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Certain changes to the B-ring of androgen receptor ligands can increase their effectiveness for potential treatments of muscle and bone conditions.

Haircare products may expose users to harmful chemicals despite regulations.

New A-homo-B, 19-dinor steroids showed strong antiandrogenic activity without affecting the enzyme 5α-reductase or androgen receptor binding.

Finasteride affects brain stress and enzyme activity differently in various regions, possibly helping with liver-related brain issues.

The combination treatment showed a higher response rate but no significant survival benefits.

Drugs localize differently in hair strands based on their properties.

Certain ESR1 gene variations may affect hormone levels and fat distribution in women with high male hormone levels.

The conclusion suggests that treatments targeting root causes of chronic diseases may be developed by focusing on gene expression and lifestyle factors.

5α‐reductase isozymes are crucial for prostate development and health, and targeting them can help prevent and treat prostate issues.

The method accurately measures 19 steroid hormones in human blood and urine using a small sample and is suitable for large-scale monitoring.

American and Chinese ginseng have distinct metabolic profiles that help identify their origin.

New treatments for Hepatitis C show promise but need more research to confirm their safety and effectiveness for clinical use.

Gut microbes significantly affect brain steroid levels.

Adult mice with CBS deficiency show minimal health issues and normal lifespan despite high homocysteine levels.

Increasing isoleucine intake improved skin and health issues in an infant with maple syrup urine disease.

Smaller substituents at C-17 enhance the inhibitory activity of progesterone derivatives on 5alpha-reductase.

Endophytes from Southeast Asia and Japan can produce useful substances like enzymes and antibiotics.

Blocking BACE1 and BACE2 enzymes causes hair color loss in mice.

Dexamethasone reduces inflammation and delays skin cell changes caused by TPA.

Long-term use of hormonal contraceptives may harm liver function.

Scientists discovered a new way UVB light increases skin pigmentation through the ATP-P2X7 pathway.

Anabolic steroids can build muscle and strength but have risks and need more research on their clinical benefits and side effects.

Targeted protein degraders show promise in treating cancer but need to target more diverse proteins.

Higher ꝩ-GCS enzyme levels in PCOS patients may play a role in the disease.

The severity of symptoms in nonclassical congenital adrenal hyperplasia is not determined by CYP21A2 gene variations.

Using existing drugs for new purposes can effectively treat infections resistant to multiple antibiotics.

The report expanded knowledge of MBTPS1-related disorders by identifying new symptoms.

Non-classical 21-hydroxylase deficiency can be missed in newborn screenings and should be considered in cases of early puberty or virilization.