4 citations
,
July 2024 in “Cureus” The treatment improved neck wrinkles and skin laxity.
5 citations
,
September 2023 in “Nutrients” Soy protein with isoflavones reduces wrinkles and improves skin hydration in postmenopausal women.
1 citations
,
October 2025 in “Plastic & Reconstructive Surgery Global Open” The dermal filler is safe and effective for improving facial appearance.
August 2023 in “Diagnostics” Ultra-high-frequency ultrasound effectively evaluates the impact of hyaluronic acid fillers in reducing nasolabial fold wrinkles over time.
June 2019 in “Journal of Dermatological Treatment” BM-PHA is as effective and safe as Restylane Perlane for improving nasolabial folds with minor side effects.
108 citations
,
January 2003 in “Journal of Cosmetic Dermatology” Wrinkles form due to structural skin changes and vary in type and treatment response.
48 citations
,
October 2010 in “Archives of Dermatological Research” Juvéderm fillers effectively reduce wrinkles for up to 21 months with less filler needed for repeat treatments.
September 2019 in “Journal of Investigative Dermatology” Retinol significantly reduces neck wrinkles.
3 citations
,
September 2019 in “Skin appendage disorders” Women with Frontal Fibrosing Alopecia have more wrinkles near their ears than similar aged women without the condition.
April 2023 in “Journal of Investigative Dermatology” Urban pollution and sun exposure speed up skin aging and wrinkle formation in Chinese women, with pollution's effects becoming significant after age 45.
79 citations
,
January 1999 in “Dermatologic surgery” Different skin treatments work best for different levels of wrinkles and sun damage.
48 citations
,
May 2012 in “Journal of cosmetic and laser therapy” Fractional bipolar RF energy safely and effectively treats acne scars.
February 2017 in “Journal of Aesthetic Nursing” Skin needling is a safe, effective, and affordable treatment for various skin issues and enhances other aesthetic procedures.
February 2026 in “Journal of Cosmetic Dermatology” Polynucleotide injections improved eye wrinkles with few side effects.
October 2022 in “Zenodo (CERN European Organization for Nuclear Research)” Combining PDLLA and PRP effectively reduces wrinkles and improves skin quality.
41 citations
,
June 2010 in “Clinics in Dermatology” Smoking harms skin health, causing slower wound healing, more wrinkles, and worsening some skin conditions, but may protect against certain others.
2 citations
,
August 2023 in “Aesthetic Surgery Journal” RHA fillers are effective and safe for treating nasolabial folds in people of color.
28 citations
,
April 2024 in “Skin Research and Technology” Platelet-rich plasma (PRP) is effective and safe for improving skin appearance.
12 citations
,
October 2022 in “Facial Plastic Surgery” Polycaprolactone gel is effective and safe for treating nasolabial folds.
74 citations
,
June 2018 in “Cell death and disease” Restoring mitochondrial function in mice reversed their skin wrinkling and hair loss.
5 citations
,
July 2016 in “Journal of Clinical Hypertension” Men with severe early-onset baldness may have worse heart artery function and stiffer arteries if they have high blood pressure.
10 citations
,
April 2015 in “Netherlands Heart Journal” The conclusion is that there's no significant link between male pattern baldness and the severity of coronary artery disease.
120 citations
,
July 2005 in “Dermatologic surgery” Niacinamide improves aging skin and is safe for use in cosmetics.
Cosmetics can help with mild skin problems and daily care but must be used carefully to avoid skin irritation.
33 citations
,
May 2019 in “Aesthetic Plastic Surgery” Using hyaluronic acid fillers and laser together is generally safe and effective for facial rejuvenation, but careful planning is needed.
27 citations
,
May 2016 in “Dermatologic Surgery” Male faces age with more wrinkles and hair loss, influenced by both body changes and environmental factors.
24 citations
,
April 2017 in “Journal of Investigative Dermatology” Age, smoking, and lower BMI increase facial wrinkles; men wrinkle more than women, except in old age; pale skin and certain hormonal factors can protect against wrinkles.
3 citations
,
June 2017 in “Aesthetic plastic surgery” The new facial treatment improved wrinkles and skin thickness, with most patients seeing results within a month, despite some temporary swelling and bruising.
175 citations
,
November 2009 in “PLOS ONE” Women look young for their age due to larger lips, less sun damage, and genes that prevent gray hair and wrinkles.
114 citations
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February 2012 in “International Journal of Dermatology” Smoking harms the skin, causing early aging and increasing cancer risk, but stopping smoking can improve skin health.