research Molecular mechanisms of androgenetic alopecia
AGA causes hair loss by shrinking hair follicles due to DHT binding, and can be treated with finasteride and minoxidil.
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30 / 1000+ results research Mixture effects of endocrine disrupting compounds in vitro
Weak endocrine disruptors in mixtures can have significant effects and should be considered in risk assessments.
research Anti-Androgen Effects of Extracts and Compounds fromGanoderma lucidum
Ganoderma lucidum may help treat prostate cancer by blocking male hormones and slowing cancer cell growth.
research Platelet-rich plasma for the treatment of alopecia: a systematic review and meta-analysis.
PRP might help with hair growth, but the evidence is weak.
research Male androgenetic alopecia
DHT, a testosterone byproduct, causes male pattern baldness.
research Androgen Levels and Body Size Are Associated with Directional as Well as Fluctuating Asymmetry Patterns in Adult !Kung San and Kavango Males from Northern Namibia
Higher androgen levels are linked to less asymmetry in !Kung San males.
research Plättchenreiches Plasma (PRP) zur Behandlung der androgenetischen Alopezie (AGA): ein aktueller Literaturüberblick
PRP may help with hair loss, but more research is needed.
research Probing androgen receptor co-factor selectivity profiles: a chemical tool to determine cross-talk between androgen receptor and β-catenin in vivo
PF-05314882 selectively activates androgen receptors without much effect on prostate and may help in prostate cancer treatment and hair loss prevention.
research Female Androgenetic (?) Alopecia
Female pattern hair loss is different from male pattern hair loss and has unclear genetic causes.
research Biological Profile of Cortexolone 17a-Propionate (CB-03-01), a New Topical and Peripherally Selective Androgen Antagonist
CB-03-01 is a promising skin cream for treating hormone-related skin problems without causing harmful body-wide effects.
research Flow cytometric analysis of cell cycle kinetics of anagen scalp hair correlated with plasma androgens in hirsutism.
Higher DHEA-S levels in hirsute females affect hair growth phases.
research The first broad replication study of SNPs and a pilot genome‐wide association study for androgenetic alopecia in Asian populations
Two specific genetic markers increase the risk of hair loss in Asian populations.
research Steroid Chemistry and Hormone Controls during the Hair Follicle Cycle
Differences in enzyme activity and androgen receptors in hair follicles may explain why hair loss appears differently in men and women.
research Role of Dehydroepiandrosterone and Dehydroepiandrosterone Sulfate for the Maintenance of Axillary Hair in Women
DHEA and DHEA-S help maintain underarm hair in older women.
research Other Antiandrogens
Spironolactone works well for acne and hirsutism, isotretinoin is very effective for acne and may have antiandrogenic effects, and 5 alpha-reductase inhibitors should be considered antiandrogens.
research The lack of significant changes in scalp hair follicle density with advancing age
Aging alone barely affects the number of hair follicles, meaning hair loss is minimal without other conditions like androgenetic alopecia.
research [Hormonal interaction and hair growth].
Hormones, especially DHT, affect hair loss and growth, and targeting specific enzymes may help treat hair loss.
research A new target for squamous cell skin cancer?
Prostaglandins and the enzyme AKR1C3 could play a role in skin cancer and hair loss, and further research is needed to understand these mechanisms.
research [Hyperandrogenism and pilosebaceous follicles].
High levels of androgens can cause skin issues like acne, hair loss, and excessive hair growth.
research Synthesis and in Vitro Evaluation of 4-Substituted N-(1,1-Dimethylethyl)-3-oxo-4-androstene-17.beta.-carboxamides as 5.alpha.-Reductase Inhibitors and Antiandrogens
The new compounds moderately block a specific enzyme and strongly counteract a male hormone, suggesting potential for treating certain male-related health conditions.
research Mechanism of action of bolandiol (19-nortestosterone-3β,17β-diol), a unique anabolic steroid with androgenic, estrogenic, and progestational activities
Bolandiol, a synthetic steroid, builds muscle and bone without greatly affecting sex glands, and works differently from other hormones.
research Pharmacological Options for Treatment of Hyperandrogenic Disorders
Different drugs can treat high male hormone levels in women, but they have various effects and some may harm a fetus.
research Androgenic alopecia in men: the significance of genetic, hormonal and metabolic factors (prospective cohort comparative study)
Androgenic alopecia in men is mainly linked to family history, hormonal imbalances, and metabolic issues, but can also be influenced by lifestyle habits, environmental factors, and deficiencies in certain vitamins and microelements like copper.
research Healthy Hair: What Is it?
Healthy hair is shiny, smooth, and has clean ends.
research Sex hormone levels and body hair growth in !Kung San and Kavango men from Namibia
Lower DHT levels lead to more body hair growth.
research Evaluation and Treatment of Hirsutism in Premenopausal Women
Treat hirsutism in premenopausal women with oral contraceptives and consider additional treatments if needed.
research Hair Transplantation for Frontal Fibrosing Alopecia: Part of the Solution?
Hair transplantation for Frontal Fibrosing Alopecia may work if done after the disease is inactive for 2 years and with ongoing treatment after surgery.
research Platelet-Rich Plasma
Platelet-rich plasma may help with wound healing, hair growth, and skin rejuvenation, but more research is needed to prove its effectiveness.
research Mesotherapy and platelet-rich plasma for the treatment of hair loss
Mesotherapy and platelet-rich plasma treatments may help with hair loss, but their safety and effectiveness are still uncertain.
research Serum ferritin and hair iron content in correlation to hair diameter and density: a case-control study
Hair iron levels might help increase hair thickness in early hair loss.