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Injecting lentiviral vectors into early gestation mice effectively targets skin stem cells for potential gene therapy.

The B2C promoter works in sheep cells but not in mouse embryos.

A new IL6ST gene variant may cause a unique form of hyper-IgE syndrome with skin abscesses and high IgE levels.

Old drugs are often used for new, different medical purposes in endocrine pharmacology.

ETS2 drives cancer progression in squamous cell carcinoma and is linked to poor patient outcomes.

The AVET system effectively delivers genes to human keratinocytes and may help treat skin diseases.

A new method using gold nanoshells and infrared light effectively delivers siRNA to cancer and stem cells with precision and minimal damage.

The engineered skin substitute helped grow skin with hair on mice.

SOX11 and SOX4 help skin cells act like embryonic cells to heal wounds in mice.

Platelet-derived exosomes offer better regenerative therapy but face challenges in isolation and regulation.

Fadrozole and finasteride change gene expression related to sex hormones and thyroid hormones in frog larvae development.

Gene therapy shows promise for treating skin disorders and cancer, but faces technical challenges.

Injecting recipient splenocytes into donors' thymus can prevent graft-versus-host disease.

LGR6+ stem cells may improve bone healing.

The document concludes that careful design of genetic fate mapping experiments is crucial for accurate cell lineage tracing in mice.

Male-to-female skin grafts in mice are rejected due to sex-linked antigens.

Increasing COX-2 in mouse skin causes bigger sebaceous glands and thinner hair, but stopping COX-2 can reverse hair thinning.

New cell sources for bone tissue engineering are promising due to easier harvesting and availability.

Pig skin cells can turn into mesodermal cells but lose their ability to become neural cells.

CRISPR-Cas9 can successfully edit genes in large mammals like Cashmere goats.

Maize hybrids show better early growth due to complex gene interactions from their parent strains.

A bull with a gene mutation was asymptomatic, synthetic retinoids cause hair loss, and new therapeutic targets were identified for skin diseases.

Engineered extracellular vesicles could improve CRISPR/Cas delivery, making gene editing safer and more effective.

A substance called Compound 2g can strongly block STS (a hormone-related enzyme) without affecting estrogen levels, making it potentially good for treating breast cancer.

Transfected cells with VEGF and FGF2 genes improve skin wound healing by enhancing blood flow and regeneration.

MSC-Exos can aid organ development and offer therapeutic benefits for various conditions.

Different types of resting melanocyte stem cells have unique characteristics and vary in their potential to become other cells.

A new method was developed to create better skin models for healing and reconstruction.

Key genes linked to important traits in Chinese sheep and goats have been identified, but challenges remain in breeding improvements.