February 2022 in “Mediators of Inflammation” Women with Polycystic Ovary Syndrome (PCOS) have lower levels of a substance called DIAPH1 in their blood, which is linked to changes in sugar metabolism and insulin resistance.
November 2021 in “Journal of Gandhara Medical and Dental Science” Oral Minoxidil effectively treats male pattern baldness.
November 2022 in “Frontiers in Medicine” Severe hair loss in Chinese men is linked to high blood pressure, while in women, it's linked to larger waist size and cholesterol issues.
189 citations
,
July 2009 in “The Journal of clinical investigation/The journal of clinical investigation” Epidermolysis bullosa simplex causes easily blistered skin due to faulty skin cell proteins, leading to new treatment ideas.
186 citations
,
December 2012 in “Current opinion in cell biology” Keratin proteins are increasingly recognized as important for cell health and are linked to many diseases.
75 citations
,
March 2023 in “JAMA Dermatology” Alopecia areata and its severe forms are becoming more common, especially among females, adults, and people in the Northeast.
26 citations
,
April 2024 in “Particle and Fibre Toxicology” Nanoplastics can penetrate skin cells, triggering inflammation and immune responses.
2 citations
,
February 2021 in “Journal of comparative pathology” Sheep with chronic Sarcoptes scabiei dermatitis have altered keratin expression in their skin.
December 2025 in “IntechOpen eBooks” BMI is not enough for assessing obesity in women; use more personalized tools.
277 citations
,
February 2013 in “Science Signaling” Mitochondrial reactive oxygen species are essential for skin and hair development.
266 citations
,
January 2016 in “Development” YAP and TAZ are crucial for skin cell growth and repair.
101 citations
,
October 2007 in “Journal of Biological Chemistry” Reduced matriptase activity causes skin and hair issues in both humans and mice.
65 citations
,
November 2013 in “The EMBO Journal” HDAC1 is crucial for skin development and preventing tumors.
61 citations
,
January 2011 in “PloS one” Notch signaling is essential for healthy skin and hair follicle maintenance.
50 citations
,
April 2019 in “Journal of Biosciences” 49 citations
,
August 1999 in “Journal of Investigative Dermatology” Overexpressing the MSX-2 gene in mice causes skin and hair growth issues.
44 citations
,
July 2016 in “Stem Cells Translational Medicine” Scientists discovered that certain stem cells from mice and humans can be used to grow new hair follicles and skin glands when treated with a special mixture.
38 citations
,
December 2006 in “Journal of Investigative Dermatology” Keratin patterns in hair follicles help understand hair growth and potential hair and nail disorders.
37 citations
,
August 2024 in “Current Issues in Molecular Biology” Keratins 6, 16, and 17 increase in damaged or diseased skin and may help diagnose skin issues.
34 citations
,
August 2019 in “Journal of Allergy and Clinical Immunology” mTORC2 is crucial for healthy skin barrier by regulating lipids and filaggrin.
33 citations
,
October 2013 in “PloS one” Human sweat glands have a type of stem cell that can grow well and turn into different cell types.
30 citations
,
August 2008 in “The journal of investigative dermatology/Journal of investigative dermatology” TGase 3 helps build hair structure by forming strong bonds between proteins.
29 citations
,
February 2001 in “Proceedings of the National Academy of Sciences” A specific DNA region controls skin cell gene expression by working with certain proteins.
24 citations
,
May 2015 in “Molecular and clinical oncology” Honey and bee pollen can help reduce menopausal symptoms in breast cancer patients.
20 citations
,
November 2003 in “American Journal Of Pathology” Fibroblasts from healthy donors can prevent changes seen in recessive epidermolysis bullosa simplex.
18 citations
,
January 2022 in “Clinical Epidemiology” Higher doses of glucocorticoids increase the risk of blood clots in asthma patients.
15 citations
,
March 2018 in “Cancer Medicine” Alopecia areata patients have varied cancer risks, with some cancers being lower and others higher.
14 citations
,
May 2022 in “Frontiers in Endocrinology” Lower testosterone levels increase kidney stone risk in men over 40.
14 citations
,
March 2016 in “Mechanisms of Development” Basonuclin 2 is vital for the development of facial bones, hair follicles, and male germ cells in adult mice, and its absence can lead to dwarfism and abnormal follicles.
14 citations
,
March 2015 in “Stem Cell Research & Therapy” ABCG2 protein marks stem-like skin cells in human epidermis.