May 2020 in “Plastic and Aesthetic Research” Endoscopic facial rejuvenation is key for natural, long-lasting results with less scarring and quick recovery.
26 citations
,
September 2023 in “Bioengineered” Brown seaweed oligosaccharides have health benefits and potential uses in food and medicine.
10 citations
,
March 2024 in “Frontiers in Bioengineering and Biotechnology” Photothermal hydrogels can kill bacteria and help heal tissue using light-converted heat.
108 citations
,
January 2003 in “Journal of Cosmetic Dermatology” Wrinkles form due to structural skin changes and vary in type and treatment response.
52 citations
,
November 2006 in “International Journal of Cosmetic Science” Different types of wrinkles need specific treatments.
48 citations
,
October 2010 in “Archives of Dermatological Research” Juvéderm fillers effectively reduce wrinkles for up to 21 months with less filler needed for repeat treatments.
15 citations
,
February 2015 in “Han-gug chugsan sigpum hag-hoeji/Korean journal for food science of animal resources” Egg shell membrane hydrolysates can reduce wrinkles and improve skin health.
4 citations
,
July 2024 in “Cureus” The treatment improved neck wrinkles and skin laxity.
3 citations
,
July 2022 in “Dermatologic Therapy” Magnesium microneedle patches can safely improve under-eye wrinkles when used every other night for 12 weeks.
September 2017 in “Journal of aesthetic nursing” The main treatments for wrinkle reduction are botulinum toxin, dermal fillers, radiofrequency, and ultrasound.
November 2025 in “BMC Genomics” Wrinkled skin in Xiang pigs is linked to gene changes related to oxidative stress and the extracellular matrix.
July 2024 in “Journal of Investigative Dermatology” Topical sulforaphane reduces pigmentation and wrinkles from sun damage.
7 citations
,
June 2024 in “Skin Research and Technology” Combining treatments significantly reduces dark circles and wrinkles better than nanofat alone.
74 citations
,
June 2018 in “Cell death and disease” Restoring mitochondrial function in mice reversed their skin wrinkling and hair loss.
17 citations
,
February 2023 in “Cosmetics” 3D printed hollow microneedles could effectively treat skin wrinkles with fewer side effects.
5 citations
,
September 2013 in “BMB Reports” BMPR1a-ECD reduces wrinkles much more effectively than retinoic acid.
5 citations
,
April 2013 in “Journal of Cosmetic and Laser Therapy” Argireline significantly reduces wrinkles.
1 citations
,
January 2025 in “Dermatologic Therapy” Monopolar radiofrequency effectively reduces facial wrinkles with minimal side effects.
March 2024 in “Intisari Sains Medis” PRP injections improve periorbital wrinkles and show promise as a treatment.
80 citations
,
November 2009 in “Aesthetic Surgery Journal” Women have more and deeper mouth wrinkles than men due to fewer skin appendages.
12 citations
,
January 2016 in “Skin appendage disorders” Repeated botulinum toxin injections for forehead wrinkles may cause hairline recession in some women.
September 2019 in “Journal of Investigative Dermatology” Retinol significantly reduces neck wrinkles.
3 citations
,
September 2019 in “Skin appendage disorders” Women with Frontal Fibrosing Alopecia have more wrinkles near their ears than similar aged women without the condition.
January 2020 in “Elsevier eBooks”
April 2016 in “Journal of Investigative Dermatology” A peptide known for reducing wrinkles also effectively inhibits an enzyme linked to skin inflammation and acne.
11 citations
,
July 2021 in “Genetics selection evolution” Researchers found genes and genetic variants linked to sheep wool and skin wrinkles.
10 citations
,
January 2024 in “Dermatology Research and Practice” Taking a collagen and vitamin C supplement improves skin and hair health.
269 citations
,
October 2018 in “International journal of biological macromolecules” Hyaluronic acid is effective for skin rejuvenation and should be a key ingredient in cosmetic products.
180 citations
,
January 2003 in “American Journal of Clinical Dermatology” Menopause can lead to skin and hair problems due to hormonal changes, but hormone replacement therapy might help slow these effects.
175 citations
,
November 2009 in “PLOS ONE” Women look young for their age due to larger lips, less sun damage, and genes that prevent gray hair and wrinkles.