March 2026 in “Annals of Medicine” Standardized tools and treatments are needed to better manage long COVID-19 in kids and teens.
September 2025 in “Immunological Reviews” The skin can independently form immune responses through special structures, offering new ways to treat skin diseases.
lncRNA MRPS28 regulates hair follicle development in cashmere goats, affecting cashmere quality.
January 2025 in “Research” Cellular senescence can both hinder and promote hair growth, suggesting new ways to treat hair loss.
August 2024 in “Current Protocols” The C3H/HeJ mouse model is useful for studying and testing treatments for alopecia areata.
January 2020 in “Indian Journal of Pharmaceutical Sciences” Natural products show promise for new hair loss treatments.
296 citations
,
October 2018 in “General and Comparative Endocrinology” Hair cortisol is a reliable way to measure long-term stress in animals.
3 citations
,
September 2014 in “SpringerPlus” Human hair loss may have evolved to help increase brain size.
2 citations
,
March 2022 in “Applied sciences” Lespedeza bicolor extract promotes hair growth and increases hair follicle cell growth, potentially making it a better treatment than minoxidil.
March 2024 in “Journal of functional foods” Collagen peptides from marine and bovine sources may help prevent hair loss by affecting hair follicle stem cells differently.
489 citations
,
November 2021 in “Signal Transduction and Targeted Therapy” The JAK/STAT pathway is important in cell processes and disease, and JAK inhibitors are promising for treating related conditions.
305 citations
,
March 2008 in “AJP Endocrinology and Metabolism” SSAT is a key enzyme affecting cell growth and metabolism, with potential but risky use in disease treatment.
283 citations
,
February 2011 in “Cell stem cell” COL17A1 is crucial for preventing hair graying and loss by supporting hair and pigment stem cells.
November 2025 in “Bioactive Materials” TQC shows promise for better hair regrowth in treating hair loss.
Lack of Fgf21 slows hair growth by affecting gene interactions.
October 2020 in “Stem cells” The document concludes that DNA methylation and the mTOR pathway are important for stem cell function and could impact disease treatment.
11 citations
,
February 2023 in “Journal of Investigative Dermatology” Low m6Ascores in melanoma predict better survival and response to immunotherapy.
August 2024 in “Cell Death and Disease” Activating TLR9 helps heal wounds and regrow hair by using specific immune cells.
949 citations
,
January 2001 in “Cell” Adult mouse skin contains stem cells that can create new hair, skin, and oil glands.
503 citations
,
May 2009 in “Cell stem cell” Lrig1 marks a unique group of stem cells in mouse skin that can become different skin cell types.
321 citations
,
January 2012 in “Cell stem cell” TGF-β2 helps activate hair follicle stem cells by counteracting BMP signals.
318 citations
,
January 2022 in “Signal Transduction and Targeted Therapy” The Wnt/β-catenin pathway is important for body functions and diseases, and targeting it may treat conditions like cancer, but with safety challenges.
238 citations
,
April 2012 in “Cell stem cell” Targeting and modifying the stem cell niche can improve regenerative therapies.
151 citations
,
August 2011 in “The EMBO Journal” The enzyme PA-PLA1α is important for proper hair follicle development.
124 citations
,
January 2012 in “Journal of Allergy and Clinical Immunology” Endocannabinoids help control mast cell activity in human skin.
106 citations
,
August 2021 in “Pharmaceuticals” Extracellular vesicles help heal skin wounds and could be used for better treatments.
99 citations
,
January 2004 in “Progress in brain research” Neurotrophins are important for hair growth and could help treat hair loss.
91 citations
,
June 2011 in “The EMBO Journal” TCF/Lef1 activity is essential for proper skin cell development and renewal.
81 citations
,
September 2009 in “Birth defects research” Different body areas in mice produce different hair types due to interactions between skin layers.
75 citations
,
February 2017 in “Aging” SkQ1 antioxidant improved health and lifespan in mice.