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Did you mean Voltage-Dependent Anion Channel 1?

GlossaryVoltage-Dependent Anion Channel 1

regulates ion flow in mitochondrial outer membrane

Voltage-Dependent Anion Channel 1 (VDAC1) is a protein found in the outer membrane of mitochondria, the energy-producing structures in cells. It acts as a gatekeeper, regulating the flow of ions and small molecules in and out of the mitochondria, which is crucial for cellular energy production and metabolism.

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Cyanidin 3-O-Arabinoside Suppresses DHT-Induced Dermal Papilla Cell Senescence by Modulating p38-Dependent ER-Mitochondria Contacts

research Cyanidin 3-O-arabinoside suppresses DHT-induced dermal papilla cell senescence by modulating p38-dependent ER-mitochondria contacts

14 citations , March 2022 in “Journal of Biomedical Science”

Cyanidin 3-O-arabinoside may help treat a common form of hair loss by protecting cells against aging and improving cell function.

OsUEV1B, a Ubc Enzyme Variant Protein, Is Required for Phosphate Homeostasis in Rice

research OsUEV1B, an Ubc enzyme variant protein, is required for phosphate homeostasis in rice

4 citations , February 2021 in “Plant journal”

OsUEV1B protein is essential for controlling phosphate levels in rice.

research Intracellular Calcium Mobilization in Response to Ion Channel Regulators via a Calcium-Induced Calcium Release Mechanism

19 citations , December 2016 in “The journal of pharmacology and experimental therapeutics/The Journal of pharmacology and experimental therapeutics”

Certain drugs increase calcium levels in cancer cells by triggering internal calcium release.

research Faculty Opinions recommendation of The Venus flytrap trigger hair-specific potassium channel KDM1 can reestablish the K+ gradient required for hapto-electric signaling.

December 2020 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature”

The KDM1 gene helps Venus flytraps close by managing potassium ions.

research Emerging Roles for Ion Channels in Ovarian Cancer: Pathomechanisms and Pharmacological Treatment

29 citations , February 2021 in “Cancers”

Ion channels play a key role in ovarian cancer growth and treatment resistance.

research Pharmacological Inhibition of Stearoyl CoA Desaturase in the Skin Induces Atrophy of the Sebaceous Glands

25 citations , February 2013 in “The journal of investigative dermatology/Journal of investigative dermatology”

Blocking SCD1 in the skin with XEN103 shrinks sebaceous glands in mice.

research Potassium channel openers: pharmacological and clinical aspects

119 citations , October 1992 in “Fundamental & Clinical Pharmacology”

Potassium channel openers could help treat cardiovascular diseases and asthma but require better targeting to specific tissues for effective use.

research TRP Channels in Skin Biology and Pathophysiology

124 citations , December 2016 in “Pharmaceuticals”

TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.

research Minoxidil opens mitochondrial K_ATP channels and confers cardioprotection

28 citations , January 2004 in “British Journal of Pharmacology”

Minoxidil protects heart and improves recovery.

research STABILITY INDICATING AN LC-ESI-MS/MS METHOD FOR THE QUANTIFICATION OF MINOXIDIL IN PHARMACEUTICAL DOSAGE FORMS

January 2026 in “International Journal of Applied Pharmaceutics”

The method accurately measures Minoxidil in drugs and is reliable for routine use.

Persistent Erectile Dysfunction After Discontinuation of 5-Alpha Reductase Inhibitor Therapy in Rats Depending on the Duration of Treatment

research Persistent Erectile Dysfunction after Discontinuation of 5-Alpha Reductase Inhibitor Therapy in Rats Depending on the Duration of Treatment

17 citations , December 2018 in “The World Journal of Men s Health”

Long-term use of dutasteride can cause permanent erectile dysfunction in rats.

A Thallium-Based Screening Procedure to Identify Molecules That Modulate the Activity of Ca2+-Activated Monovalent Cation-Selective Channels

research A Thallium-Based Screening Procedure to Identify Molecules That Modulate the Activity of Ca2+-Activated Monovalent Cation-Selective Channels

5 citations , January 2018

The conclusion is that a new test was created to find substances that affect specific ion channels, and it works well for drug discovery.

research Physical methods for topical skin drug delivery: concepts and applications

22 citations , November 2018 in “Brazilian Journal of Pharmaceutical Sciences”

New physical methods like electrical currents, ultrasound, and microneedles show promise for improving drug delivery through the skin.

research Baiting Proteins with C₆₀

106 citations , April 2010 in “ACS Nano”

C60 fullerenes can alter protein function and may help develop new disease inhibitors.

research The action of diazoxide and minoxidil sulphate on rat blood vessels: a comparison with cromakalim

86 citations , July 1990 in “British Journal of Pharmacology”

Diazoxide, minoxidil sulphate, and cromakalim relax rat blood vessels by opening K+ channels, with some differences in their actions.

research Unlocking the therapeutic potential of TRPV3: Insights into thermosensation, channel modulation, and skin homeostasis involving TRPV3

10 citations , May 2024 in “BioEssays”

TRPV3 is important for skin health and could be a target for treating skin diseases.

research TRPV3 Ion Channel: From Gene to Pharmacology

2 citations , May 2023 in “International Journal of Molecular Sciences”

The TRPV3 ion channel is important for skin and hair health and could be a target for treating skin conditions.

research Towards the Development of AgoKirs: New Pharmacological Activators to Study Kir2.x Channel and Target Cardiac Disease

9 citations , August 2020 in “International Journal of Molecular Sciences”

New compounds may help treat heart disease by activating specific potassium channels.

research Development and evaluation of crystalline inclusion complex of finasteride using electrospraying as a novel approach

2 citations , July 2020 in “Journal of Drug Delivery Science and Technology”

Created finasteride complex to increase water solubility and drug release.

Endocrinology Overview: Male Reproductive Endocrinology and HPT Axis

research Endocrinology Overview RSS

January 2018 in “Elsevier eBooks”

The document explains how male reproductive hormones work and affect the body.

CPK1 Activates CNGCs Through Phosphorylation for Calcium Signaling to Promote Root Hair Growth in Arabidopsis

research CPK1 activates CNGCs through phosphorylation for Ca2+ signaling to promote root hair growth in Arabidopsis

January 2025 in “Nature Communications”

CPK1 helps root hair growth in Arabidopsis by activating channels for calcium signaling.

research Fibroblast bioelectric signaling drives hair growth

3 citations , August 2025 in “Cell”

Fibroblast bioelectric signaling can promote hair growth and may help treat hair loss.

research The Multifaceted Functions of TRPV4 and Calcium Oscillations in Tissue Repair

1 citations , January 2024 in “International journal of molecular sciences”

TRPV4 helps cells repair tissue and reduce scarring by controlling calcium levels.

research Nitric Oxide: Physiological Functions, Delivery, and Biomedical Applications

10 citations , August 2023 in “Advanced Science”

Nitric Oxide has potential in medicine, especially for infections and heart treatments, but its short life and delivery challenges limit its use.

research Exogeneous metal ions as therapeutic agents in cardiovascular disease and their delivery strategies

24 citations , November 2023 in “Regenerative Biomaterials”

Metal ions can help treat heart diseases by protecting cells and repairing tissues.

research Role of Endolysosomes in Severe Acute Respiratory Syndrome Coronavirus-2 Infection and Coronavirus Disease 2019 Pathogenesis: Implications for Potential Treatments

55 citations , October 2020 in “Frontiers in Pharmacology”

Targeting endolysosomes may help treat COVID-19.

research Pathogenesis and management of TRPV3-related Olmsted syndrome

December 2024 in “Frontiers in Genetics”

EGFR and mTOR inhibitors may help manage Olmsted syndrome symptoms.

research Transdermal film-loaded finasteride microplates to enhance drug skin permeation: Two-step optimization study

30 citations , March 2016 in “European Journal of Pharmaceutical Sciences”

Optimized film improves finasteride skin absorption and treatment efficiency.

Expression and Roles of Steroidogenic Acute Regulatory (StAR) Protein in Non-Classical, Extra-Adrenal, and Extra-Gonadal Cells and Tissues

research Expression and roles of steroidogenic acute regulatory (StAR) protein in ‘non-classical’, extra-adrenal and extra-gonadal cells and tissues

48 citations , February 2013 in “Molecular and Cellular Endocrinology”

The protein StAR is found in 17 different organs and can affect hair loss and brain functions, but its full role is not yet fully understood.

research Diuretics

1 citations , September 2017 in “Elsevier eBooks”

Diuretics help the body get rid of excess salt and water by acting on the kidneys in different ways.