3 citations
,
January 2013 in “Egyptian Liver Journal” Many young Egyptian women with PCOS also have fatty liver disease, especially if they are overweight and insulin resistant.
218 citations
,
October 2013 in “Proceedings of the National Academy of Sciences of the United States of America” Mice lacking the PPARγ gene in their fat cells had almost no fat tissue, severe metabolic problems, and abnormal development of other fat-related tissues.
November 2016 in “Tesis Doctorals en Xarxa (Consorci de Serveis Universitaris de Catalunya)” The VMH AMPK-SNS-BAT axis may help treat cachexia and obesity.
20 citations
,
July 2013 in “International Journal of Dermatology” Obesity increases the risk of skin infections, inflammatory conditions, and melanoma, but not basal cell carcinoma.
39 citations
,
August 2001 in “Clinical endocrinology” Lean and obese women with PCOS have similar levels of insulin resistance, indicating it's a core aspect of the condition.
August 2021 in “Journal of maternal and child health” Obesity increases the risk of polycystic ovary syndrome and anemia in women who can have children.
42 citations
,
July 2017 in “Scientific Reports” Women with PCOS are more likely to have insulin resistance and obesity, especially those with the most severe type I PCOS.
September 2016 in “Ege tıp dergisi/Ege tıp dergisi :” An 11-year-old obese girl was diagnosed with lipedematous scalp, a condition with swollen scalp tissue usually found in adult women.
1 citations
,
September 2018 in “Vestnik Vitebskogo gosudarstvennogo medicinskogo universiteta” January 2022 in “Menoufia Medical Journal” Obesity can cause various skin problems, with differences in prevalence between males and females.
4 citations
,
September 2024 in “The Egyptian Journal of Internal Medicine” Doctors should watch for and treat hormonal issues in obese patients beyond just diabetes.
June 2021 in “Zenodo (CERN European Organization for Nuclear Research)” Acanthosis nigricans is common in obese individuals, but not significantly linked to obesity type.
MFN2 mutations cause mitochondrial problems, unusual fat distribution, and low leptin despite high body fat.
2 citations
,
January 2014 in “Journal of Integrated Health Sciences” Obesity is strongly linked to the severity of hirsutism in women.
119 citations
,
November 2009 in “Human Reproduction” Women with PCOS and higher androgen levels are more likely to have fatty liver disease.
August 2025 in “Scire Salutis” Obesity can cause acne in kids and teens due to hormonal and metabolic changes.
16 citations
,
April 2012 in “Gynecological Endocrinology” Older obese women with PCOS have higher cardiovascular and metabolic risks despite lower androgen levels.
Adipocytes in atopic dermatitis skin change and worsen inflammation and fibrosis.
May 2023 in “Journal of Cosmetic Dermatology” Being overweight can cause or worsen skin problems in children, some more common in darker skin, and is often linked to insulin resistance.
4 citations
,
May 2023 in “Plastic & Reconstructive Surgery” Adipose tissue helps skin expand by increasing blood vessels and cell growth.
June 2020 in “The journal of investigative dermatology/Journal of investigative dermatology” Different diets change the fat composition in mouse skin, often reducing beneficial omega-3 fatty acids.
23 citations
,
January 2016 in “Journal of Nanjing Medical University” Overweight women with PCOS are more likely to have excess male hormones.
87 citations
,
March 2007 in “Biological Chemistry” Deleting the scd1 gene in mice prevents obesity by disrupting skin lipids and improving heat regulation.
May 2026 in “AlQalam Journal of Medical and Applied Sciences” Ferritin levels may not accurately show iron stores in obese individuals.
11 citations
,
January 2020 in “Medical Journal Armed Forces India” Insulin resistance is a complex condition that can lead to many diseases and has few treatment options.
2 citations
,
June 2024 in “Frontiers in Immunology” 3D cultures can create active macrophages from fat tissue.
May 2026 in “Reviews in Endocrine and Metabolic Disorders” Effective weight loss during pregnancy is crucial for better maternal and fetal health.
A high-fat diet caused severe health problems in female macaques but was reversible with a normal diet, while male macaques reacted differently.
38 citations
,
March 2024 in “World Journal of Experimental Medicine” Obesity worsens wound healing, and more research is needed to understand why.
November 2022 in “International Journal of General Medicine” Women with Polycystic Ovary Syndrome are more likely to have Non-Alcoholic Fatty Pancreas Disease, which is associated with older age, metabolic syndrome, insulin resistance, and high male hormone levels.