January 2025 in “SKIN The Journal of Cutaneous Medicine” Calcipotriol's effectiveness for treating alopecia areata is unclear and needs more research.
December 2024 in “International Journal of Advanced Research” Metformin and vitamin D3 help manage insulin resistance and hormonal imbalances in obese PCOS patients.
April 2024 in “Nepal journal of dermatology, venereology & leprology” Vitamin D is important for skin health and can help treat and prevent various skin conditions.
1533 citations
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October 2008 in “Endocrine reviews” Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.
119 citations
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July 2016 in “Annals of the New York Academy of Sciences” Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.
30 citations
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October 2009 in “Journal of Veterinary Internal Medicine” A Pomeranian dog had rickets due to a new gene mutation, leading to severe symptoms and euthanasia.
2 citations
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August 2022 in “Clinical Case Reports” A 17-year-old girl had severe, on-and-off hair loss, likely due to COVID-19. She was treated with Vitamin D3, biotin, and other supplements, and saw some improvement within a month.
13 citations
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April 2018 in “Journal of The American Academy of Dermatology” People with certain types of hair loss, especially lichen planopilaris and telogen effluvium, as well as African Americans, Asians, and men, are more likely to have severe vitamin D deficiency.
Vitamin D3 is crucial for health, preventing issues like bone disorders and hair loss.
17 citations
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May 2018 in “Journal of Cosmetic Dermatology” Most women in the study lost hair due to chronic shedding, with stress and nutrient deficiencies being common factors.
5 citations
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May 2023 in “Frontiers in immunology” Environmental factors like diet and vitamin levels, especially Vitamin D, can affect autoimmune diseases differently, with lifestyle changes potentially improving outcomes.
April 2023 in “Clinical Chemistry and Laboratory Medicine” The document concludes that inflammation markers can be used in diabetes, vitamin D3 affects immune pathways, hyperthyroidism changes hormone levels, androgen levels help diagnose Adrenocortical Carcinoma, erectile dysfunction is linked to diabetes, hypogonadism is common in HIV-infected males, and hormones can be biomarkers for various conditions.
10 citations
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February 2017 in “Hormone Molecular Biology and Clinical Investigation” Metformin effectively improves metabolic symptoms in women with PCOS, while alfacalcidiol does not have a significant impact.
December 2025 in “Zenodo (CERN European Organization for Nuclear Research)” Hair loss is caused by diet, hormones, and scalp issues, worsened by COVID-19, with treatments like minoxidil and hair transplants available.
December 2025 in “Zenodo (CERN European Organization for Nuclear Research)” Hair loss is caused by nutritional deficiencies, hormonal imbalances, and stress, with treatments like minoxidil and hair transplants available.
16 citations
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October 1987 in “British journal of dermatology/British journal of dermatology, Supplement” A vitamin D3 compound can reduce skin cell growth.
16 citations
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February 2005 in “British journal of dermatology/British journal of dermatology, Supplement” Lack of Vitamin D receptor changes skin structure and increases certain immune cells in the skin.
47 citations
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September 2023 in “Pharmacological Reports” Vitamins A, B3, C, D, and E can improve skin health and immunity.
6 citations
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August 1989 in “European journal of pediatrics” Child with rickets improved with a specific vitamin D therapy, but alopecia did not change.
59 citations
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April 2016 in “Breast Cancer Research and Treatment” Targeting vitamin D and androgen receptors may effectively treat triple-negative breast cancer, especially with chemotherapy.
2 citations
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September 2022 in “Bioscientia medicina” Topical vitamin D is effective in treating vitiligo with few side effects.
29 citations
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December 2017 in “International Journal of Dermatology” People with alopecia areata often have lower vitamin D levels, which are linked to more severe and longer-lasting hair loss, but vitamin D receptor levels in the skin don't show the same pattern and don't predict treatment success.
17 citations
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April 2007 in “Kidney international” Vitamin D boosts a specific gene activity in kidney cells that could improve heart and kidney function.
4 citations
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May 2021 in “Molecules” The hair test for vitamin D could be a useful alternative to blood tests, providing a longer-term vitamin D status, but more research is needed.
Adequate vitamin D might lower, and high hair chromium might increase DNA damage in obese women.
3 citations
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March 2019 in “Fayoum University Medical Journal/Fayoum University Medical Journal ” Rubbing calcipotriol on the skin works better than taking vitamin D pills for treating mild to moderate alopecia areata.
50 citations
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October 1986 in “European journal of pediatrics” A boy with severe Vitamin D-resistant rickets did not respond to treatment and lacked a common symptom, suggesting a need for alternative treatments.
PCOS patients, especially obese ones, often lack vitamin D and may need supplements and lifestyle changes.
98 citations
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February 2010 in “Dermatology Online Journal” Vitamin D may help treat hair disorders.
May 2025 in “Journal of the Egyptian Womenʼs Dermatologic Society” Vitamin D3 is a safe and effective alternative to steroids for treating alopecia areata, with fewer side effects.