stem Cells Activates the WNT Pathway and Promotes Hair Follicle Formation In Vitro and In Vivo Systems

research Pre-aggregation of scalp progenitor dermal and epidermal stem cells activates the WNT pathway and promotes hair follicle formation in in vitro and in vivo systems

17 citations , December 2019 in “Stem Cell Research & Therapy”

Grouping certain skin cells together activates a growth pathway that helps create new hair follicles.

A Study of the Expression of Small Conductance Calcium-Activated Potassium Channels (SK1-3) in Sensory Endings of Muscle Spindles and Lanceolate Endings of Hair Follicles in the Rat

research A Study of the Expression of Small Conductance Calcium-Activated Potassium Channels (SK1-3) in Sensory Endings of Muscle Spindles and Lanceolate Endings of Hair Follicles in the Rat

17 citations , September 2014 in “PLoS ONE”

SK2 channels help control sensory signals in rat muscle spindles and hair follicles.

Perspectives on Hair Evolution Based on Comparative Studies on Vertebrate Cornification

research Perspectives on Hair Evolution Based on Some Comparative Studies on Vertebrate Cornification

17 citations , June 2012 in “Journal of experimental zoology. Part B, Molecular and developmental evolution”

Hair in mammals likely evolved from glandular structures, not scales.

research The G60S Connexin43 Mutant Regulates Hair Growth and Hair Fiber Morphology in a Mouse Model of Human Oculodentodigital Dysplasia

17 citations , June 2011 in “The journal of investigative dermatology/Journal of investigative dermatology”

The G60S Connexin43 mutation causes hair growth issues and poor hair quality in mice, similar to human ODDD patients.

research Transplants from balding and hairy androgenetic alopecia scalp regrow hair comparably well on immunodeficient mice

17 citations , May 2003 in “Journal of The American Academy of Dermatology”

Hair from balding and non-balding areas regrows similarly on mice.

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