research Cutaneous Toxicities From Transplantation-Related Medications
Skin problems from transplant drugs are common and need careful management in organ transplant patients.
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360-390 / 1000+ results research New agents for cancer chemoprevention
Over 30 potential cancer prevention treatments are being tested, with some showing promise in early research.
research The pharmacology of methotrexate
Methotrexate treats various disorders by inhibiting DNA synthesis, but careful monitoring is needed to avoid toxicity and manage side effects.
research Hormesis and medicine
Low doses of some substances can be beneficial, while high doses can be harmful or toxic.
research Testosterone, cytochrome P450, and cardiac hypertrophy
Heart-specific steroid metabolism is crucial in cardiac hypertrophy.
research The severity of endogenous intoxication in the early stages after cesarean section in obesity
Obese women have higher toxin levels after cesarean sections, needing better treatment strategies.
research Lifestyle drugs: concept and impact on society
Lifestyle drugs are mainly used by wealthy people in India but could spread to others, affecting society and youth.
research In vitro biotransformation of finasteride in rat hepatic microsomes. Isolation and characterization of metabolites.
research Hepatotoxicity Secondary to A Drug to Lose Weight, "Orlistat": to take into Account as a Differential Diagnosis
The weight loss drug Orlistat can cause liver damage and should be used with caution, especially in those with liver or kidney issues.
research Disruptors of Androgen Action and Synthesis
Certain pesticides and fungicides can interfere with male hormone functions, potentially causing reproductive issues in male rats.
research Finasteride, A Steroid 5α-Reductase Inhibitor, Does Not Affect the Oxidative Metabolism of Antipyrine
Finasteride doesn't affect antipyrine metabolism, so interactions with cytochrome P-450 enzyme drugs are unlikely.
research Genetic Variation in CYP2B6, UGT1A4 and Sulfotransferases Is Associated with Disease-Free Survival in South African Breast Cancer Patients Treated with Tamoxifen
Genetic differences affect breast cancer treatment success with tamoxifen in South African patients.
research Systems for Mitochondria-Protective Cosmetic Actives: Opportunities in Post-Oncologic Skin Regeneration
Nanocarriers can improve skin treatments after cancer therapy by enhancing antioxidant delivery and effectiveness.
research ABSTRACTS—SYMPOSIA
Certain drugs can block changes in brain receptors caused by alcohol withdrawal.
research Low-Molecular-Weight Synthetic Antioxidants: Classification, Pharmacological Profile, Effectiveness and Trends
Synthetic antioxidants are effective, cheap, and stable, with some like zinc and cholecalciferol reducing child and cancer deaths, but the safety of additives like BHA, BHT, TBHQ, and PEG needs more research.
research The Antiandrogens
research DRUGS OF ABUSE | Hair
research Photostability and toxicity of finasteride, diclofenac and naproxen under simulating sunlight exposure: evaluation of the toxicity trend and of the packaging photoprotection
Sunlight exposure increases drug toxicity; amber glass best for protection.
research Abstract P5-09-21: Selective androgen receptor modulators (SARMs): Enobosarm as targeted therapy for the treatment of androgen receptor-positive breast cancer
Enobosarm may effectively treat androgen receptor-positive breast cancer with fewer side effects.
research Inhibition of the pro-oxidant effects of benoxaprofen on poiymorpbonuclear leucocytes by retinol acetate in vitro
Retinol acetate can reduce the harmful effects of the drug benoxaprofen on white blood cells.
research Estrogenic Potential of 2-Alkyl-4-(thio)chromenone 6-O-Sulfamates: Potent Inhibitors of Human Steroid Sulfatase
A substance called Compound 2g can strongly block STS (a hormone-related enzyme) without affecting estrogen levels, making it potentially good for treating breast cancer.
research Pharmacodynamic Evaluation: Endocrinology
The conclusion is that endocrinology significantly impacts medicine with various common medications used for treatment.
research Dermatological drugs and topical agents
Certain skin drugs and topical agents, including some natural extracts and fragrances, can cause allergic reactions. Some hair dyes and extensions, as well as minoxidil, a hair growth treatment, can also cause allergies. Botulinum toxin A can effectively reduce sweat but may have temporary side effects.
research Safety of Biological Therapies for Severe Asthma: An Analysis of Suspected Adverse Reactions Reported in the WHO Pharmacovigilance Database
Biologics for severe asthma have known side effects, but some new risks need more study.
research Management of the adverse effects of targeted therapy for cancer
Targeted cancer therapies can cause new side effects, requiring careful monitoring and management to ensure patient safety.
research Analysis of hormone antagonists in clinical and municipal wastewater by isotopic dilution liquid chromatography tandem mass spectrometry
Researchers developed a method to detect hormone-blocking drugs in wastewater and found them in Beijing's sewage, suggesting they can survive sewage treatment.
research Investigação das atividades alelopática, fitotóxica e antioxidante de extratos e frações de Tridax procumbens L. (Asteraceae). e Ouratea spectabilis (mart. ex engl.) engl. (Ochnaceae)
Tridax procumbens and Ouratea spectabilis can affect other plants' growth and have antioxidant benefits.
research Fadrozole and finasteride exposures modulate sex steroid- and thyroid hormone-related gene expression in Silurana (Xenopus) tropicalis early larval development
Fadrozole and finasteride change gene expression related to sex hormones and thyroid hormones in frog larvae development.
research ANTI-CANCER MEDICINS (CLASSIFICATION AND MECHANISMS OF ACTION)
Anti-cancer drugs are diverse and hard to classify due to their different forms and actions.
research Evaluation of an eucalyptus oil containing topical drug delivery system for selected steroid hormones
The eucalyptus oil system improved skin delivery of hormones, but safety concerns remain.