25 citations
,
September 1998 in “The Journal of Steroid Biochemistry and Molecular Biology” Finasteride inhibits enzyme activity in rhesus macaques, suggesting they're useful for evaluating similar drugs.
April 2024 in “Journal of cosmetic dermatology” Minoxidil is less effective on eyebrows and eyelashes than scalp hair because these areas have lower enzyme activity needed to activate the drug.
June 2023 in “Nephrology Dialysis Transplantation” Enteric hyperoxaluria can cause severe kidney failure after bowel surgery.
January 2017 in “Elsevier eBooks” Antioxidants may help improve mitochondrial health and could be used to treat diseases related to cell damage.
December 2019 in “Arak Medical University Journal” Adding 7% chamomile extract to minoxidil reduces skin side effects in treating male hair loss.
3 citations
,
January 2009 in “Eclética Química” A simple and quick method was found to measure minoxidil in drugs accurately.
January 2026 in “Figshare” Finasteride can cause melasma, especially in people with darker skin.
April 2024 in “International Journal of Dermatology” Oral minoxidil may worsen hangover symptoms when combined with alcohol.
20 citations
,
October 2001 in “British Journal of Ophthalmology”
8 citations
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April 2004 in “The Journal of Urology” Doxazosin and finasteride negatively affect sexual function in men with BPH.
August 2024 in “Animal Bioscience” Exosomal miR-222-3p reduces melanin production in rabbits by targeting the SOX10 gene.
4 citations
,
October 2020 in “Toxicology Mechanisms and Methods” Hesperidin protects rat testicles from finasteride damage and improves sperm health.
September 2024 in “Vietnam Journal of Biotechnology” Astaxanthin may help protect hair cells from damage and prevent hair loss.
1 citations
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April 2004 in “Cancer” Imatinib mesylate can cause skin lightening, especially in Chinese patients, due to its effect on pigment production.
Oral Minoxidil can cause serious eye problems, but stopping it can improve vision.
June 2015 in “Reactions weekly” December 2012 in “Reactions weekly”
17 citations
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May 1998 in “Steroids” Researchers developed a model to predict how well certain compounds can block an enzyme related to hair loss and prostate issues, suggesting a 50 mg dose of finasteride might be effective based on lab and body data.
17 citations
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July 1995 in “International Journal of Dermatology” Minoxidil helps prevent hair loss from chemotherapy in rats.
August 2024 in “Journal of Drug Delivery Science and Technology” The new minoxidil formulation could better promote hair growth for treating androgenic alopecia.
March 2007 in “Journal of hypertension” Minoxidil effectively lowers blood pressure in patients with resistant hypertension.
March 2026 in “Frontiers in Physiology” Antioxidant treatments may help reduce Acute Mountain Sickness, but more research is needed.
1 citations
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March 2022 in “Journal of The American Academy of Dermatology” Adjusting minoxidil dosage may be safer than using bicalutamide for hair loss in women.
November 2025 in “Journal of Investigative Dermatology” Combining MMP-9 and JAK inhibitors can effectively prevent skin depigmentation in vitiligo.
23 citations
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March 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” ATP increases melanin production in skin after UV exposure, with the P2X7 receptor being crucial for this process.
11 citations
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February 2018 in “Archives of Pharmacal Research” Finasteride reduces melanin production, possibly treating hyperpigmentation and melanoma, but needs more safety research.
93 citations
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September 2014 in “Diabetes” Lack of 5α-Reductase type 1 can lead to insulin resistance and liver problems.
15 citations
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January 1995 in “Archives of Dermatological Research” Minoxidil boosts elastin production, potentially helping skin diseases.
March 2026 in “The Aging Male” PDE5 inhibitors cause earlier adverse events in BPH treatment, requiring careful monitoring.
19 citations
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June 2010 in “Journal of acupuncture and meridian studies” A plant extract was found to effectively block an enzyme related to male hormone-related diseases.